Publications of Rolf M. Zinkernagel, 1996 Nobel Laureate in Physiology or Medicine, in The Journal of Immunology:
B Cell Activation State-Governed Formation of Germinal Centers following Viral Infection
Katja Fink, Nataly Manjarrez-Orduño, Anita Schildknecht, Jacqueline Weber, Beatrice M. Senn, Rolf M. Zinkernagel, and Hans Hengartner
J Immunol 2007 179:5877-5885; doi:10.4049/jimmunol.179.9.5877
Mechanisms of Neonatal Mucosal Antibody Protection
Nicola L. Harris, Iris Spoerri, Jacqueline F. Schopfer, Chiara Nembrini, Patrick Merky, Joanna Massacand, Joseph F. Urban, Jr., Alain Lamarre, Kurt Burki, Bernhard Odermatt, Rolf M. Zinkernagel, and Andrew J. Macpherson
J Immunol 2006 177:6256-6262; doi:10.4049/jimmunol.177.9.6256
CXCR5-Dependent Seeding of Follicular Niches by B and Th Cells Augments Antiviral B Cell Responses
Tobias Junt, Katja Fink, Reinhold Förster, Beatrice Senn, Martin Lipp, Masamichi Muramatsu, Rolf M. Zinkernagel, Burkhard Ludewig, and Hans Hengartner
J Immunol 2005 175:7109-7116; doi:10.4049/jimmunol.175.11.7109
Requirement for Neutralizing Antibodies to Control Bone Marrow Transplantation-Associated Persistent Viral Infection and to Reduce Immunopathology
Karl S. Lang, Mike Recher, Alexander A. Navarini, Stefan Freigang, Nicola L. Harris, Maries van den Broek, Bernhard Odermatt, Hans Hengartner, and Rolf M. Zinkernagel
J Immunol 2005 175:5524-5531; doi:10.4049/jimmunol.175.8.5524
Marginal Zone Macrophages and Immune Responses Against Viruses
Stephan Oehen, Bernhard Odermatt, Urs Karrer, Hans Hengartner, Rolf Zinkernagel, and Constantino López-Macías
J Immunol 2002 169:1453-1458; doi:10.4049/jimmunol.169.3.1453
Antiviral Immune Responses in the Absence of Organized Lymphoid T Cell Zones in plt/plt Mice
Tobias Junt, Hideki Nakano, Tilman Dumrese, Terutaka Kakiuchi, Bernhard Odermatt, Rolf M. Zinkernagel, Hans Hengartner, and Burkhard Ludewig
J Immunol 2002 168:6032-6040; doi:10.4049/jimmunol.168.12.6032
Rapid Peptide Turnover and Inefficient Presentation of Exogenous Antigen Critically Limit the Activation of Self-Reactive CTL by Dendritic Cells
Burkhard Ludewig, Kathy McCoy, Marcus Pericin, Adrian F. Ochsenbein, Tilman Dumrese, Bernhard Odermatt, Rene E. M. Toes, Cornelis J. M. Melief, Hans Hengartner, and Rolf M. Zinkernagel
J Immunol 2001 166:3678-3687; doi:10.4049/jimmunol.166.6.3678
Hypercholesterolemia Exacerbates Virus-Induced Immunopathologic Liver Disease Via Suppression of Antiviral Cytotoxic T Cell Responses
Burkhard Ludewig, Martin Jäggi, Tilman Dumrese, Karin Brduscha-Riem, Bernhard Odermatt, Hans Hengartner, and Rolf M. Zinkernagel
J Immunol 2001 166:3369-3376; doi:10.4049/jimmunol.166.5.3369
Correlation of T Cell Independence of Antibody Responses with Antigen Dose Reaching Secondary Lymphoid Organs: Implications for Splenectomized Patients and Vaccine Design
Adrian F. Ochsenbein, Daniel D. Pinschewer, Bernhard Odermatt, Adrian Ciurea, Hans Hengartner, and Rolf M. Zinkernagel
J Immunol 2000 164:6296-6302; doi:10.4049/jimmunol.164.12.6296
FTY720 Immunosuppression Impairs Effector T Cell Peripheral Homing Without Affecting Induction, Expansion, and Memory
Daniel D. Pinschewer, Adrian F. Ochsenbein, Bernhard Odermatt, Volker Brinkmann, Hans Hengartner, and Rolf M. Zinkernagel
J Immunol 2000 164:5761-5770; doi:10.4049/jimmunol.164.11.5761
Antiviral B Cell Memory in the Absence of Mature Follicular Dendritic Cell Networks and Classical Germinal Centers in TNFR1-/- Mice
U. Karrer, C. López-Macías, A. Oxenius, B. Odermatt, M. F. Bachmann, U. Kalinke, H. Bluethmann, H. Hengartner, and R. M. Zinkernagel
J Immunol 2000 164:768-778; doi:10.4049/jimmunol.164.2.768
IL-4 and IL-10 Antagonize IL-12-Mediated Protection Against Acute Vaccinia Virus Infection with a Limited Role of IFN-γ and Nitric Oxide Synthetase 2
Maries van den Broek, Martin F. Bachmann, Gabriele Köhler, Marijke Barner, Rüdiger Escher, Rolf Zinkernagel, and Manfred Kopf
J Immunol 2000 164:371-378; doi:10.4049/jimmunol.164.1.371
Protective Antiviral Cytotoxic T Cell Memory Is Most Efficiently Maintained by Restimulation Via Dendritic Cells
Burkhard Ludewig, Stephan Oehen, Federica Barchiesi, Reto A. Schwendener, Hans Hengartner, and Rolf M. Zinkernagel
J Immunol 1999 163:1839-1844
In Vivo Selection of Neutralization-Resistant Virus Variants But No Evidence of B Cell Tolerance in Lymphocytic Choriomeningitis Virus Carrier Mice Expressing a Transgenic Virus-Neutralizing Antibody
Peter Seiler, Beatrice M. Senn, Marie-Anne Bründler, Rolf M. Zinkernagel, Hans Hengartner, and Ulrich Kalinke
J Immunol 1999 162:4536-4541
Qualitative and Quantitative Requirements for CD4+ T Cell-Mediated Antiviral Protection
Kevin J. Maloy, Christoph Burkhart, Giulia Freer, Thomas Rülicke, Hanspeter Pircher, Dwight H. Kono, Argyrios N. Theofilopoulos, Burkhard Ludewig, Urs Hoffmann-Rohrer, Rolf M. Zinkernagel, and Hans Hengartner
J Immunol 1999 162:2867-2874
IL-12 Is Not Required for Induction of Type 1 Cytokine Responses in Viral Infections
Annette Oxenius, Urs Karrer, Rolf M. Zinkernagel, and Hans Hengartner
J Immunol 1999 162:965-973
Cutting Edge Commentary: Immune Responses in the Absence of Costimulation: Viruses Know the Trick
Martin F. Bachmann, Rolf M. Zinkernagel, and Annette Oxenius
J Immunol 1998 161:5791-5794
Lactate dehydrogenase-elevating virus (LDV): lifelong coexistence of virus and LDV-specific immunity
F van den Broek, R Spörri, C Even, P G Plagemann, E Hänseler, H Hengartner, and R M Zinkernagel
J Immunol 1997 159:1585-8
Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection
A Oxenius, M F Bachmann, D Mathis, C Benoist, R M Zinkernagel, and H Hengartner
J Immunol 1997 158:5717-26
Correlation of tolerogenicity of a viral antigen with its immunogenicity
M F Bachmann, T Fehr, G Freer, H Hengartner, and R M Zinkernagel
J Immunol 1997 158:5106-11
Different susceptibility of cytotoxic T cells to CD95 (Fas/Apo-1) ligand-mediated cell death after activation in vitro versus in vivo
S Ehl, U Hoffmann-Rohrer, S Nagata, H Hengartner, and R Zinkernagel
J Immunol 1996 156:2357-60
T cell development in CD8-/- mice. Thymic positive selection is biased toward the helper phenotype
M F Bachmann, A Oxenius, T W Mak, and R M Zinkernagel
J Immunol 1995 155:3727-33
Peptides control the gain and loss of allele specificity by mutated MHC class I molecules
H Hengel, K Burke, D Kyburz, R M Zinkernagel, and U H Koszinowski
J Immunol 1995 154:4557-64
Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells
M F Bachmann, T M Kündig, B Odermatt, H Hengartner, and R M Zinkernagel
J Immunol 1994 153:3386-97
MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice
D Moskophidis, F Lechner, H Hengartner, and R M Zinkernagel
J Immunol 1994 152:4976-83
How many specific B cells are needed to protect against a virus?
M F Bachmann, T M Kündig, C P Kalberer, H Hengartner, and R M Zinkernagel
J Immunol 1994 152:4235-41
Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells
M Battegay, D Moskophidis, H Waldner, M A Bründler, W P Fung-Leung, T W Mak, H Hengartner, and R M Zinkernagel
J Immunol 1993 151:5408-15
Peripheral T cells in mice lacking p56lck do not express significant antiviral effector functions
T J Molina, M F Bachmann, T M Kündig, R M Zinkernagel, and T W Mak
J Immunol 1993 151:699-706
Virus-specific cytotoxic T cell-mediated lysis of lymphocytes in vitro and in vivo
D Kyburz, D E Speiser, T Aebischer, H Hengartner, and R M Zinkernagel
J Immunol 1993 150:5051-8
Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha
P S Ohashi, S Oehen, P Aichele, H Pircher, B Odermatt, P Herrera, Y Higuchi, K Buerki, H Hengartner, and R M Zinkernagel
J Immunol 1993 150:5185-94
Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells
T M Kündig, M F Bachmann, L Lefrancois, L Puddington, H Hengartner, and R M Zinkernagel
J Immunol 1993 150:4450-6
T cell-dependent IFN-gamma exerts an antiviral effect in the central nervous system but not in peripheral solid organs
T M Kündig, H Hengartner, and R M Zinkernagel
J Immunol 1993 150:2316-21
Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection
D E Speiser, D Kyburz, U Stübi, H Hengartner, and R M Zinkernagel
J Immunol 1992 149:972-80
Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice
A Fontana, K Frei, S Bodmer, E Hofer, M H Schreier, M A Palladino, Jr, and R M Zinkernagel
J Immunol 1989 143:3230-4
Effects of treatment with IL-2 receptor specific monoclonal antibody in mice. Inhibition of cytotoxic T cell responses but not of T help
T P Leist, M Kohler, M Eppler, and R M Zinkernagel
J Immunol 1989 143:628-32
Treatment with high doses of anti-IgM prevents, but with lower doses accelerates autoimmune disease in (NZW x BXSB)F1 hybrid mice
A Cerny, M Starobinski, A W Hügin, S Sutter, R M Zinkernagel, and S Izui
J Immunol 1987 138:4222-8
Functional analysis of T lymphocyte subsets in antiviral host defense
T P Leist, S P Cobbold, H Waldmann, M Aguet, and R M Zinkernagel
J Immunol 1987 138:2278-81
Characterization of an Lyt-2+ alloreactive cytotoxic T cell clone specific for H-2Db that cross-reacts with I-Ek
M W Schilham, R Lang, R Benner, R M Zinkernagel, and H Hengartner
J Immunol 1986 137:2748-54
Effect of rabbit anti-asialo GM1 treatment in vivo or with anti-asialo GM1 plus complement in vitro on cytotoxic T cell activities
L Stitz, J Baenziger, H Pircher, H Hengartner, and R M Zinkernagel
J Immunol 1986 136:4674-80
Antibody mediated suppression of secondary IgM response in nude mice against vesicular stomatitis virus
S Charan and R M Zinkernagel
J Immunol 1986 136:3057-61
Natural killer cells vs cytotoxic T cells in the peripheral blood of virus-infected mice
L Stitz, A Althage, H Hengartner, and R Zinkernagel
J Immunol 1985 134:598-602
Specificity of in vitro cytotoxic T cell clones directed against vesicular stomatitis virus
K L Rosenthal, M B Oldstone, H Hengartner, and R M Zinkernagel
J Immunol 1983 131:475-8
Inability of mice to generate cytotoxic T lymphocytes to vesicular stomatitis virus restricted to H-2Kk or H-2Dk
K L Rosenthal and R M Zinkernagel
J Immunol 1981 126:446-51
Cross-reactive cytotoxic T cells to serologically distinct vesicular stomatitis virus
K L Rosenthal and R M Zinkernagel
J Immunol 1980 124:2301-8
On the immunocompetence of H-2 incompatible irradiation bone marrow chimeras
R M Zinkernagel, A Althage, G Callahan, and R M Welsh, Jr
J Immunol 1980 124:2356-65
Search for Suppression of T Cells Specific for the Second Nonhost H-2 Haplotype in F1 → P Irradiation Bone Marrow Chimeras
Rolf M. Zinkernagel and Alana Althage
J Immunol 1979 122:1742-1749
Cytotoxic Cells Induced During Lymphocytic Choriomeningitis Virus Infection of Mice: II. "Specificities" of the Natural Killer Cells
Raymond M. Welsh, Jr., Rolf M. Zinkernagel, and Linda A. Hallenbeck
J Immunol 1979 122:475-481
Target Antigens for H-2-Restricted Vesicular Stomatitis Virus-Specific Cytotoxic T Cells
R. M. Zinkernagel, A. Althage, and J. Holland
J Immunol 1978 121:744-748
Cell-Mediated Immune Response to Lymphocytic Choriomeningitis and Vaccinia Virus in Rats
Rolf M. Zinkernagel, Alana Althage, and Fred C. Jensen
J Immunol 1977 119:1242-1247
H-2 Compatibility Requirement for Virus-Specific T Cell-Mediated Effector Functions in Vivo: I. Specificity of T Cells Conferring Antiviral Protection Against Lymphocytic Choriomeningitis Virus Is Associated with H-2K and H
Rolf M. Zinkernagel and Raymond M. Welsh
J Immunol 1976 117:1495-1502
Inflammatory Process in Murine Lymphocytic Choriomeningitis Is Maximal in H-2K or H-2D Compatible Interactions
Peter C. Doherty, Malcolm B. C. Dunlop, Christopher R. Parish, and Rolf M. Zinkernagel
J Immunol 1976 117:187-190
Cytotoxic T Cell Activity is Strain-Specific in Outbred Mice Infected with Lymphocytic Choriomeningitis Virus
Rolf M. Zinkernagel, Malcolm B. C. Dunlop, and Peter C. Doherty
J Immunol 1975 115:1613-1616
Capacity of Sensitized Thymus-Derived Lymphocytes to Induce Fatal Lymphocytic Choriomeningitis Is Restricted by the H-2 Gene Complex
Peter C. Doherty and Rolf M. Zinkernagel
J Immunol 1975 114:30-33
Specificity and Development of Cytotoxic Thymus-Derived Lymphocytes in Lymphocytic Choriomeningitis
Peter C. Doherty, Rolf M. Zinkernagel, and Ian A. Ramshaw
J Immunol 1974 112:1548-1552
Early Appearance of Sensitized Lymphocytes in Mice Infected with Listeria Monocytogenes
Rolf M. Zinkernagel, Robert V. Blanden, and Rodney E. Langman
J Immunol 1974 112:496-501