Publications of Peter C. Doherty, 1996 Nobel Laureate in Physiology or Medicine, in The Journal of Immunology:
Fixed Expression of Single Influenza Virus-Specific TCR Chains Demonstrates the Capacity for TCR α- and β- Chain Diversity in the Face of Peptide-MHC Class I Specificity
E. Bridie Clemens, Peter C. Doherty, Nicole L. La Gruta, and Stephen J. Turner
J Immunol 2015 194:898-910; doi:10.4049/jimmunol.1401792
Helping Themselves: Optimal Virus-Specific CD4 T Cell Responses Require Help via CD4 T Cell Licensing of Dendritic Cells
Matthew R. Olson, Shirley G. K. Seah, Jolie Cullen, Marie Greyer, Kathryn Edenborough, Peter C. Doherty, Sammy Bedoui, Andrew M. Lew, and Stephen J. Turner
J Immunol 2014 193:5420-5433; doi:10.4049/jimmunol.1303359
The Influenza Virus–Specific CTL Immunodominance Hierarchy in Mice Is Determined by the Relative Frequency of High-Avidity T Cells
Tania Cukalac, Jesseka Chadderton, Weiguang Zeng, Jolie G. Cullen, Wan Ting Kan, Peter C. Doherty, David C. Jackson, Stephen J. Turner, and Nicole L. La Gruta
J Immunol 2014 192:4061-4068; doi:10.4049/jimmunol.1301403
Affinity Thresholds for Naive CD8+ CTL Activation by Peptides and Engineered Influenza A Viruses
Alice E. Denton, Robb Wesselingh, Stephanie Gras, Carole Guillonneau, Matthew R. Olson, Justine D. Mintern, Weiguang Zeng, David C. Jackson, Jamie Rossjohn, Philip D. Hodgkin, Peter C. Doherty, and Stephen J. Turner
J Immunol 2011 187:5733-5744; doi:10.4049/jimmunol.1003937
The Tetramer Transformation
Peter C. Doherty
J Immunol 2011 187:5-6; doi:10.4049/jimmunol.1101297
Effect of MHC Class I Diversification on Influenza Epitope-Specific CD8+ T Cell Precursor Frequency and Subsequent Effector Function
E. Bridie Day, Kim L. Charlton, Nicole L. La Gruta, Peter C. Doherty, and Stephen J. Turner
J Immunol 2011 186:6319-6328; doi:10.4049/jimmunol.1000883
Influenza Epitope-Specific CD8+ T Cell Avidity, but Not Cytokine Polyfunctionality, Can Be Determined by TCRβ Clonotype
Jessica M. Moffat, Andreas Handel, Peter C. Doherty, Stephen J. Turner, Paul G. Thomas, and Nicole L. La Gruta
J Immunol 2010 185:6850-6856; doi:10.4049/jimmunol.1002025
Physiological Numbers of CD4+ T Cells Generate Weak Recall Responses Following Influenza Virus Challenge
Paul G. Thomas, Scott A. Brown, Melissa Y. Morris, Wen Yue, Jenny So, Cory Reynolds, Richard J. Webby, and Peter C. Doherty
J Immunol 2010 184:1721-1727; doi:10.4049/jimmunol.0901427
Interplay between Chromatin Remodeling and Epigenetic Changes during Lineage-Specific Commitment to Granzyme B Expression
Torsten Juelich, Elissa Sutcliffe, Alice Denton, Yiqing He, Peter C. Doherty, Christopher Parish, Steven J. Turner, David Tremethick, and Sudha Rao
J Immunol 2009 183:7063-7072; doi:10.4049/jimmunol.0901522
Cell Cycle-Related Acquisition of Cytotoxic Mediators Defines the Progressive Differentiation to Effector Status for Virus-Specific CD8+ T Cells
Misty R. Jenkins, Justine Mintern, Nicole L. La Gruta, Katherine Kedzierska, Peter C. Doherty, and Stephen J. Turner
J Immunol 2008 181:3818-3822; doi:10.4049/jimmunol.181.6.3818
Terminal Deoxynucleotidyltransferase Is Required for the Establishment of Private Virus-Specific CD8+ TCR Repertoires and Facilitates Optimal CTL Responses
Katherine Kedzierska, Paul G. Thomas, Vanessa Venturi, Miles P. Davenport, Peter C. Doherty, Stephen J. Turner, and Nicole L. La Gruta
J Immunol 2008 181:2556-2562; doi:10.4049/jimmunol.181.4.2556
Homogenization of TCR Repertoires within Secondary CD62Lhigh and CD62Llow Virus-Specific CD8+ T Cell Populations
Katherine Kedzierska, Vanessa Venturi, Sophie A. Valkenburg, Miles P. Davenport, Stephen J. Turner, and Peter C. Doherty
J Immunol 2008 180:7938-7947; doi:10.4049/jimmunol.180.12.7938
Cutting Edge: Tissue-Resident Memory CTL Down-Regulate Cytolytic Molecule Expression following Virus Clearance
Justine D. Mintern, Carole Guillonneau, Francis R. Carbone, Peter C. Doherty, and Stephen J. Turner
J Immunol 2007 179:7220-7224; doi:10.4049/jimmunol.179.11.7220
The Context of Epitope Presentation Can Influence Functional Quality of Recalled Influenza A Virus-Specific Memory CD8+ T Cells
E. Bridie Day, Weiguang Zeng, Peter C. Doherty, David C. Jackson, Katherine Kedzierska, and Stephen J. Turner
J Immunol 2007 179:2187-2194; doi:10.4049/jimmunol.179.4.2187
Heterogeneity of Effector Phenotype for Acute Phase and Memory Influenza A Virus-Specific CTL
Misty R. Jenkins, Katherine Kedzierska, Peter C. Doherty, and Stephen J. Turner
J Immunol 2007 179:64-70; doi:10.4049/jimmunol.179.1.64
Disregulated Influenza A Virus-Specific CD8+ T Cell Homeostasis in the Absence of IFN-γ Signaling
Stephen J. Turner, Elvia Olivas, Astrid Gutierrez, Gabriela Diaz, and Peter C. Doherty
J Immunol 2007 178:7616-7622; doi:10.4049/jimmunol.178.12.7616
Virus-Specific CD8+ T Cells in the Liver: Armed and Ready to Kill
Rachael Keating, Wen Yue, John A. Rutigliano, Jenny So, Elvia Olivas, Paul G. Thomas, and Peter C. Doherty
J Immunol 2007 178:2737-2745; doi:10.4049/jimmunol.178.5.2737
Hidden Epitopes Emerge in Secondary Influenza Virus-Specific CD8+ T Cell Reponses
Paul G. Thomas, Scott A. Brown, Rachael Keating, Wen Yue, Melissa Y. Morris, Jenny So, Richard J. Webby, and Peter C. Doherty
J Immunol 2007 178:3091-3098; doi:10.4049/jimmunol.178.5.3091
Mucosal HIV-1 Pox Virus Prime-Boost Immunization Induces High-Avidity CD8+ T Cells with Regime-Dependent Cytokine/Granzyme B Profiles
Charani Ranasinghe, Stephen J. Turner, Craig McArthur, Duncan B. Sutherland, Jee-Hye Kim, Peter C. Doherty, and Ian A. Ramshaw
J Immunol 2007 178:2370-2379; doi:10.4049/jimmunol.178.4.2370
An In Vivo Cytotoxicity Threshold for Influenza A Virus-Specific Effector and Memory CD8+ T Cells
John Stambas, Peter C. Doherty, and Stephen J. Turner
J Immunol 2007 178:1285-1292; doi:10.4049/jimmunol.178.3.1285
Immunoproteasome Subunit Deficiencies Impact Differentially on Two Immunodominant Influenza Virus-Specific CD8+ T Cell Responses
Ken C. Pang, Megan T. Sanders, John J. Monaco, Peter C. Doherty, Stephen J. Turner, and Weisan Chen
J Immunol 2006 177:7680-7688; doi:10.4049/jimmunol.177.11.7680
Quantification of Repertoire Diversity of Influenza-Specific Epitopes with Predominant Public or Private TCR Usage
Katherine Kedzierska, E. Bridie Day, Jing Pi, Stephen B. Heard, Peter C. Doherty, Stephen J. Turner, and Stanley Perlman
J Immunol 2006 177:6705-6712; doi:10.4049/jimmunol.177.10.6705
Addition of a Prominent Epitope Affects Influenza A Virus-Specific CD8+ T Cell Immunodominance Hierarchies When Antigen Is Limiting
Misty Rayna Jenkins, Richard Webby, Peter C. Doherty, and Stephen J. Turner
J Immunol 2006 177:2917-2925; doi:10.4049/jimmunol.177.5.2917
Hierarchies in Cytokine Expression Profiles for Acute and Resolving Influenza Virus-Specific CD8+ T Cell Responses: Correlation of Cytokine Profile and TCR Avidity
Nicole L. La Gruta, Stephen J. Turner, and Peter C. Doherty
J Immunol 2004 172:5553-5560; doi:10.4049/jimmunol.172.9.5553
Clustering of Th Cell Epitopes on Exposed Regions of HIV Envelope Despite Defects in Antibody Activity
Scott A. Brown, John Stambas, Xiaoyan Zhan, Karen S. Slobod, Chris Coleclough, Amy Zirkel, Sherri Surman, Stephen W. White, Peter C. Doherty, and Julia L. Hurwitz
J Immunol 2003 171:4140-4148; doi:10.4049/jimmunol.171.8.4140
Reduced Functional Capacity of CD8+ T Cells Expanded by Post-Exposure Vaccination of γ-Herpesvirus-Infected CD4-Deficient Mice
Haiyan Liu, Samita Andreansky, Gabriela Diaz, Twala Hogg, and Peter C. Doherty
J Immunol 2002 168:3477-3483; doi:10.4049/jimmunol.168.7.3477
The Role of Antigen in the Localization of Naive, Acutely Activated, and Memory CD8+ T Cells to the Lung During Influenza Pneumonia
David J. Topham, Maria R. Castrucci, F. Suzette Wingo, Gabrielle T. Belz, and Peter C. Doherty
J Immunol 2001 167:6983-6990; doi:10.4049/jimmunol.167.12.6983
Concurrent Naive and Memory CD8+ T Cell Responses to an Influenza
Stephen J. Turner, Richard Cross, Weidong Xie, and Peter C. Doherty
J Immunol 2001 167:2753-2758; doi:10.4049/jimmunol.167.5.2753
Cutting Edge: Culture with High Doses of Viral Peptide Induces Previously Unprimed CD8+ T Cells to Produce Cytokine
Janice M. Riberdy, Amy Zirkel, Sherri Surman, Julia L. Hurwitz, and Peter C. Doherty
J Immunol 2001 167:2437-2440; doi:10.4049/jimmunol.167.5.2437
Diversity of Epitope and Cytokine Profiles for Primary and Secondary Influenza A Virus-Specific CD8+ T Cell Responses
Gabrielle T. Belz, Weidong Xie, and Peter C. Doherty
J Immunol 2001 166:4627-4633; doi:10.4049/jimmunol.166.7.4627
Diversity of Epitope and Cytokine Profiles for Primary and Secondary Influenza A Virus-Specific CD8+ T Cell Responses
Gabrielle T. Belz, Weidong Xie, and Peter C. Doherty
J Immunol 2001 166:4627-4633; doi:10.4049/jimmunol.166.7.4627
Contemporary Analysis of MHC-Related Immunodominance Hierarchies in the CD8+ T Cell Response to Influenza A Viruses
Gabrielle T. Belz, Philip G. Stevenson, and Peter C. Doherty
J Immunol 2000 165:2404-2409; doi:10.4049/jimmunol.165.5.2404
Analysis of the Virus-Specific and Nonspecific B Cell Response to a Persistent B-Lymphotropic Gammaherpesvirus
Mark Y. Sangster, David J. Topham, Sybil D'Costa, Rhonda D. Cardin, Tony N. Marion, Linda K. Myers, and Peter C. Doherty
J Immunol 2000 164:1820-1828; doi:10.4049/jimmunol.164.4.1820
Longitudinal Analysis of the Acute Sendai Virus-Specific CD4+ T Cell Response and Memory
David J. Topham and Peter C. Doherty
J Immunol 1998 161:4530-4535
Antiviral Cytotoxic Activity Across a Species Barrier in Mixed Xenogeneic Chimeras: Functional Restriction to Host MHC
Yolonda L. Colson, Ralph A. Tripp, Peter C. Doherty, Sherry M. Wren, Michael Neipp, Ashraf Y. Abou El-Ezz, and Suzanne T. Ildstad
J Immunol 1998 160:3790-3796
CD8+ T cells clear influenza virus by perforin or Fas-dependent processes
D J Topham, R A Tripp, and P C Doherty
J Immunol 1997 159:5197-200
Bone marrow can function as a lymphoid organ during a primary immune response under conditions of disrupted lymphocyte trafficking
R A Tripp, D J Topham, S R Watson, and P C Doherty
J Immunol 1997 158:3716-20
Lethal synergism between influenza infection and staphylococcal enterotoxin B in mice
W J Zhang, S Sarawar, P Nguyen, K Daly, J E Rehg, P C Doherty, D L Woodland, and M A Blackman
J Immunol 1996 157:5049-60
Quantitative analysis of the influenza virus-specific CD4+ T cell memory in the absence of B cells and Ig
D J Topham, R A Tripp, A M Hamilton-Easton, S R Sarawar, and P C Doherty
J Immunol 1996 157:2947-52
Recombinant polyepitope vaccines for the delivery of multiple CD8 cytotoxic T cell epitopes
S A Thomson, S L Elliott, M A Sherritt, K W Sproat, B E Coupar, A A Scalzo, C A Forbes, A M Ladhams, X Y Mo, R A Tripp, P C Doherty, D J Moss, and A Suhrbier
J Immunol 1996 157:822-6
Laser light suicide of proliferating virus-specific CD8+ T cells in an in vivo response
R A Tripp, J M Lahti, and P C Doherty
J Immunol 1995 155:3719-21
Characteristics of the influenza virus-specific CD8+ T cell response in mice homozygous for disruption of the H-2lAb gene
R A Tripp, S R Sarawar, and P C Doherty
J Immunol 1995 155:2955-9
Anatomical environment as a determinant in viral immunity
P C Doherty
J Immunol 1995 155:1023-7
Subverting lymph node trafficking by treatment with the Mel-14 monoclonal antibody to L-selectin does not prevent an effective host response to Sendai virus
S Hou, L Hyland, L M Bradley, S R Watson, and P C Doherty
J Immunol 1995 155:252-8
Recruitment and proliferation of CD8+ T cells in respiratory virus infections
R A Tripp, S Hou, A McMickle, J Houston, and P C Doherty
J Immunol 1995 154:6013-21
Temporal loss of the activated L-selectin-low phenotype for virus-specific CD8+ memory T cells
R A Tripp, S Hou, and P C Doherty
J Immunol 1995 154:5870-5
Functional analysis of the TCR alpha- beta+ cells that accumulate in the pneumonic lung of influenza virus-infected TCR-alpha-/- mice
M Eichelberger, A McMickle, M Blackman, P Mombaerts, S Tonegawa, and P C Doherty
J Immunol 1995 154:1569-76
Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype
S R Sarawar, M Sangster, R L Coffman, and P C Doherty
J Immunol 1994 153:1246-53
Prominent usage of V beta 8.3 T cells in the H-2Db-restricted response to an influenza A virus nucleoprotein epitope
A M Deckhut, W Allan, A McMickle, M Eichelberger, M A Blackman, P C Doherty, and D L Woodland
J Immunol 1993 151:2658-66
Partitioning of responder CD8+ T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype
S Hou and P C Doherty
J Immunol 1993 150:5494-500
Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells
S Hou, P C Doherty, M Zijlstra, R Jaenisch, and J M Katz
J Immunol 1992 149:1319-25
Evidence for clonal expansion of T cell receptor V gamma II+ T cells in the synovial fluid of patients with arthritis
P J Doherty, S X Yang, R M Laxer, E D Silverman, R Inman, and S Pan
J Immunol 1992 149:295-9
Activation status of the CD4-8- gamma delta-T cells recovered from mice with influenza pneumonia
M Eichelberger, W Allan, S R Carding, K Bottomly, and P C Doherty
J Immunol 1991 147:2069-74
Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells
W Allan, Z Tabi, A Cleary, and P C Doherty
J Immunol 1990 144:3980-6
Tumor necrosis factor inhibits the development of viral meningitis or induces rapid death depending on the severity of inflammation at time of administration
P C Doherty, J E Allan, and I A Clark
J Immunol 1989 142:3576-80
Phenotypic and functional analysis of the cellular response in regional lymphoid tissue during an acute virus infection
F Lynch, P C Doherty, and R Ceredig
J Immunol 1989 142:3592-8
Antagonistic effects of calcium ionophores and phorbol esters on T cell receptor mRNA levels in human thymocytes
H Martinez-Valdez, P J Doherty, E Thompson, S H Benedict, E W Gelfand, and A Cohen
J Immunol 1988 140:361-6
Anti-Thy-1 plus complement-treated, cultured bone marrow cells resemble fetal thymocytes in killer cell function and marker expression
J L Hurwitz, E C McAndrew, and P C Doherty
J Immunol 1986 137:1757-63
Cross-reactivity patterns of influenza-specific cytotoxic T lymphocytes from H-2Kb mutant mice
J L Hurwitz, P J Wettstein, J R Bennink, and P C Doherty
J Immunol 1983 131:471-4
Limit-dilution analysis of weak influenza-immune T cell responses associated with H-2Kb and H-2Db
M Allouche, J A Owen, and P C Doherty
J Immunol 1982 129:689-93
Virus-immune and alloreactive response characteristics of thymocytes and spleen cells from young mice
D H Schwartz and P C Doherty
J Immunol 1981 127:1411-4
Early dominance of irradiated host cells in the responder profiles of thymocytes from P leads to F1 radiation chimeras
R Korngold, J R Bennink, and P C Doherty
J Immunol 1981 127:124-9
Negatively selected H-2bml and H-2b cells stimulated with vaccinia virus completely discriminate between mutant and wild-type H-2K alleles
P C Doherty, J R Bennink, and P J Wettstein
J Immunol 1981 126:131-3
A Monoclonal Antibody to Viral Glycoprotein Blocks Virus-Immune Effector T Cells Operating at H-2Dd but Not at H-2Kd
Mark E. Frankel, Rita B. Effros, Peter C. Doherty, and Walter U. Gerhard
J Immunol 1979 123:2438-2440
Inhibition of Influenza-Immune T Cell Effector Function by Virus-Specific Hybridoma Antibody
Rita B. Effros, Mark E. Frankel, Walter Gerhard, and Peter C. Doherty
J Immunol 1979 123:1343-1346
Inflammatory Process in Murine Lymphocytic Choriomeningitis Is Maximal in H-2K or H-2D Compatible Interactions
Peter C. Doherty, Malcolm B. C. Dunlop, Christopher R. Parish, and Rolf M. Zinkernagel
J Immunol 1976 117:187-190
Cytotoxic T Cell Activity is Strain-Specific in Outbred Mice Infected with Lymphocytic Choriomeningitis Virus
Rolf M. Zinkernagel, Malcolm B. C. Dunlop, and Peter C. Doherty
J Immunol 1975 115:1613-1616
Capacity of Sensitized Thymus-Derived Lymphocytes to Induce Fatal Lymphocytic Choriomeningitis Is Restricted by the H-2 Gene Complex
Peter C. Doherty and Rolf M. Zinkernagel
J Immunol 1975 114:30-33
Specificity and Development of Cytotoxic Thymus-Derived Lymphocytes in Lymphocytic Choriomeningitis
Peter C. Doherty, Rolf M. Zinkernagel, and Ian A. Ramshaw
J Immunol 1974 112:1548-1552