If you would like to include your position on this list, please contact us using these guidelines.
Department of Health
and Human Services
National Institutes of Health
National Institute of Allergy and Infectious Diseases
Postdoctoral Fellow—Pathogenesis of HIV Infection
The National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research (DIR), Laboratory of Immunoregulation (LIR), HIV-Specific Immunity Section (HSIS) is seeking an outstanding postdoctoral fellow to participate in basic and clinical research in the pathogenesis of HIV infection.
DIR’s mission is to design, initiate, and conduct important basic science and clinical investigations in cutting-edge areas of infectious diseases and allergy/immunology, particularly those of major public health importance. The scientific research program of HSIS is focused on investigating humoral immunity in HIV infection.
There is a growing consensus that effective vaccines for HIV will require a humoral response capable of recognizing diverse isolates. The laboratory has recruited a cohort of patients with a broad and potent neutralizing antibody response to HIV. Sera and cells from these patients are being used in state-of-the-art assays for neutralization, sorting, and single-cell expansion of antigen-specific B cells and for cloning and expression of immunoglobulin genes to better understand the basis of the neutralizing antibody response to HIV.
Applicants should have a Ph.D. and/or M.D. Experience in measuring humoral immune responses in humans or animals and basic molecular biology techniques is desirable. Salary range is commensurate with experience.
Interested candidates may contact Mark Connors, M.D., at mconnors@niaid.nih.gov for additional information about the position. To apply, candidates must submit a curriculum vitae, a bibliography, three letters of reference, a detailed statement of clinical research interests, and reprints of up to three selected publications to National Institute of Allergy and Infectious Diseases, Division of Intramural Research, c/o LIR Office of the Chief, Attn: Dr. Marybeth Daucher (mdaucher@niaid.nih.gov), 10 Center Drive, Room 6A19, Bethesda, MD 20892-1884 by April 30, 2010.
For further information about NIAID and available job opportunities, visit www.niaid.nih.gov/careers/phi4.
HHS, NIH, and NIAID are proud to be Equal Opportunity Employers.
Posted: March 12, 2010
The Feeney Laboratory in the Division of Experimental Medicine at UCSF is seeking highly motivated postdoctoral research fellows to design and conduct research related to vertical HIV transmission, the infant immune response to HIV and malaria, and development of novel technologies for assessing pathogen-specific immune responses using small infant blood samples. The successful candidate will pursue patient-oriented immunology research based on international collaborations in Africa and the Caribbean. The mission of the Division of Experimental Medicine is to understand the human immune system so that lifesaving therapies and vaccines can be developed to protect against chronic infectious diseases of global importance, and to establish a training environment that fosters patient-oriented research in the U.S. and abroad.
Candidates should possess a Ph.D. and/or M.D. and have a strong background in immunology or infectious disease research. Experience with multiparametric flow cytometry and/or molecular biology techniques including RT-PCR is a plus. Excellent communication and writing skills are essential.
Interested candidates should email a cover letter, CV, and 3 references to Dr. Margaret Feeney, Associate Professor, Division of Experimental Medicine, UCSF (feeneylabucsf@gmail.com). Phone 415-206-8218.
Posted: March 10, 2010
Investigator: Lisa A. Spencer, PhD
Division of Allergy and Inflammation
Harvard Medical School/Beth Israel Deaconess Medical Center
We are currently seeking exceptionally motivated postdoctoral fellows to carry out ongoing studies investigating the immunobiology of innate immune leukocytes, specifically pertaining to allergic diseases of the lung and gastrointestinal tract. Projects involve basic and applied studies with primary human cells and mouse models, and seek to understand: 1) mechanisms by which human eosinophil functions are regulated; 2) immunomodulatory capacities of innate immune leukocytes in allergic respiratory and gastrointestinal diseases; and 3) mechanisms by which eosinophils participate in fibrotic processes associated with pulmonary and cardiovascular diseases.
Successful applicants should hold a Ph.D. (or equivalent) in immunology, cell biology or a related biomedical field. Evidence of a strong publication record and previous experience in tissue culture, flow cytometry, histopathology, or microscopy is preferred.
Qualified applicants should send a cover letter including a statement of research interests, curriculum vitae and contact information for three references to Dr. Lisa Spencer at the address below. Electronic submissions are encouraged.
Dr. Lisa A. Spencer
Beth Israel Deaconess Medical Center
330 Brookline Avenue, E/CLS Rm 935
Boston, MA 02215
Phone: (617) 735-4104
Fax: (617) 735-4115
Email: lspencer@bidmc.harvard.edu
Posted: March 9, 2010
Postdoctoral Research Associate in a laboratory studying the antiapoptotic BCL2 family member, MCL1. The focus of the project is on the critical role of MCL1 in regulating the development and function of cells of the immune system, as can be studied in MCL1 transgenic mice. The long-term goal is to understand how dysregulated expression of MCL1 contributes to immune dysfunction and cancer.
The following website gives additional information about the laboratory:
http://dms.dartmouth.edu/faculty/facultydb/view.php?uid=144
Independence and a high degree of self-motivation are encouraged in the
laboratory, as is the ability to work with others. Candidates must have a
Ph.D. or comparable degree in Molecular Biology, Immunology, Biochemistry,
Pharmacology, or a related field. A background in immunology/B cell
development and/or reproductive hormones would also be useful, as would
knowledge of molecular and cellular biologic techniques, flow cytometry,
and work with animals. This position is funded by the NIH and is available
immediately.
Please send CV and the names of several references to
Ruth.W.Craig@Dartmouth.edu
or
Dr. Ruth W. Craig
Department of Pharmacology and Toxicology Dartmouth Medical School
Hanover, NH 03755
Telephone: 603 650-1657
Fax: 603 650-1129
Posted: March 8, 2010
A postdoctoral position funded by a 5-year grant is available in the Department of Microbiology and Immunology at the University of Maryland School of Medicine, Baltimore, USA, to model inherited lipid storage diseases using patient-derived induced pluripotent stem (iPS) cells and reprogramming technology.
POST-DOCTORAL TRAINING AREA
The post-doctoral candidate will use reprogramming technology to generate iPS cells from fibroblasts and other cell types of patients harboring homo- and hetero-allelic mutations in the glucocerebrosidase gene. The post-doctoral candidate will carry out directed differentiation of iPS cells into hematopoietic and neuronal cell lineages, to study the effect of different mutations on the function of the affected cell types. The project involves studying the molecular mechanisms by which specific mutations in the affected gene cause intracellular transport abnormalities, lysosomal malfunction, abnormal production and release of tissue hydrolases, and how this leads to hematologic and neurological abnormalities. The post-doctoral fellow will also participate in developing new technology for successful engraftment of iPS-derived hematopoietic stem cells. This is an excellent opportunity for interdisciplinary post-doctoral training in Stem Cell Biology and Molecular Medicine. Our Laboratory is part of the newly created Center for Stem Cell Biology & Regenerative Medicine, and the Department of Microbiology and Immunology has more than 70 interacting Principal Investigators with diverse interests in Virology, Immunology, Bacterial Pathogenesis, Cell and Molecular Biology. The city of Baltimore is close to Washington and part of an exciting cultural hub.
REQUIREMENTS
The post-doctoral candidate is required to have a PhD degree in Molecular, Cellular Biology or a related field, a documented record of scientific accomplishment, have good oral and written communication skills, and be able to work independently. Salary is commensurate with experience and accomplishments. Interested individuals should send or E-Mail a letter stating research interests and experience, a CV and contact information for three references to:
Ricardo A. Feldman, PhD.
Associate Professor
Department of Microbiology and Immunology
University of Maryland School of Medicine
Howard Hall, Room 319C.
660 West Redwood Street
Baltimore, MD 21201
Tel.: (410) 706-4198
FAX.: (410) 706-2129
E-mail address: rfeldman@umaryland.edu
http://medschool.som.umaryland.edu/FACULTYRESEARCHPROFILE/viewprofile.aspx?id=276
Posted: March 8, 2010
Several postdoctoral positions are available (July 2010) in an exciting new Department to study the inflammation, cancer and stem cell-based cancer vaccines.
Our lab is currently focusing on understanding gp96, an endoplasmic reticulum master chaperone of Toll-like receptors, in regulating immune response against infection, tumor and self-antigens (Pubmed/Google Scholar term: Zihai Li). Ongoing work are in the area of defining the molecular mechanism of gp96 in chaperoning TLRs, understanding the roles of gp96 in regulating hematopoiesis and thrombopoiesis, and teasing out the roles of macrophage versus dendritic cells in the development of and immunosurveillance against cancer. The lab has also become interested in the biology of both pluripotent stem cells and hematopoietic stem cells and found that stem cells can be used as a cancer vaccine. Available projects include: (a) Mechanistic study of the interplay amongst gp96, ER stress and cancer using conditional gp96 null mice. (b) Mechanistic and translational study of human embryonic stem cells as cancer vaccines. (c) Development of novel gp96 inhibitors against cancer and inflammation via high throughput screening and computational/structural modeling.
Located on the Atlantic coast in South Carolina, Charleston boasts one of the nation’s most historic downtown areas and offers a superb quality of life. Applicants with recent Ph.D. or M.D./Ph.D., original mind and driving work ethics, publications in international journals and a strong background in relevant topics are encouraged to apply. Please send via email curriculum vitae, a description of research accomplishments and names of three references to: Zihai Li, M.D., Ph.D., Chairman, Department of Immunobiology & Cancer Immunology; e-mail: zihai@musc.edu.
Posted: March 8, 2010
Investigator: Clara Abraham, M.D.
Intestinal inflammation
Yale University, New Haven, CT
POSTDOCTORAL POSITIONS are available for research on intestinal inflammatory responses. Projects include:
1) Understanding immunological pathways implicated in human inflammatory bowel disease through studies in both primary human immune cells and murine model systems.
2) T cell homeostasis and trafficking in murine models of intestinal inflammation.
Postdoctoral positions: Candidates must have a Ph.D. or equivalent degree with a strong background in immunology and/or molecular biology and biochemistry. Experience in cellular and molecular immunology, biochemistry, molecular biology, multiparameter flow cytometry, gene expression analysis, and murine models of disease and transgenic/knock-out mouse-related work is desired.
Please send curriculum vitae, three names of reference and a one page summary of research background and interests to Clara Abraham, M.D. (Clara.Abraham@yale.edu).
Yale University is an Affirmative Action/Equal Opportunity Employer.
Posted: March 5, 2010
A postdoctoral research position for a highly motivated researcher is available in the Grotenbreg laboratory ( http://immunology.nus.edu.sg/grotenbreg_lab/home.html). Ongoing studies involve the development of novel tools and strategies for the investigation of cellular immune responses against clinically relevant pathogens in Asian populations, as well as studies that focus on the structural basis of how MHC-TCR affinity affects the development and functional properties of T cells.
Requirements:
1. A doctoral degree from a well-recognized institution and a strong background in immunology, structural biology or a related life science discipline.
2. Demonstrated creativity and technical independence with molecular, biochemical and/or immunological techniques.
3. The ability to take initiative and work independently, as well as a willingness to share knowledge and expertise within an international and interdisciplinary team.
4. A good publication record in recognized peer-reviewed journals will be highly advantageous.
Motivated individuals should send their application, up-to-date curriculum vitae and two letters of reference to the address below. An outstanding application would include a short description of what attracts you in our research. Salary and benefits will be commensurable to educational qualifications and working experience. To ensure full consideration, all application materials should be presented in a single submission. Applications will be reviewed starting March 01, 2010 and are accepted until the position is filled.
Dr. Gijsbert Grotenbreg
National University of Singapore
Departments of Microbiology and Biological Sciences
Immunology Programme
28 Medical Drive
Centre for Life Sciences, #03-05
Singapore 117456
Email: gijsbert.grotenbreg@gmail.com
Posted: March 5, 2010
SIV immunopathogenesis
A postdoctoral position is available immediately to study the pathogenesis of SIV infection in Rhesus macaques, with particular emphasis on the biology of SIV mucosal transmission and immunological impact of virus adaptation to new hosts. The candidate should have a PhD/MD degree and be familiar with basic techniques in molecular virology, cell biology and immunology. Research experience in SIV/HIV virology, innate immunology, SIV pathogenesis is highly desirable. Individuals with experience working with nonhuman primates are particularly encouraged to apply. Candidates must be authorized to work in the United States. The Center for Vaccine Research is housed in a state-of-art facility that has research programs focusing on AIDS and emerging infectious diseases and is part of a larger research community at the University of Pittsburgh that currently ranks sixth nationally in NIH funding. Interested individuals should submit a letter of application, curriculum vitae, and their name, address, e-mail and telephone number for three references to Cristian Apetrei, Center for Vaccine Research, University of Pittsburgh, 9044 BST3, 3501 Fifth Avenue, Pittsburgh, PA 15261. Tel: 412-624-3235. E-mail: apetreic@pitt.edu.
· E-mail preferred method of contact.
· Website: www.cvr.pitt.edu
The University of Pittsburgh is an equal opportunity, affirmative action employer. Women and minority candidates are strongly encouraged to apply.
Posted: March 4, 2010
Post-doctoral position in mast cell signaling and inflammation
A post-doctoral fellow position in mast cell signaling and inflammation is available in the laboratory of Andrew Craig at Queen’s University in Kingston, Ontario. The starting date is April 1, 2010, with an expected term of 3-4 years.
My lab is studying the molecular mechanisms governing mast cell activation and mediator release. We employ transgenic mouse models and cell-based models to define the functions of proteins involved in phosphotyrosine-based signaling mechanisms in mast cells ( http://qcri.queensu.ca/Craig.html).
For this project, the PDF will define the roles of F-BAR domain-containing proteins in mast cell activation. We have characterized the contributions of the F-BAR domain in membrane targeting and activation of FER protein-tyrosine kinase recently (McPherson et al. (2009) MCB 29:389-401), and plan to extend this work to a number of F-BAR-containing adaptor proteins that have not been previously studied in mast cells.
The applicant should be a highly motivated, recent Ph.D. graduate with expertise in molecular and cell biology, and excellent communication skill in English. Experience working with transgenic mice would be considered an asset.
Applicants should submit a CV with their publications and contact information for 2-3 referees via email to Dr. Andrew Craig (ac15@queensu.ca).
Posted: March 4, 2010
Postdoctoral position is available in the Unniraman lab in the Department of Immunology at Duke University Medical Center (Durham, NC) to study the mechanism of affinity maturation of antibodies by somatic hypermutation and class switch recombination. We use cell-line-based genetic screens to identify factors that target these mutagenic reactions to the antibody genes while ensuring the protection of the rest of the genome. You can get more details of our work at https://faculty.duhs.duke.edu/faculty/info?pid=29730.
An ideal applicant would be highly motivated with strong analytical skills. A strong background in molecular biology is required. Experience in BAC transgenics or library-based genetic screening is highly desirable. Start dates are flexible.
Applicants should email their CV and a summary of their research experience to Shyam Unniraman: shyam.unniraman@duke.edu.
Dr. Shyam Unniraman
Email:
shyam.unniraman@duke.edu
Address:Edwin L. Jones Bldg, Rm 312
Campus Box 3010
Dept of Immunology
Duke University School of Medicine
Durham, NC 27710
Phone: (919) 660-9003
FAX: (919) 684-8992
Posted: March 4, 2010
POSTDOCTORAL POSITIONS are available immediately at the Center for Vaccine Development (CVD) to join a multidisciplinary group of basic and translational researchers working to uncover the mechanisms underlying protective innate, cellular and antibody immune responses to a variety of microorganisms providing the rationale for new vaccine development and manipulation of host-pathogen interactions for disease prevention. Exciting new studies include exploration of the mechanisms operative in the generation of mucosal immunity in the gut microenvironment in humans and its relationship to the microbiota. These investigations are part of a recently awarded prestigious NIAID-funded Cooperative Center for Translational Research in Human Immunology and Biodefense (Sztein, P.I.). Studies include working with specimens obtained from children, adults and elderly subjects immunized with genetically engineered S. Typhi and Shigella vaccine candidates, as well as with malaria, hepatitis B, influenza and tularemia candidate vaccines. State-of-the-art immunological and molecular biology techniques (e.g., 14-color flow cytometry, gene expression microarrays, etc) are used to study antigen presentation, MHC-restriction, cloning and characterization of cytotoxic and helper T cells, identification of protective epitopes, role of dendritic and regulatory T cells, functional genomics, proteomics, systems biology and manipulation of cytokine production patterns to elucidate their role in the induction of innate, systemic and mucosal immune responses to vaccination and the mechanisms of immunosenescence.
The CVD offers a unique environment to study cellular and molecular determinants of protection to infectious diseases in humans. The CVD, largely supported by NIH funding and private foundations, has earned an international reputation for genetically engineering and testing vaccines against typhoid, shigella, cholera and malaria. Based at the School of Medicine, University of Maryland, Baltimore, the CVD was established in the mid-1970s as one of the first facilities to evaluate vaccines in community volunteers. It is one of only a handful of vaccine centers in the world engaged in the full range of vaccinology - from basic science through vaccine development, immunological studies, clinical evaluation and field studies.
The successful candidate should have a Ph.D. in Microbiology/Immunology or M.D. degree, experience in the study of immunological mechanisms, a strong publication track record, be highly motivated, have effective written and oral communication skills and hold a valid VISA to work in the US. Experience in flow cytometry and other CMI techniques, as well as molecular biology, functional genomics and/or tetramer technologies is highly desirable. Please send curriculum vitae, a brief outline of relevant research experience and interests and the names of three references via e-mail to Marcelo B. Sztein, M.D., Professor of Pediatrics; Leader, CVD Immunology Group; Chief, Cellular Immunology Section and Flow Cytometry Core Laboratory; CVD; University of Maryland at msztein@medicine.umaryland.edu. Further information about the CVD can be found at: http://medschool.umaryland.edu/CVD/. The UM is an affirmative action/equal opportunity employer.
Posted: March 4, 2010
A Postdoctoral Position in the Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, LA is available early May 2010. A highly motivated individual is sought to be involved in research efforts directed at examining the immune response against respiratory viruses including human metapneumovirus and respiratory syncytial virus using both cell culture and mouse model systems. The research projects will include studying the role of lung dendritic cells in viral pathogenesis. The department houses modern research laboratories enhanced by centralized PCR and microarray analyses, laser capture microdissection, fluorescence and electron microscopy, laser confocal microscopy, flow cytometry, proteomics, in vivo imaging, and BSL-3 laboratory suites.
Candidates must have a Ph.D. with previous experience in immunology, virology and /or molecular biology and possess excellent organizational skills as well as effective oral and written communications skills. Experience in working with animal models (mouse) is highly desirable.
Interested applicants should submit a copy of their C.V., a summary of research interest and contact information of three references to:
Antonieta Guerrero-Plata, Ph.D.
Department of Pathobiological Sciences
Louisiana State University
Skip Bertman Drive
Baton Rouge, LA 70803
E-mail: aguerrp@lsu.edu
http://www.vetmed.lsu.edu/pbs/guerrero-plata.htm
Louisiana State University is an equal opportunity employer. Women and minority candidates are strongly encouraged to apply.
Posted: March 4, 2010
Doctoral studies: Australian Postgraduate Research Award (Industry): “Retroviral invasion of the koala genome: prevalence, transmission and role in immunosuppressive disease”
Koala Infectious Diseases Research Group (KIDReG)
Faculty of Veterinary Science
University of Sydney
Mc Master Bldg B14
NSW 2006
AUSTRALIA
Damien Higgins BVSc, MVStud (Wild An Med Husb), PhD, Grad Cert Ed Stud
Senior Lecturer, Pathobiology and Wildlife Health
Ph
damienh@vetp.usyd.edu.au
DESCRIPTION: This scholarship is funded by an ARC Linkage-Projects grant and will provide support for 3 years on a full-time basis for a research project leading to a PhD. This study is based with the Koala Infectious Disease Research group in the Faculty of Veterinary Science, University of Sydney, and is in collaboration with the Koala Retrovirus (KoRV) research group at the University of Queensland, where prevalence and transmission of KoRV are being studied. There is considerable opportunity for work across both institutions. The aims of this part of the study are to investigate the effects of KoRV infection on the immune function of koalas and its potential role in disease arising from immune-suppression: an issue that has been of significant interest in the national and international press and has potential significance for the welfare and conservation of koala populations.
ELIGIBILITY: Applicants should have an Honours 1 or 2A degree in Veterinary Science, or a relevant Biological Science. Experience/background in immunology theory and methods would be an advantage. Ability and/or willingness to handle animals and work in the field for short periods would be an advantage. Applicants should have excellent English communication skills, be able to work independently and in a team, and be enthusiastic and self-motivated.
AMOUNT AWARDED: The scholarship stipend is $26,669 in 2010 (tax exempt). The scholarship does not cover any tuition fees payable by international students.
APPLICATION GUIDE: For further information, contact Dr Damien Higgins. email: damienh@vetp.usyd.edu.au Applications, including a curriculum vitae, copy of an academic transcript, and the names and contact details of at least two referees should be sent to Dr Damien Higgins, Faculty of Veterinary Science, Mc Master Building, B14, The University of Sydney NSW 2006. Email:
CLOSING DATE: Open until filled.
Posted: March 4, 2010
A postdoctoral fellow position is available to study immune response to flavivirus infection. The candidate should have PhD, MD, or equivalent degree within the last 2 years. Prior experience in cellular immunology, infectious pathogens and mouse model is preferred. Interested individuals are encouraged to send a cover letter with a statement of research interests, curriculum vitae, and names of three referees to Dr. Tian Wang, Dept. of Microbiology and Immunology, Univ. of Texas Medical Branch, Galveston, TX 77555-0609, USA. E-mail: ti1wang@utmb.edu.
Posted: March 4, 2010
Deeley Research Centre, BC Cancer Agency
This is a 3-year grant
funded fellowship. In this integral role, the Postdoctoral Fellow will
work under the general supervision of the Radiation Immune Research
Director and other investigators to study the effects of neo-adjuvant
hormone therapy and radiation therapy
on tumour-specific immune responses in prostate cancer. The project will
involve use of mouse models, as well as a prospective cohort of prostate
cancer patients who have participated in clinical and immunological
monitoring since 2004. The overarching goal is to understand how
treatment-induced antibody and T cells responses influence clinical
outcomes in prostate cancer, and how best to enhance these responses
therapeutically.
In addition to two years of related experience in experimental animal handling, a Ph.D in a related discipline such as Immunology, Biology, Microbiology, or Biochemistry is required. The successful candidate will have skills and experience in mammalian cell culture, general molecular biology techniques, immunoassays (cytokine, and cytotoxicity assays), flow cytometry, T cell biology and cell signalling pathways. An equivalent combination of education, training and experience will also be considered. The Postdoctoral Fellow will be able to work independently, and demonstrate excellence in conception, development and execution of a research project. Strong skills in scientific writing (grants, manuscripts) and oral presentation are required and the incumbent is expected to successfully attract funding during the fellowship. In addition, the successful candidate must be detail oriented, motivated and desire to work in a translational research environment
For more information about our centre, please visit: http://www.bccrc.ca/drc/. Applications can be submitted via email to:
Dr. Julian J. Lum
Deeley Research Centre. BC Cancer Agency-Vancouver Island Centre
2410 Lee Avenue
Victoria, BC, Canada; V8R 6V5
Email: jjlum@bccancer.bc.ca
Posted: March 4, 2010
Molecular immunology, T cell biology
T cell gene therapy in cancer & infectious disease
Are you wondering when your work will ever be used to help people? Apply for this opportunity to participate in translational research with a fast-track to human clinical applications.
With major funding to bring advanced concepts to Designer T Cell Therapies in Breast Cancer under DOD Breast Cancer Impact Award ($6 mil over 5 years), the Biotherapeutics Development Lab is seeking strong candidates for postdoctoral training. Join one of the few programs anywhere with direct clinical experience in gene therapies.
Subjects of lab research:
T cell receptor engineering
Co-stimulation engineering
T cell activation and anti-suppression strategies
Directed T cell trafficking
Retroviral vectorology
Animal models
Human clinical trials
Of particular interest are candidates with experience with:
T cell signaling pathways
Treg and tumor microenvironment suppressive mechanisms
T cell trafficking
Cytokine and chemokine biology
But candidates will be considered from a broad range of backgrounds. Please send resume, names of 3 references and summary of research interests to:
R. P. Junghans, Ph.D., M.D., Director, Biotherapeutics Development Lab, Associate Professor of Surgery and Medicine, Boston University School of Medicine, Chief, Division of Surgical Research, Roger Williams Medical Center, Providence, RI 02908 * Use the following email: cdeluca0@rwmc.org
Posted: February 22, 2010
University of Bretagne Occidentale Medical Center – U613
A 14-month post-doctoral position in the area of ion channel physiology and calcium signaling funded by the Region Bretagne is available immediately (February 2010) in the INSERM unit U613 located in the Medical Center of the University of Bretagne Occidentale in Brest (France).
This postdoctoral position is opened in the lab of Dr. Olivier Mignen to investigate the molecular and cellular mechanisms underlying calcium signaling in mammalian cells and its implication in Cystic fibrosis.
Our laboratory is mainly interested in understanding the molecular mechanisms underlying calcium entries in non excitable cells and their roles in health and disease. Calcium entry is essential for many cellular functions including gene expression, secretion, cell motility and cell proliferation and differentiation. We are investigating the molecular components and the control mechanisms of store dependent and store independent calcium entries.
The main objective of the project is to characterize in airway epithelial cells the calcium signaling pathways involved in ion secretion and the potential beneficial roles of their stimulation to counteract the defect of chloride secretion observed in cystic fibrosis. The postdoctoral scientist will also be involved in studies designed to identify protein partners of calcium channels involved in calcium entry and pharmacological modulators of these entries. The knowledge derived from our research may ultimately lead to design novel pharmacological agents to treat Cystic fibrosis. Our project combines different experimental approaches including live-cell imaging, biochemistry, molecular biology and electrophysiology.
Extremely motivated Ph.D.s (maximum of 3 years postdoctoral experience) with a strong background in molecular and cell biology are encouraged to apply. Candidates with demonstrated records in studying calcium signaling will be preferred. Experiences in electrophysiology would be an asset but is not required. The candidate should have proven skills in Western blotting, immunoprecipitation, real time PCR, immunofluorescence, immunohistochemisty, cell culture techniques and in vitro transfection. Additional preferred skills include live cell confocal microscopy and proteomics. Knowledge of the physiology of fluid-secreting epithelia will also be appreciated. The applicant must be enthusiastic with communication skills (English and/or French) in order to be able to join a young starting team located in an excellent environment of research with various state-of-the-art core facilities. The applicant will collaborate with the other members of the unit and must show a high motivation interdisciplinary work.
Salary ~ 2000€/month.
Interested applicants should send a letter of application, curriculum vitae and the names, telephone numbers and e-mail addresses of three references by e-mail to: olivier.mignen@univ-brest.fr.
Please
also indicate in your application:
1. your particular knowledge and enthusiasm regarding the topic and
interest in this project - this is very important
2. your availability
3. your email address (for acknowledgements of applications)
4. three names for letters of recommendations
For addition questions and information:
Olivier Mignen
INSERM U613 - IFR148 ScInBioS
Faculté de Médecine et des Sciences de la Santé
22 avenue Camille Desmoulins
F-29200 BREST -FRANCE
tel.: + 33 (0)2 98 01 67 05
fax. : + 33 (0)2 98 01 82 29
e-mail:
olivier.mignen@univ-brest.fr
visit our webpage:
http://www.genetic-brest.fr/
Posted: February 16, 2010
Post-Doctoral Position in Molecular and Cellular Immunology
There is an immediate opening for a highly motivated and passionate PhD, MD/PhD or MD to investigate the Immunobiology of Lyme Disease initiated by Borrelia burgdorferi infection in the human setting. The work will involve molecular and cellular characterization of the T cells mobilized during infection including their antigen recognition properties and effector/regulatory functions. Prior training experience in molecular and cellular immunology would be an asset. The individual will have access to state of the art core facilities and be part of a team using a systems biology based approach to this novel and complex disease. Please send, via email or mail, current complete c.v. and names/contact information of three references to: Mark J. Soloski, Ph.D., Division of Rheumatology, Johns Hopkins School of Medicine, 5200 Eastern Avenue, Mason Lord Building, Center Tower, Suite 6000, Rm 677, Baltimore, MD 21224 (mski@jhmi.edu).
Posted: February 16, 2010
The main focus of my lab is the interactions between host immunity and bacteria, mediated by pattern recognition receptors (PRRs). I am looking for a motivated candidate to join my lab and study the interactions between host immunity and oral commensals in dental diseases, which is supported by NIH funding. During last several years, our understanding of host responses against pathogens, and immunoregulatory roles of microflora have been greatly advanced. We would like to answer several interesting questions including how hosts control commensal colonization, and how the host/commensal interactions affect the diseases. This research project includes functional analysis of genetically altered mice in disease models and in vitro assays. The successful candidate should have a PhD with experience in immunology and the ability to develop skills in molecular biology and microbiology. The starting date is flexible and can be between March 1 and June 1st, 2010.
Please indicate a preferred means for interested applicants to contact you or a designated contact person:
E-mail to ino@umich.edu (Naohiro Inohara).
Naohiro Inohara
Research Associate Professor
Department of Pathology
University of Michigan Medical School
MSRB2 C574
1150 W. Medical Center Dr.
Ann Arbor, MI 48109
Phone 734-615-7080
Fax 734-647-9654
ino@umich.edu
Posted: February 16, 2010
We have a position available for an outstanding postdoctoral fellow with strong expertise in cellular and molecular immunology and an excellent publication record in internationally renowned journals. The successful candidate will use our unique mouse models and cell based assays to analyze the functions and molecular mechanisms of action of novel genes in lymphocyte development and function. In particular, the candidate will investigate the functions of selected genes in swine-flu or LCMV infections and pathology. For more details, see Science 316, 886-889 (2007), Molecular Cell 33, 43-52 (2009), Science 324, 1569-1572 (2009) and www.scripps.edu/ims/sauer.
Requirements: Substantial expertise in relevant techniques, such as analyses of responses to LCMV or Influenza virus infections in mouse models, analyses of immune system development or peripheral lymphocyte function in mouse models, RNAi studies in mice or tissue culture cells, retro- and lentiviral transduction techniques, biochemistry, in vivo and in vitro assays for CD4 effector/memory T cell, TH1/2/17, Treg or cytotoxic CD8 T cell function. Proven expertise in analyzing cytokine, effector and memory responses to chronic or acute viral infections will be a particular advantage. In addition to outstanding scientific credentials, very strong work ethics and a proven ability to work independently with minimal supervision, the successful candidate will have a pleasant, friendly personality and enjoy working in a fast-paced environment. S/he will have an excellent, fluent oral and written command of the English language and enjoy to actively participate in scientific discussions in a challenging and stimulating research environment.
If you are interested in joining us, please submit your CV, a brief outline of your research interests and a list of at least three references to ksauer@scripps.edu.
Karsten Sauer, Ph.D.
Department of Immunology and Microbial Science
The Scripps Research Institute (TSRI)
Room R219, Mail Stop IMM-24
10550 North Torrey Pines Road
La Jolla, CA 92037, USA
Phone: +1 (858) 784-7397
Fax: +1 (858) 784-7422
Email: ksauer@scripps.edu
Webpage: www.scripps.edu/ims/sauer
Posted: February 16, 2010
A postdoctoral research position is available in the laboratory of Drs. Richard Dutton and Susan Swain.
The position will be available in the Department of Pathology at the University of Massachusetts School of Medicine at Worcester, MA starting June 1, 2010 (but earlier or later start dates are possible).
The successful candidate will study the generation, persistence and function of memory CD8 T cell subsets with special reference to the roles of different polarized subsets, Tc1 Tc2 and Tc17 and their multiple effector functions, using a mouse model of influenza infection.
Requirements:
A Ph.D. in Immunology, Microbiology and/or Molecular Biology, a demonstrated graduate studies record of scientific accomplishment, a desire to study the underlying cellular and molecular mechanisms of T cell differentiation following infection and an interest in host pathogen interactions. Hands on experience with in vivo and in vitro mouse models is desirable.
Excellent written and oral communication skills in English.
Please send curriculum vitae, addresses of three references and a letter describing your research interests to: Richard Dutton, Trudeau Institute, Inc., 154 Algonquin Avenue, Saranac Lake, NY 12983 or e.mail at rdutton@trudeauinstitute.org.
Posted: February 16, 2010
A postdoctoral position at the Burnham Institute for Medical Research, La Jolla, CA, is available immediately to study the regulation of the generation, homeostasis, and responses of memory T cells in the immune response to influenza viruses by CD44 and the selectin family of adhesion receptors. We use TCR transgenic CD4 and CD8 T cells and cytokine reporter mice to track and profile Ag-specific T cells in an influenza model using cellular and molecular approaches with knockout and transgenic animals.
Applicants must have a Ph.D. or M.D. degree with a strong background in immunology. Experience with murine models, flow cytometry, biochemical, and molecular techniques is required. Qualifications must also include strong interpersonal skills, excellent communication (both written and oral) and organizational skills, an ability to work independently, and commitment to laboratory research.
The Sanford Burnham Medical Research Institute has state of the art facilities in flow cytometry, imaging, genomics, proteomics, and high throughput screening. The institute is located on the Torrey Pines Mesa that is home to a broad base of immunology research in both academic and biotech sectors.
Applicants should send a CV, statement of research interests, and names of 3 references to:
Linda M. Bradley, Ph.D.
Professor
Infectious and Inflammatory Diseases Center
Sanford Burnham Medical Research Institute
10901 N Torrey Pines Rd B-12
La Jolla, CA 92037
email: lbradley@burnham.org
tel: 858 795 5121
Posted: February 16, 2010
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Postdoctoral position in transplant
and cancer immunology at the University of Chicago Our lab is interested in studying the regulatory pathways for tumor evasion and genesis, particularly focusing on a subset of the TNF receptor family and the role of regulatory T cells in this setting. Particularly, we are studying signaling pathway(s) that link Treg and the innate immune cellular components which mediate tumor immunity and tolerance, and the impact of Treg migration and localization in mediating inflammation and tumor growth. The position is intended for exceptional candidates with an MD, Ph.D., or M.D/PhD, who has excellent graduate training and a record of publications in immunology/molecular biology/cancer biology. Experience in innate immunity and T-cell biology, molecular biology, cancer models, optical or multiphoton imaging, and in vivo mouse models is highly desired. |
Postdoctoral position in gut mucosal
and transplant immunology at University of Chicago Our lab has two major interests: studies of the post-thymic development and localization of regulatory T cells (Treg), and the impact of gut microflora in mediating innate and adaptive immune responses which lead to graft-versus-host disease following stem cell transplantation. Post-thymic Treg development and homing: Effective immune responses require migration of T cell subsets with homing specificity to distinct tissue locations. We are studying the post-thymic development and acquisition of homing receptors on Treg, and how their specific migration controls tissue and organ-specific immunity in models of inflammation and leukemia/lymphoma, as well as using human samples and xenogeneic systems. The goal of this research is to develop targeted molecular and cellular treatment strategies that separate graft-versus-host disease from the beneficial graft-versus-tumor reaction following hematopoietic stem cell transplantation. Tissue tropism in graft-versus-host disease: Acute graft-versus-host disease (aGvHD) targets the epithelial compartments of the intestine, liver, and skin. Although it is known that the adaptive immune response toward the genetic mismatch of the donor-recipient pair is crucial for the induction of aGvHD, it remains unclear why tissue tropism for the intestine, skin, and liver occurs. Significant commensal bacteria load exists in the intestine and the skin, while the liver continuously filters antigens derived from the gastrointestinal tract. Our lab is investigating the microflora niche and its role in mediating the local immune milieu which leads to tissue specific aGvHD. The position is intended for exceptional candidates with an MD, Ph.D., or M.D/PhD, who has excellent graduate training and a record of publications in immunology/molecular biology/cancer biology. Experience in innate immunity and T-cell biology, molecular biology, cancer models, optical or multiphoton imaging, and in vivo mouse models is highly desired. |
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Interested applicants should email their curriculum vitae, a statement
of current and future research interests, and complete contact
information of three references to: Dr. Vu Nguyen, Division of Biological Sciences, University of Chicago, vnguyen@medicine.bsd.uchicago.edu Posted: February 16, 2010 |
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Postdoctoral Position: Host-Pathogen Interactions A postdoctoral research position is available in the laboratory of Dr. Liselotte E. Jensen ( http://www.med.upenn.edu/pharm/faculty/jensen/jensen.html). Anticipated start date is July 1st, 2010; however, the position will remain open until a suitable candidate is identified.The highly motivated successful applicant will study the role of innate immune mechanisms during viral and bacterial infections of the skin. Experimental models will include in vitro assays, tissue culture and knockout/transgenic mouse models. The study aims to identify novel regulatory mechanisms of signal transduction. Requirements: • A Ph.D. in Immunology, Microbiology and/or Molecular Biology.• Peer-reviewed publications in the field(s) of Immunology, Microbiology and/or Signal Transduction.• Experience with molecular biology, biochemistry, immunology, histology, signal transduction, cell culture methods and animal handling (mice) and breeding.• Excellent written and oral communication skills in English.Additional experience with in vivo infection models and vaccine development is highly desirable.
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Postdoctoral Position: Innate immune mechanisms in
skin and role in chronic inflammation A postdoctoral research position is available in the laboratory of Dr. Liselotte E. Jensen ( http://www.med.upenn.edu/pharm/faculty/jensen/jensen.html). Anticipated start date is July 1st, 2010; however, the position will remain open until a suitable candidate is identified.The successful candidate will be highly motivated to study innate immune mechanisms involving keratinocytes during chronic inflammation of the skin. Links to cardiovascular disease, asthma and arthritis may be explored. Experimental models will include in vitro assays, microarray screening, tissue culture and knockout/transgenic mice. Requirements: • A Ph.D. in Immunology, Cell Biology and/or Molecular Biology.• Peer-reviewed publications in the field(s) of Immunology, Skin Physiology/Pathology and/or Signal Transduction.• Extensive documented hands-on experience with molecular biology, biochemistry, immunology, histology, signal transduction, cell culture methods, animal handling (mice) and breeding.• Excellent written and oral communication skills in English.Candidates with additional experience with in vivo models of skin inflammation, working with clinical human samples and isolation of primary keratinocytes will receive priority evaluation. |
| Send
cover letter, statement of research interests, CV and contact
information for 3 references to:
Liselotte E. Jensen, Ph.D., Department of Pharmacology, University of Pennsylvania, 89 John Morgan Building, 3620 Hamilton Walk, Philadelphia, PA 19104-6084. E-mail: liselott@mail.med.upenn.edu Posted: February 5, 2010 |
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A postdoctoral position is available immediately in the Chang laboratory at the University of California, San Diego. The laboratory is focused on understanding the potential role of asymmetric division in T cell differentiation into effector and memory subsets (J.T. Chang, S.L. Reiner, Science 2007). More information about the laboratory’s research interests can be found at http://changlab.ucsd.edu. The successful candidate will gain experience in (1) developing multi-disciplinary approaches towards understanding T cell differentiation and fundamental mechanisms of asymmetric cell division and (2) developing cutting edge techniques in molecular and cellular immunology, flow cytometry, and confocal microscopy.
We are seeking highly motivated candidates with a M.D. or Ph.D., with experience in techniques such as flow cytometry, molecular cloning, tissue culture, microscopy, animal models of disease, and biochemistry. Prospective candidates should be highly motivated individuals with excellent communication/interpersonal skills, and have the ability to work independently.
Candidates are encouraged to send a cover letter with a statement of research interests, curriculum vitae, including publication list, and names and e-mail addresses of three referees to Dr. John Chang by email: changj@ucsd.edu.
Posted: February 4, 2010
A postdoctoral position in The Madrenas
laboratory is immediately available to study mitochondrial biogenesis and
function in the context of mouse and human T cell activation, using
cutting-edge, in vivo and in vitro genetic, biochemical, and
pharmacological approaches. Recent publications representative of our work
are: Immunity 2006; 25: 67, Annu Rev Immunol
2006; 24: 65, Nature Medicine 2009; 15: 641,
Cancer Cell 2009; 16: 161.
The Madrenas Laboratory is one the laboratories within the
Centre for Human Immunology at The University of Western Ontario, a member
of the International Network of Centres of Excellence in Clinical
Immunology (http://www.robarts.ca/madrenas).
The Centre houses an impressive group of laboratories working in
different areas of basic and clinical immunology, with access to advanced
core facilities. We provide competitive salary and excellent benefits in a
rewarding and multidisciplinary environment. If interested, please send a
curriculum vitae, a statement of research accomplishments and career
goals, and the names of three references (including telephone and email)
to Dr. J. Madrenas, Robarts Research Institute, P.O. Box 5015, 100
Perth Drive, London, Ontario, Canada N6A 5K8,
madrenas@robarts.ca.
Posted: February 4, 2010
Our research institute (www.trudeauinstitute.org) is currently seeking a highly motivated researcher for an immediate opening in the laboratory of Dr. Erika Pearce. Applicant must have a Ph.D. in the field of immunology and/or molecular and cellular biology, a demonstrated graduate studies record of scientific accomplishment, and motivation to study the underlying cellular and molecular mechanisms of T cell differentiation during infection. Project emphasis will be on establishing how changes in cellular metabolism regulate T cell memory development and immune function (see publication in Nature, 2009, 460, 103-107).
Trudeau Institute, Inc. is a not-for-profit biomedical research institute with state-of-the-art facilities and an international reputation for excellence. Located in the heart of New York State's Adirondack Mountains overlooking beautiful Saranac Lake, Trudeau offers competitive salaries and benefits, including daycare and housing as well as a generous retirement plan. Rated among the top 3 "Best Places to Work" for scientists and postdoctoral fellows by The Scientist.
Please send curriculum vitae, addresses of three references and a letter describing your research interests to: Amy Richardson, Human Resource Manager, Trudeau Institute, Inc., 154 Algonquin Avenue, Saranac Lake, NY 12983 Arichardson@trudeauinstitute.org.
Posted: February 4, 2010
POSTDOCTORAL POSITION IN IMMUNOLOGY AT SAN DIEGO
STATE UNIVERSITY
A position is available for an individual interested
in age-associated alterations in innate immune responses to viral
infections. The focus of the project is on dendritic cell migration and
interaction with T cells. PhD. or equivalent degree is required.
Previous experience in immunology and/or virology
required. Screening will continue until successful candidates
are identified or the search is closed. SDSU is an Equal
Opportunity/Affirmative Action Employer.
Investigator: Phyllis-Jean Linton
E-mail Address:
plinton@sciences.sdsu.edu
Postal Address: Bioscience Center – mail drop 4650, SDSU, 5500 Campanile
Dr., San Diego, CA 92182-4650
Posted: January 29, 2010
A postdoctoral position is immediately available to study organ transplantation immunology in the laboratory of Dr. Kupiec-Weglinski, http://dgsom.healthsciences.ucla.edu/research/institution/personnel?personnel%5fid=46959, at the Dumont-UCLA Transplant Center in Los Angeles. Research focus will be on the molecular and cellular mechanism of acquired immunological tolerance in a murine cardiac allograft model. The ideal candidate will have experience working with T lymphocytes in vitro and in vivo, be capable of establishing independent research projects, possess excellent English communication skills, work well with scientific colleagues from diverse backgrounds, and already be eligible to work in the United States.
To apply: Interested candidates should submit a CV, a cover letter outlining research interests, and three references. Applications should be submitted by email to the PI at: jkupiec@mednet.ucla.edu.
Posted: January 29, 2010
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RESEARCH FELLOW in immunology – position
immediately available in Singapore Immunology Network (SIgN) One Postdoctoral Position is immediately available at Singapore Immunology Network (SIgN), Singapore, in the group headed by Prof. Paola Castagnoli. SIgN is one of the research institutes of the Agency for Science, Technology & Research (A*STAR) located at Biopolis, the epicentre of biomedical research in Singapore, with the aim to build up a strong program in human immunology research with an emphasis on infection and inflammation studies. We are looking for a highly motivated individual to study in innate immunity the role of dendritic cells during bacterial and viral infections. Applicants must have a Ph.D. or M.D., a solid background in Immunology and Molecular Biology and a track record of accomplishments. Ability in taking initiative and work independently is essential. Experience in cellular and molecular immunology, flow cytometry, tissue culture techniques, murine models of disease and transgenic/knock-out mouse-related work is highly desired. We offer an international research environment of 150-200 researchers with a leading biomedical and immunological research. Salary is highly competitive based on experience, plus a comprehensive benefit package. Interested applicants should send a copy of their resume with publication list, one page of summary of research experience and interests, and contact information of three referees who could be contacted for letters of reference to: |
RESEARCH FELLOW in immunology – position
immediately available in Singapore Immunology Network (SIgN) One Postdoctoral Position is immediately available at Singapore Immunology Network (SIgN), Singapore, in the group headed by Prof. Paola Castagnoli. SIgN is one of the research institutes of the Agency for Science, Technology & Research (A*STAR) located at Biopolis, the epicentre of biomedical research in Singapore, with the aim to build up a strong program in human immunology research with an emphasis on infection and inflammation studies. We are looking for a highly motivated individual to study in innate immunity the role of NLRP3 inflammasome pathway. Applicants must have a Ph.D. or M.D., a solid background in Immunology and Molecular Biology and a track record of accomplishments. Ability in taking initiative and work independently is essential. Experience in cellular and molecular immunology, flow cytometry, tissue culture techniques, murine models of disease and transgenic/knock-out mouse-related work is highly desired. We offer an international research environment of 150-200 researchers with a leading biomedical and immunological research. Salary is highly competitive based on experience, plus a comprehensive benefit package. Interested applicants should send a copy of their resume with publication list, one page of summary of research experience and interests, and contact information of three referees who could be contacted for letters of reference to: |
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Ms Peggy Leong, Personal Assistant
to Prof. Paola Castagnoli, Senior Administrative Executive, Singapore
Immunology Network (SIgN), 8A Biomedical Grove, IMMUNOS Bldg, Level
4,Singapore 138648;
peggy_leong@immunol.a-star.edu.sg; +65 6407 0064 (office); Fax: +65
6464 2057 Posted: January 29, 2010 |
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Post Doctoral / Research Scientist position in Singapore
The Singapore General Hospital is the largest acute care hospital in Singapore and is the teaching hospital associated with the Duke-National University of Singapore Graduate Medical School. A post-doctoral/research scientist position is available in the Department of Clinical Research to study the role of T lymphocytes in the pathogenesis of autoimmune diseases. The successful candidate will be part of a multi-institutional group with expertise in rheumatology, immunology, stem cell biology, and health services research.
We are looking for interested candidates with a Ph.D. in immunology, with experience in techniques, such as flow cytometry, ELISA, real time PCR, tissue culture and immunohistochemistry. The candidate must have the ability to work independently, present work at scientific meetings, and a good publication record. The candidates must also demonstrate a commitment to research, excellent communication skills, and a desire to learn novel techniques.
The position is funded by the National Medical Research Council and is available from April 2010 for up to 3 years. Enquiries may be directed to Ms. Joanne Lim at email: Joanne.lim.b.p@sgh.com.sg or Ms. Elaine Tan at email: elaine.tan.b.l@sgh.com.sg.
Posted: January 26, 2010
Research Associate/Postdoctoral Position
Dartmouth Medical School
A Research Associate/postdoctoral position is available in Tumor Immunology. This position is available for a scientist interested in immunotherapy of cancer. The project will focus on the use of novel chimeric receptors to target tumors and involve investigating their function in murine models and with primary human tumors. The appropriate person will have a background in molecular, cellular and/or in vivo techniques. Good communication skills and ability to work in a team are essential. Salary will be commensurate with experience.
Please send curriculum vitae, list of publications, and the names of three references to:
Dr. Charles Sentman
Department of Microbiology and Immunology
Dartmouth Medical School
6W Borwell Bldg
One Medical Center Drive
Lebanon, N.H. 03756
tel: 603 650-8007
email:
charles.l.sentman@dartmouth.edu
website:
http://dms.dartmouth.edu/faculty/facultydb/view.php?uid=139
Posted: January 25, 2010
Vaccine & Gene Therapy Institute, Port St. Lucie, Florida
We seek a highly skilled and motivated post-doctoral scientist with background in human immunology. We welcome highly motivated post doctoral fellows with interest and experience in molecular and cellular immunology to join the laboratory of Dr. Elias Haddad at the Vaccine and Gene Therapy Institute in Florida (VGTI-Florida) to study memory T and B cells in chronic diseases. Prior experience in B cell biology is required. Experience in T cell biology is a plus. VGTI-Florida houses a highly interactive group of scientists performing state-of·the-art basic and applied research on infection and immunity with expertise in virology, immunology, cell biology, and animal models. Our scientists study AIDS pathogenesis and vaccine development, infection and immunity of aged and other vulnerable populations. Prevention and treatment of herpes family viral diseases. Prevention and treatment of diseases mediated by bioterrorism agents and emerging pathogens.
Requires: Ph.D. in a biosciences, related lab experience.
Apply online at www.OHSUjobs.com, reference IRC29417.
Posted: January 22, 2010
Postdoctoral Position in Immunology
Available immediately to study T regulatory cells in multiple sclerosis. The applicant must have recently completed a PhD or equivalent in Immunology, Biochemistry, Molecular Biology, Genetics, or a related field. The ideal candidate will have expertise in flow cytometry, tissue culture, molecular biology, mouse handling, and an interest in cytokine signaling and epigenetic mechanisms of gene regulation. The successful candidate will be joining a young, dynamic environment within the Center for Cellular and Molecular Immunology at the University of Missouri in Columbia.
Interested applicants should send a cover letter, CV, summary of previous research experience, and three letters of references to Dr. Susan McKarns @ mckarnss@health.missouri.edu.
Posted: January 19, 2010
Interested applicants should send a CV, cover letter expressing interests and long-term career goals, and contact information for three references by email to:
Yingzi Cong, Ph.D.,
Associate Professor of Microbiology, Immunology, and Pathology
yicong@utmb.edu or ycong@uab.edu
Posted: January 15, 2010
Turn talent into success with Baylor Health Care System. Over a century of being the best – for patients, families and our community. We're Baylor Health Care System (BHCS), a multi-hospital, not-for-profit organization that is setting the standard for health care excellence in the Dallas/Fort Worth Metroplex. Baylor has achieved a number of honors, including being ranked in U.S News & World Report's "America's Best Hospitals"; nursing Magnet status for Baylor University Medical Center and Baylor Heart and Vascular Hospital; Consumer Choice Award for Overall Quality and Image; Health Care's "Most Wired" hospitals; and the Dallas Business Journal’s Best Places to Work.
Post-Doctoral
Fellow
Immunology Research
The Baylor Institute for Immunology Research (BIIR) is among the top immunological, basic, science research centers in the world. Scientists at BIIR particularly concentrate most of their efforts on the study of dendritic cells, rare cells that turn on and regulate immune responses with the goal of bringing relief to diseases involving the immune system.
We currently have an opening for a Post-Doctoral Fellow. Under the general supervision of the BIIR Director and the sponsorship of a BIIR Investigator, the Post-Doctoral Fellow will develop and work on a mutually agreed upon project that promotes the research goals of BIIR. The Fellow will periodically present seminars on his/her original work in progress and make informative presentations on scientific articles at Journal Club. The position of Post-Doctoral Fellow is designed to be of two to three years’ duration, with the goal of developing young scientists into independent investigators. The process focuses on honing skills to design and implement a research strategy and effectively present his/her data in verbal and written media for the purpose of obtaining grants and scientific publications. A Post-Doctoral Fellow may be promoted to a Senior Post-Doctoral Fellow once he/she has achieved data worthy of publication and has presented such at a BIIR Works-in-Progress Seminar. The promotion must be approved by both his/her Investigator and the BIIR Director.
The Baylor Institute for Immunology has raised funds to strongly support preclinical non-human primate (NHP) studies of novel influenza and human papillomavirus vaccines based on targeting antigens directly to dendritic cells. We are seeking a skilled and highly motivated individual to characterize in fine detail T cell responses in the vaccinated animals, primarily using frozen PBMCs. Previous experience with characterization of human or NHP T cell responses via peptide-stimulated proliferation, cytokine secretion, intracellular cytokine accumulation, and T cell surface markers is essential. Skill sets must include tissue culture, blood cell purification, cell sorting and flow cytometry. The required tasks are at the cutting edge of vaccine development and thus the position is highly suited for a Post-Doctoral Fellowship or an experienced Technician. The ideal candidate will be a superior writer, superb presenter and exceptional organizer.
Requirements: If you have a Doctorate degree, at least two years’ residency, 3 years of experience and are a Doctor of Medicine, consider joining Baylor.
Join Baylor: Explore a system of rewards and unmatched opportunities with health care's brightest minds.
Apply online at www.baylorhealth.com/careers or contact James Smyda at James.Smyda@baylorhealth.edu or 214-820-8303.
EOE
Posted: January 15, 2010
Post-doctoral fellow position in ocular immunology with Dr. Sharmila Masli is available at Schepens Eye Research Institute, an affiliate of Harvard Medical School, to study immunological mechanisms underlying ocular inflammatory diseases and molecular mechanisms involved in immunologic tolerance induction. Candidates with experience in mouse surgery, working knowledge of flow cytometry and associated data analysis, immunohistochemistry and molecular biology techniques will be preferred. The successful applicant will have publications in the areas of Ophthalmology or Immunology.
Interested candidates are invited to send their CV, a cover letter of introduction, and three references with contact information to sharmila.masli@schepens.harvard.edu. For more information about the Institute visit: www.schepens.org.
Posted: January 11, 20
10The ideal candidate will have experience working with Schistosoma or other parasites, be capable of establishing independent research projects, possess excellent English communication skills, work well with scientific colleagues from diverse backgrounds, feature a strong publication record in microbiology and/or immunology, and already be eligible to work in the United States. Candidates with their own fellowship funding are highly desirable.
To apply: Interested candidates should submit a c.v., cover letter outlining research interests, three references, and up to five article reprints. Applications should be submitted by email to the PI at: mhhsieh@stanford.edu.
Posted: January 6, 20
10Exciting projects are available for the highly motivated candidate who has recently received his/her training in molecular and cellular biology. Candidates should own a background in immune system development, and experience in working with gene knockout mouse husbandry. Applicants with stem or iPS cell culture experience have a plus. We offer an interactive research environment in a multidisciplinary research department with a leading biomedical and immunological research team. Salary is based on experience, plus a comprehensive benefit package. Interested individuals should send a cover letter, resumes, and names of 2 or 3 individuals who could be contacted for letters of reference to Dr. Dong-Ming Su (Associate Professor), Email: dmsu2003@yahoo.com or Fax #903-877-7968.
Posted: January 6, 20
10Location: University of North Carolina School of Medicine, Thurston Arthritis Research Center, Chapel Hill, NC
Department Name: Medicine
Position: Post-doc
Description: An immunology postdoctoral position is available for a M.D. or Ph.D. level candidate interested in studying the molecular determinants regulating chemokine receptors and cellular trafficking in inflammatory disease models. Our laboratory is based in the Thurston Arthritis Research Center and is interested in understanding how cells migrate abnormally in inflammatory conditions such as atherosclerosis, arthritis, and metastasis. For more information, please visit: http://tarc.med.unc.edu/research_tarrlab.php.
Requirements: Ph.D. or M.D. or anticipation of either degree in the spring of 2010. Non-U.S. citizens will be most competitive if they have at least 1 year of experience as a post-doc in the USA or have received their Ph.D. in the U.S., Europe or Japan.
Start Date: Flexible
Application Instructions: Please send curriculum vitae and contact information of three references to: Dr. Teresa Tarrant, M.D. University of North Carolina School of Medicine at Chapel Hill, Division of Rheumatology, Allergy, and Immunology, CB# 7280 Chapel Hill, NC 27599. Phone: 919-843-4727.
I prefer contact through email: teresa_tarrant@med.unc.edu.
Posted: January 6, 20
10Harvard Medical School/Brigham and Women’s Hospital
Cutting edge projects focusing on the mechanisms of autoimmune disease/inflammation. These projects include novel pathways that regulate macrophage biology linked to photosensitive autoimmune cutaneous lupus, intrinsic and macrophage mediated mechanisms of autoimmune kidney injury and repair, the power of specific programmed death pathways in regulating macrophage mediated autoimmune cardiac injury, and an emphasis on the role of resident cells regulating harmful immune response. A wealth of unique transgenic and knockout mice have been constructed on lupus-susceptible strains for these projects. These projects dissecting the basic mechanisms of autoimmune disease (kidney, skin and heart) have human translational projects and potential therapeutic target applications.
Experience:
Immunology, Molecular biology and/or Cell Biology
Knowledge of histopathology desirable
Mouse and human systems
Computer literacy is necessary
Desired:
Responsible, hard-working individual who is able to multi-task and to work independently
M.D. or Ph.D. required, position for two years or longer within the Department of Medicine, Brigham and Women’s Hospital.
Please send three references.
Interested candidates contact: Dr. Vicki Rubin Kelley, Harvard Institutes of Medicine, 4 Blackfan Circle, Boston, MA 02115; e-mail: vkelley@rics.bwh.harvard.edu.
Posted: January 4, 20
10FDA Commissioner’s Fellowship Program
Touch the Lives of All Americans! The FDA Commissioner’s Fellowship Program is a two-year training program designed to attract top-notch health professionals, food scientists, epidemiologists, engineers, pharmacists, statisticians, physicians and veterinarians. The Fellows work minutes from the nation’s capital at FDA’s new state-of-the-art White Oak campus in Silver Spring, Maryland or at other FDA facilities. The FDA Commissioner’s Fellowship offers competitive salaries with generous funds available for travel and supplies.
Coursework & Preceptorship -- The FDA Commissioner’s Fellowship program combines coursework designed to provide an in-depth understanding of science behind regulatory review with the development of a carefully designed, agency priority, regulatory science project.
Who Should Apply? Applicants must have a Doctoral level degree to be eligible. Applicants with a Bachelor’s degree in an Engineering discipline will also be considered. Candidates must be a U.S. citizen, a non-citizen national of the U.S., or have been admitted to the U.S. for permanent residence before the program start date. For more information, or to apply, please visit: www.fda.gov/commissionersfellowships/default.htm.
Applications will be accepted from December 15, 2009 – April 15, 2010.
Posted: December 23, 2009
POSTDOCTORAL POSITION IN IMMUNOLOGY AT BROWN UNIVERSITY
A position is available for an individual interested in innate immune responses to viral infections. Focus of the project is on regulation of signaling responses to cytokines and natural killer cells. Ph.D. or equivalent degree is required.
Previous experience in immunology, virology, biochemistry, or molecular biology required. Please send curriculum vitae, and have 3 letters of references sent, to: Dr. Christine A. Biron, Division of Biology and Medicine, Department of Molecular Microbiology and Immunology, Box G-B629, Brown University, Providence, RI 02912. Screening will continue until successful candidates are identified or the search is closed. Brown University is an Equal Opportunity/Affirmative Action Employer.
Investigator: Dr. Christine A. Biron
Email Address:
Christne_Biron@brown.edu
Postal Address: Division of Biology and Medicine, Department of Molecular
Microbiology and Immunology, Box G-B629, Brown University, Providence, RI
02912. Phone: 401 863-2921. Fax: 401 863-1971.
Web:
http://www.research.brown.edu/research/profile.php?id=1100923723&r=1
Posted: December 23, 2009
Postdoctoral Fellowships in Immunology/Cellular Signaling
St. Jude Children’s Research Hospital
Department of Immunology
Postdoctoral Fellowships are available at St. Jude Children’s Research Hospital to investigate cellular signaling in the immune system. We are particularly interested in dissecting the signaling pathways mediated by the kinases mTOR and MAPK and the sphingosine 1-phosphate (S1P) receptors in basic T cell and dendritic cell biology. We also investigate molecular mechanisms of autoimmune and infectious diseases (multiple sclerosis, colitis, lupus and Listeriosis). The experimental models include genetically-modified mice and primary immune cells derived from these mice. Please see the following articles (Nature Immunology 10:769, 2009; Nature Immunology 8:1236, 2007; PNAS 103: 2274, 2006; and Nature Immunology 7: 851, 2006) and the website (www.stjude.org/chi) for additional information.
St. Jude Children’s Research Hospital, a private, non-profit research institute, located in Memphis, Tennessee, USA, offers a stimulating, highly collaborative research environment with state-of-the-art research resources, along with competitive salary and excellent benefits to postdoctoral fellows.
Highly motivated individuals with a recent Ph.D. in immunology, biochemistry, or cellular and molecular biology, with evidence of scientific accomplishment, are encouraged to apply. Please send curriculum vitae including a list of three references to: Dr. Hongbo Chi (hongbo.chi@stjude.org).
St. Jude is an Equal Opportunity Employer and a Drug Free Workplace.
Posted: December 18, 2009
Posted: December 16, 2009
Protumoral role of monocytes/macrophages and their use in gene therapy
Recent studies using transgenic models and tumor transcriptome profiling have provided convincing evidence for linking inflammation and cancer. One particular inflammatory cell, the monocyte/macrophage, has emerged as a central regulator of tumor onset and progression. Indeed, monocytes/macrophages represent the major proportion of the host-derived immune cells associated with most solid tumor and their recruitment/activation at these sites are largely regulated by tumor-derived signals like chemokines, cytokines and endogenous signals (e.g CCL2, VEGF, MCSF, TNF, IL-1β, angiopoietins, necrotic debris). We and others have shown that tumor-associated macrophages (TAM) in mouse tumor models or circulating monocytes from tumor bearers have phenotype which supports proangiogenic, metastatic functions thereby contributing to tumor progression.
Recent reports have suggested the existence of a novel subpopulation of monocytes/macrophages which are recruited preferentially to the tumors and carryout potent proangiogenic functions for tumor growth. Exploiting these cells, gene therapy approaches are being formulated in transgenic mice to target tumors. A collaborative project between Singapore Immunology Network (SIgN) and Hospital San Raffaele Scientific Institute (Milan,Italy) aimed at the molecular characterization of these novel monocyte subset (in human cancers and preclinical mouse models) and their potential use in gene therapy will be investigated. A 3 years postdoctoral position based in the Human Innate immunity lab in SIgN (Singapore) is immediately available (closing date February 2010) for this project. This project would involve active scientific exchange between the institutes in Singapore and Milan as well as provide strong future potentials for translational research.
We search for candidates with completed Ph.D., M.D., or equivalent degree and a good track record of international publications. Research experience in immunology (especially innate immunity), mice tumor models or with lentiviral or general cloning expertise will be advantageous. Fresh Ph.D. students who are passionate to carryout a career in cutting-edge science are also encouraged to apply. We offer core-funding for research work, broad range of technical facilities (imaging, transcriptomics/SIgN database, mouse mutant collection, monoclonal antibodies technologies, cell sorting and flow cytometry technologies, etc) and an international scientific environment.
Enquiries for this position may be directed to:
Dr. Subhra K. Biswas (e-mail: subhra_biswas@immunol.a-star.edu.sg) Principal Investigator, Human Innate Immunity lab,Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore.
Useful
links:
http://www.sign.a-star.edu.sg/scientists/sci_bio.php?content_id=2
http://www.a-star.edu.sg/tabid/773/default.aspx
Posted: December 16, 2009
Immunologist positions are immediately available to study innate and cellular immune responses to intracellular pathogens (e.g. Leishmania spp., adenovirus and hepatitis C virus). We seek highly motivated scientists who have recently received his/her M.D. or Ph.D. in immunology. Experience in immune cell activation assays, mouse handling and infectious pathogens is preferred but not required. Successful applicants are expected to write manuscripts, participate in laboratory meetings and journal clubs, and present at scientific meetings. Applications should include a brief description of research experience and career interests, curriculum vitae, and contact information of three professional references. Please contact Dr. Lynn Soong (lysoong@utmb.edu) or Dr. Jiaren Sun (jisun@utmb.edu), Dept. of Microbiology and Immunology, Univ. of Texas Medical Branch, Galveston, TX 77555-1019, USA. An Equal Opportunity/Affirmative Action Employer.
Posted: December 15, 2009
School of Medicine - Basic Medical Sciences
Post Doctoral
or Research Assistant Professor Position is available in Dr. Nilofer
Qureshi’s laboratory, Molecular and Cellular Immunology, Shock/Trauma
Research Center, University of Missouri, 2411 Holmes Street, Kansas City, MO
64108. Email qureshin@umkc.edu, Phone
no. 816 235-1056. FAX no. 816 235-6444.
This position is available immediately in the Molecular and Cellular
Immunology laboratory. Work will focus on understanding the role of the
proteasome in Septic Shock and designing new therapies for blocking
inflammation. The applicant must have an M.D./Ph.D., have a strong
experience in molecular/ cellular immunology, and in techniques such as
Western Blotting, SDS-PAGE, ELISA, Cytokine estimation and RT-PCR. This
position will be funded through the NIH grant entitled “Mechanisms involved
in the Septic Shock Syndrome”.
Posted: December 15, 2009
University of Michigan, Ann Arbor, MI
A T32 training grant fellowship opportunity is available in the Department of Pathology at the University of Michigan, working with Drs. Colin Duckett and Nick Lukacs on a project to examine mechanisms through which IAP (inhibitor of apoptosis) proteins,
a family of ubiquitin ligases, regulate the innate immune response to viral and asthmatic challenges.
The successful candidate will have a Ph.D. and strong training background in molecular and cellular immunology, strong work ethics and a demonstrated ability to work in a multidisciplinary team environment.
Per the requirements of the NIH Training Grant Policy, only US citizens or permanent residents can be considered.
Please e-mail: Cover letter, CV/Resume with references to: asavory@umich.edu.
Posted: December 15, 2009
Posted: December 14, 2009
A world-renowned laboratory studying the biology of graft versus host disease and graft versus leukemia in the Blood and Marrow Transplant Program at the University of Michigan is recruiting a highly motivated, experienced post-doctoral fellow to join a closely integrated team that is studying proteomic and cellular biomarkers for complications after hematopoietic stem cell transplantation. This position is funded by a 2 year NIH challenge grant project therefore priority will be given to U.S citizens/ permanents residents.
Requirements:
- Ph.D. and/or M.D. with substantial research experience in immunology and cell biology
- Demonstrated technical independence with flow cytometry (at least 6 colors with FlowJo software knowledge), T cells and dendritic cells culture and functional assays, and immunoassays (ELISPOT/ELISA), and/or confocal microscopy
- Meticulous at planning, executing, and organizing the results for large scale assays.
- S/he must also be capable of taking initiative, work independently and in a collaborative setting
- A good publication record in recognized peer-reviewed journals
- Excellent written and verbal (English) communication skills are required, as are excellent organizational skills and knowledge of proper scientific record keeping
Compensation: Salary according to the NIH scale + excellent benefits
Applicants should send an updated CV including publication list and two academic reference letters to:
Sophie Paczesny, M.D., Ph.D.
Assistant Professor Blood and Marrow Transplant Program University of Michigan Comprehensive Cancer Center
Email: sophiep@umich.edu
Posted: December 14, 2009
The laboratory of Dr. Edward Brown, of the Department of Biomedical Engineering, at the University of Rochester in Rochester, NY, has multiple opportunities for scientists with backgrounds in immunology, tumor biology, and/or biomedical imaging. Our objective is to understand the role of immune cells in shaping the tumor extracellular matrix and their subsequent influence on tumor metastasis. This project combines second harmonic generation imaging using multiphoton laser-scanning microscopy with immunohistochemistry and the manipulation of immune cell populations in vivo using genetic and pharmacological methods. The work will take place as part of an interdisciplinary team with backgrounds ranging from tumor pathophysiology to optics. The successful candidate will have a Ph.D. or M.D., an interest in immunological processes in cancer and/or biomedical imaging, as well as a demonstrated level of productivity. Molecular biology, histology and/or animal surgery experience are also desirable. Positions are available for highly qualified Postdoctoral Fellows and Research Assistant Professors, funded by a 5-year DoD Breast Cancer Research Program Era of Hope Scholar Research Award, as well as a 5-year NIH Director’s New Innovator Award. Applicants should send their curriculum vitae, list of publications and references, and a letter describing their interests to Dr. Edward Brown at edward_brown@urmc.rochester.edu.
Posted: December 11, 2009
Dr. Chengcheng (Alec) Zhang
Email: Alec.Zhang@UTSouthwestern.edu
Tel: 214-645-6320
Posted: December 11, 2009
We are seeking a postdoctoral fellow to investigate how estrogen controls the autoimmune T cell responses that are pathogenic in multiple sclerosis (MS), a complex neurodegenerative disease. Our current research aims to elucidate the mechanisms by which the hormone inhibits EAE.
We use a
variety of cutting-edge genetic, biochemical, immunological, and molecular
techniques in our research. OHSU has an excellent research environment
supported by outstanding research and training programs in the biological
sciences. Moreover, Portland, OR, is consistently rated one of the best
places to live in the USA.
The ideal candidate will be capable of conducting independent research,
contributing to the writing of manuscripts and grant applications, and
working well with scientific colleagues from diverse disciplines. The
candidate should have expertise in immunological methods and molecular
techniques and excellent English communication skills. Salary commensurate
with experience. To apply, please submit a cover letter explaining research
interests and expertise, accomplishments, and career goals, together with a
CV, 2-4 letters of recommendation, and 1-3 reprints to Dr. Offner at
offnerva@ohsu.edu. Correspondence:
Dr. Halina Offner, Portland VA Medical Center, Neuroimmunology Research
RD-31, 3710 SW US Veterans Hospital Rd., Portland, OR 97239.
Posted: December 10, 2009
Position #:09-49
Position: Postdoctoral Research Associate
Department: Bettelli Lab
Status: Full time
Responsibilities and Qualifications: A Postdoctoral Research Associate position is available in the department of Immunology to study the role of T helper 17 cells in different models of autoimmunity and cancer. The research project will focus primarily on the biology and functions of Th17 cells and cytokines associated with Th17 differentiation and inhibition in autoimmune diseases. Responsibilities include conceptualizing and executing experiments, data analysis, laboratory record keeping, oral and written presentation of experimental results. Highly motivated applicants with good organizational and analytical skills are encouraged to apply. A PhD in immunology or a related field is required. Experience/skills in immunology, cell biology, molecular biology (cell culture, flow cytometry, real-time PCR, Western blotting and ELISA) and animal models of autoimmunity and cancer are also required.
For application instructions please visit http://www.benaroyaresearch.org/employment and quote reference number 09-49 in your cover letter.
EEO - M/F
Posted: December 4, 2009
Detailed descriptions of these projects, and other ongoing research in the laboratories offering postdoctoral positions, are available at www.trudeauinstitute.org.
Trudeau
Institute, Inc. is a not-for-profit biomedical research institute with
state-of-the-art facilities and an international reputation for excellence.
Located in the heart of New York State's Adirondack Mountains overlooking
beautiful Saranac Lake, Trudeau offers competitive salaries and benefits,
including daycare and housing as well as a generous pension. Rated among the
top three "Best Places to Work" for scientists and postdoctoral fellows by
The Scientist. Trudeau fosters a highly collaborative research environment
focused on immunology and infectious disease.
Please send curriculum vitae, addresses of three references and a letter
describing your research interests to: Amy Richardson, Human Resource
Manager, Trudeau Institute, Inc., 154 Algonquin Avenue, Saranac Lake, NY
12983
Arichardson@trudeauinstitute.org.
Posted: December 1, 2009
An NIH funded postdoctoral research position is available immediately to study the molecular mechanisms of T-cell immune response and autoimmunity (JCI, 2009; MCB, 2009; Blood, 2008). Requirements include a Ph.D and/or M.D. in immunology or other cell biological field with an outstanding publication record. We are particularly looking for candidates with strong research background in cellular immunology and autoimmune diseases, such as type 1 diabetes and rheumatoid arthritis, using mice as animal models. Ph.D students graduated within two years are particularly encouraged to apply.
Please send your resume and names of three references of your current and previous mentors to:
Deyu Fang, Ph.D., Associate Professor, Department of Pathology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611-3008, E-mail: fangd@northwestern.edu
Northwestern University is an affirmative action/equal opportunity employer.
Posted: November 30, 2009
|
Institution/Organization: |
Washington University in St. Louis |
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Department Name: |
Pathology and Immunology |
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Job Title: |
Postdoctoral Fellow |
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Field of Study: |
immunology |
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Job Location: |
St. Louis |
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Job Description: |
A postdoctoral fellow position is available to study the cell-extrinsic mechanisms of development and lineage commitment in the immune system. The project will involve a combination of functional genomics, cell biology, and in vivo approaches to identify regulators of hematopoietic development, and to better understand the organization of the lymphoid and myeloid microenvironments. |
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Qualifications: |
Applicants must possess a doctoral degree (Ph.D. or M.D./Ph.D.) with experience in immunology or hematopoiesis. |
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Requirements: |
US citizens, permanent residents, candidates with independent funding, and applicants living in the US are strongly preferred. Candidates must not have more than 2 years of previous postdoctoral experience. |
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How to Apply |
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|
Materials needed to send: |
Please email curriculum vitae, a brief research interests statement, and contact information for 3 references. |
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Contact Name: |
Deepta Bhattacharya |
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Mailing Address: |
4940 Parkview Place |
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Email address: |
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Posted: November 30, 2009
A postdoctoral position is available immediately to study cell signaling in the immune system using autoimmunity, allergy and cancer models. For more information see Venuprasad K et al. Nat Immunol. 2008; 9(3):245-53, Venuprasad K et al. J Clin Invest. 2006.116(4):1117-26, Chang L et al. Cell. 2006; 124(3):601-13, Jeon MS et al. Immunity. 2004 21(2):167-77. The applicant should have completed a Ph.D. and/or M.D. in Immunology, Biochemistry, or Molecular Biology, The project involves gene cloning, siRNA, retroviral expression, cell signaling etc. The ideal candidate will have successful research experience in molecular biology, bio-chemistry and/or immunology. The successful candidate will be joining a very stimulating environment within the Karmanos Cancer Institute and the Dept. of Microbiology and Immunology at the Wayne State University. If interested, please send a CV and contact information of 2-3 references to Dr. Venuprasad K. Poojary at:
poojaryv@karmanos.org
Posted: November 24, 2009
We are seeking
a highly motivated postdoctoral research fellow candidate for research
projects related to the investigation of the latent HIV-1 reservoir.
Successful candidate will join Dr. Xu Yu's laboratory at the newly
established Ragon Institute at Massachusetts General Hospital/Harvard
Medical School. This institute fosters interdisciplinary, collaborative
research in HIV-1 pathogenesis and offers unique chances for scientific
career development for postdoctoral fellows.
Research Area
HIV-1 establishes a reservoir of latently infected cells that cannot be
treated by currently available antiretroviral drugs. We are interested in
understanding the mechanisms that maintain these latently infected cells,
and ultimately aim for developing novel treatment strategies that
specifically target this cell population. Our studies will take advantage of
unique HIV-1 patient cohorts established at MGH, such as individuals with
acute HIV-1 infection or with long-term spontaneous viral control. We will
closely collaborate with investigators from MIT to make novel chip-based
technologies available for these studies.
Requirements**
Ideal postdoctoral candidate will have strong backgrounds in HIV-1 virology,
biology, immunology and/or biochemistry with emphasis on molecular virology,
and/or cellular biology/immunology methods. Interested applicants can email
your CV with contact information for three references to Dr. Yu at
xyu@partners.org.
Xu Yu, M.D.
xyu@partners.org
Ragon Institute of MGH, MIT and Harvard
(formerly Partners AIDS Research Center)
Massachusetts General Hospital
149 13th Street, Rm6617
Charlestown, MA, 02129
Tel.: 617-724-4076
Fax: 617-726-5411
Posted: November 24, 2009
Two postdoctoral positions available immediately in the laboratory of Dr. Mark H. Siegelman, Departments of Pathology and Immunology, University of Texas Southwestern Medical Center at Dallas. Applicants should have a recent Ph.D. or M.D. with a strong research background in molecular and cellular immunology and immune regulation. Specific experience in murine models of immunity or human autoimmune disease is highly desirable, as is experience with multi-color flow cytometry, lymphocyte function analyses, and molecular biology.
1) Adhesion receptor function in T cell regulation and autoimmunity
Postdoctoral position studying the role of lymphocyte adhesion molecules in the regulation of inflammatory bowel disease and trafficking to inflammatory sites. Ongoing studies will use both cellular and molecular methods to characterize adhesion molecules as markers of regulatory T cells and their application to the control of human autoimmune disease and mouse models thereof (Blood 107: 619-627).
2) Adhesion receptor function in T cell regulation and transplantation
Postdoctoral position studying the role of lymphocyte adhesion molecules in the regulation of immune-mediated transplant rejection. Ongoing studies will use both cellular and molecular methods to characterize adhesion molecules as markers of regulatory T cells, their role in trafficking to the allograft, and their application to the control of organ transplant rejection (Blood 107: 619-627).
Qualified candidates should send a current Curriculum vitae describing their research background along with three (3) letters of reference to:
Mark Siegelman, M.D., Ph.D.
Department of Pathology MC9072
UT Southwestern Medical Center at Dallas
5323 Harry Hines Blvd.
Dallas, TX 75390-9072
mark.siegelman@utsouthwestern.edu
UT Southwestern is an Equal Opportunity, Affirmative Action Employer.
Posted: November 20, 2009
A postdoctoral position is available immediately for a highly motivated individual in the laboratory of Dr. Kathleen Pratt at the Puget Sound Blood Center in Seattle, WA. Opportunity to work with an interdisciplinary team investigating the development of neutralizing antibodies in hemophilia A patients following therapeutic infusions of factor VIII protein.
The project involves isolation and characterization of T cells from hemophilia A blood samples, including serial samples obtained prospectively. Antigen-specific T-cell clones and polyclonal lines are generated using MHC Class II tetramers and characterized using RT-PCR, ELISAs, proliferation assays, ELiSpot, etc. Immunodominant T-cell epitopes will be identified and modified in a project aimed at designing less immunogenic versions of factor VIII targeted to specific populations. Special emphasis is placed on investigating immunologic mechanisms responsible for the greater immunogenicity of factor VIII in hemophilia A patients with black African ancestry.
Requirements: Highly motivated Ph.D., M.D., or M.D./Ph.D. with a strong background in immunology and T-cell biology. Experience with flow cytometry and RT-PCR. The successful candidate will have excellent communication skills and will enjoy working with an interdisciplinary team including immunologists, protein chemists and structural biologists.
The laboratory is part of the Puget Sound Blood Center, in Seattle, WA. The research environment includes state of the art instrumentation and access to clinical material. Interested candidates should read Ettinger RA et al., Blood 114:1423-28, 2009, and James EA et al., J. Thromb. Haemost. 5:2399-2407, 2007.
Please e-mail curriculum vitae, reprints, addresses and telephone numbers of three references to: Kathleen P. Pratt, Ph.D., kathleenp@psbcresearch.org.
Posted: November 20, 2009
An NIH funded postdoctoral position is available in the Center for Immunology and Microbial Disease at Albany Medical College, Albany, New York, in the laboratory of Dr. Edmund Gosselin, to study Fc receptor-enhanced protection against infection with the intracellular mucosal pathogen Francisella tularensis and the extracellular mucosal pathogen Streptococcus pneumoniae. Individuals should have a Ph.D. in Immunology, Microbiology, or a related field. Experience working with animal models is preferred, but not required.
Interested individuals should send a copy of their CV, the names of three references, and a letter describing their research interests and goals to Dr. Edmund Gosselin at the address below.
Edmund J. Gosselin, Ph.D.
Associate Professor
Center for Immunology & Microbial Disease, MC-151 Albany Medical College Albany, NY 12208
E-mail: gossele@mail.amc.edu
Phone: 518-262-5562
FAX: 518-262-6161
Posted: November 18, 2009
A
postdoctoral position is available immediately to investigate the mechanisms
of host resistance against an intracellular protozoan parasite, Toxoplasma
gondii, using murine models. The projects include studies of interactions
between innate immune cells and T cells in host defense and vaccine
development. Individuals with a Ph.D. and a strong background in immunology
and cellular/molecular biology are desirable.
Send curriculum vitae, a short description of research experience and
interest, and names and addresses of three references to: Yasuhiro
Suzuki, Ph.D., Professor, Department of Microbiology, Immunology and
Molecular Genetics, University of Kentucky College of Medicine, 800 Rose
Street, Lexington, KY 40536. E-mail:
yasu.suzuki@uky.edu.
Posted: November 18, 2009
We have an opening for a full time postdoctoral fellow in Immunology of Food Allergy in the Dreskin Laboratory at University of Colorado Denver, Anschutz Medical Campus.
Stephen
C. Dreskin - PI:
stephen.dreskin@ucdenver.edu
http://www.uchsc.edu/sm/deptmed/clinimm/faculty/dreskin.htm
Allergy & Clinical Immunology
B164, R2
12700 E. 19th Ave.
Aurora, CO 80045
Phone Number: 303-724-7190
Fax Number: 303-724-7190
Requirements:
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| Job Description: |
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| Salary: NIH Postdoctoral pay-scale with excellent benefit package. |
| Application: |
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1) Cover letter including a brief
description of career interests |
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Position available immediately. Review of
applications will continue until position is filled. The University of Colorado Denver is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees prior to their employment. The University of Colorado is committed to diversity and equality in education and employment. Candidates must apply at www.jobsatcu.com posting# 808335 with a resume, cover letter, and a list of at least 3 references including contact information. Contact Sara Higgins, Division Administrator, at Sara.Higgins@ucdenver.edu with questions. Posted: November 17, 2009 |
Qualifications: Ph.D. or M.D. is required.
Contact: Interested candidates send a cover letter, brief statement of research goals, an updated curriculum vitae including list of publications, and the names (include contact info) of three references to:
Rivkah Gonsky
Inflammatory Bowel Disease Center
Davis 4063
8700 Beverly Blvd
Los Angeles, CA 90048
310-423-7624
gonsky@cshs.org
Posted: November 16, 2009
The ideal candidate will be capable of establishing independent research projects, possess excellent English communication skills, work well with scientific colleagues from diverse backgrounds, feature a strong publication record in microbiology and/or immunology, have experience with microbial RNA expression techniques (microarrays and/or deep sequencing), and be a U.S. citizen with NIH or equivalent funding. Interested candidates should submit a c.v., cover letter outlining research interests, three references, and up to five article reprints. Applications should be submitted by email to the PI at: mhhsieh@stanford.edu.
Posted: November 16, 2009
A postdoctoral position is available in the Department of Immunology and Microbial Science at The Scripps Research Institute, La Jolla, to study the functions and molecular mechanisms of microRNA control in lymphocyte development, immune responses, immune tolerance, autoimmune diseases, and lymphoma. For more information, see Cell (2007) 131:146-59, Nature Immunology (2008) 9:405-14, Cell (2009) 136:26-36.
Requirements: Highly motivated Ph.D., M.D., or M.D./Ph.D. with a solid background in immunology.
Working experience in the following areas is desired: the mouse immune system; immune tolerance; mouse models of autoimmune diseases or lymphoma; lentiviral or retroviral systems for gene expression; bone marrow reconstitution.
Candidates should be fluent in English, and can be available for interview.
Please e-mail application including cover letter indicating current and future research interests and expected availability date, CV, selected reprints of publications, names and contact information of three references to:
A bioinformatician position at the postdoctoral level is available in the Department of Immunology and Microbial Science at The Scripps Research Institute, La Jolla, to study the functions and molecular mechanisms of gene regulation by microRNAs and other small non-coding RNAs in the immune system, and in lymphoma and autoimmune diseases. For more information, see Cell (2007) 131:146-59, Nature Immunology (2008) 9:405-14, Cell (2009) 136:26-36.
Requirements: Highly motivated Ph.D. with a solid background in biology, bioinformatics, and computer programming.
Working
experience in the following areas is highly
desired: 1. microRNAs and other small non-coding RNAs; 2. Next generation
sequencing; 3. RNA-binding proteins; 4. Bioinformatics; 5. Biostatistics; 6.
Proteomics
Candidates should be fluent in English, and can be available for interview.
Please e-mail application including cover letter indicating current and future research interests and expected availability date, CV, selected reprints of publications, names and contact information of three references to:
Changchun Xiao
Assistant Professor, Department of Immunology and Microbial Science, IMM-202
The Scripps Research Institute, 10550 N. Torrey Pines Road La Jolla, CA
92037
Email: cxiao@scripps.edu *
http://www.scripps.edu/ims/xiao
Postdoctoral position available for a Ph.D. or M.D. with experience in cellular immunology. Our studies focus on the mechanisms underlying autoimmune disease (such as type 1 diabetes and rheumatoid arthritis) and the role of inflammation in type 2 diabetes.
Please e-mail curriculum vitae, reprints, addresses and telephone numbers of three references to: Dr. Daniel L. Kaufman at dkaufman@mednet.ucla.edu.
Daniel L. Kaufman, Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA 90095-1735.
Posted: November 6, 2009
The laboratory is focusing on three related areas. The first is concerned with the identification of new autoantigens, the autoantibodies with which these autoantigens react and the value of autoantibodies in predicting the development of autoimmune diseases. The long-term goal is to define the human “autoantigenome” --- that is the identification and characterization of the major autoantigens in the most common human autoimmune diseases ---by high throughput procedures and extensive screening of the proteome. (Notkins, A.L.: Scientific American, 296, 72-9, 2007).
The second area concerns the properties and function of IA-2 and IA-2 β which are major autoantigens in type 1 diabetes and transmembrane proteins of secretory vesicles (dense core and synaptic). These proteins are present in most of the neuroendocrine cells in the body. Knockout, knockdown and overexpression experiments have shown that these proteins affect the secretion of hormones and neurotransmitters. Current studies are concerned with the effect of IA-2 and IA-2 beta on secretion and how this, in turn, alters behavior, learning, circadian rhythm and the immune system. (Harashima, S, etal.: Proc. Natl. Acad. Sci. USA, 102, 8704-8709, 2005; Nishimura, T.: Neuroscience, 159, 427-437, 2009; Kim, S. M.: The FASEB Journal, 23, 3226-3232, 2009).
The third area involves polyreactive antibodies. Hybridoma technology has shown that many antibody molecules are polyreactive — that is, they can bind to a variety of different and structurally unrelated self and non-self foreign antigens. These antibodies generally have low binding affinity and are encoded by germ-line or near germ-line sequences. Further studies revealed that much of the natural antibody repertoire is made up of polyreactive antibody. The function of the natural antibody repertoire has remained an enigma. Current studies are focusing on the role of polyreactive antibodies in: defense against foreign organisms (i.e., bacteria/viruses); the clearance of damaged proteins and cells; and the possible role of these antibodies in the induction and/or maintenance of immunological tolerance. The cells that make and regulate polyreactive antibodies also are under investigation. (Notkins, A.L.:Trends in Immunol, 25,174-179, 2004; Zhou,Z-H, etal: Cell Host & Microbe, 1, 51-61, 2007).
Applicants must have a Ph.D., M.D. or equivalent with experience in cellular immunology and/or neuroendocrinology. Send your CV with cover letter to:
Abner Louis Notkins, M.D., Chief, Experimental Medicine Section, NIDCR, NIH; Bldg. 30, Rm. 106, 30 Convent Drive, Bethesda, Maryland 20892, USA; E-mail: anotkins@mail.nih.gov: Tel: 301-496-4535.
Posted: November 6, 2009
One of our research focuses (position 1) is to study the defects of HLA and antigen processing and presentation machinery components in tumor cells. Suitable candidate must have a Ph.D. degree and a strong research background in Immunology and Molecular Biology.
The other one of our research focuses (position 2) is to study the anti-tumor mechanisms of action mediated by chondroitin sulphate proteoglycan 4 (CSPG4) - specific monoclonal antibodies. Suitable candidate must have a Ph.D. degree and a strong research background in Cell biology and Signal transduction.
Candidates for both positions should be highly self-motivated and able to communicate well verbally and work independently.
To Apply: Send a letter of intent describing research accomplishments and plans, CV, and the names and contact information of 2-3 references to:
Soldano Ferrone, M.D., Ph.D.
University of Pittsburgh Cancer Institute
5117 Centre Avenue Suite 2.27
Pittsburgh, PA 15213
Phone: (412) 623-5040
Fax: (412) 623-4840
E-mail: ferrones@upmc.edu
Posted: November 6, 2009
Streptococcus pneumoniae is a major cause of respiratory infections in humans, such as pneumonia and otitis media and invasive infections, as meningitis and sepsis. Our proposal is to apply epitope dampening to protective pneumococcal antigens by site-directed mutagenesis to deviate the immune response to potentially more conserved secondary epitopes. These new molecules would be evaluated as to the induction of a broader immune response and protection.
A FAPESP fellowship will be available at the Center of Biotechnology, Instituto Butantan to work on this project. The candidate should have experience with bioinformatic tools and molecular biology, as well as working experience in microbiology and immunology. Instituto Butantan is a Biomedical Research, Development and Production Institute in São Paulo, Brazil -- www.butantan.gov.br.
Those interested should send their C.V. to Luciana C. Leite, Centro de Biotecnologia, Instituto Butantan, lccleite@butantan.gov.br until 15/11/2009.
Luciana
C. C. Leite, Ph.D.
Centro de Biotecnologia
Instituto Butantan
Av. Vital Brasil 1500
05503-900 São Paulo, SP, Brasil
Tel/Fax: 55-11-3726-9150
Posted: November 3, 2009
Applications are invited from M.D. and/or Ph.D. candidates interested in studying mechanisms of autoimmunity and immune tolerance, as it relates to the development and progression of autoimmune diseases such as SLE, rheumatoid arthritis and scleroderma. Current projects include dendritic cell migration and activation in immune tolerance and inflammation with a current focus on skin dendritic cells in lupus dermatitis; role of tissue gamma delta T cells, and NKT cells and autoreactive T cells in autoimmune inflammation; mechanisms of gender bias in autoimmunity, particularly the role of sex chromosomes; and mechanisms and biomarkers of tissue fibrosis in autoimmune diseases. Positions are funded by T32 and other grants from the NIH. US citizen / permanent resident and minority applicants are particularly encouraged to apply.
Please send your CV and a list of three references to Ram Raj Singh, M.D., rrsingh@mednet.ucla.edu.
Posted: November 3, 2009
Available immediately to study mechanisms governing the differentiation and function of CD4 T lymphocytes and the roles that these cells play in control of autoimmunity and maintenance of immune homeostasis at environmental interfaces. The applicant must have recently completed a PhD or equivalent in Immunology, Biochemistry, Molecular Biology, Genetics, or a related field. The ideal candidate will have expertise in flow cytometry, tissue culture, molecular biology, mouse handling, and an interest in cytokine signaling and epigenetic mechanisms of gene regulation. The successful candidate will be joining a young, dynamic environment within the Center for Cellular and Molecular Immunology at the University of Missouri in Columbia.
Interested applicants should send a cover letter, CV, summary of previous research experience, and three letters of references to Dr. Susan McKarns @ mckarnss@health.missouri.edu.
Posted: November 3, 2009
A Postdoctoral position is available for a highly motivated individual in the laboratory of Dr. Esteban Celis at Moffitt Cancer Center. The research is focused on the development of T cell epitope vaccines for cancer. Research is being conducted both in human clinical studies and animal cancer model systems. Areas of investigations include studies of the effects of tumor microenvironment on the effectiveness of infiltrating T cells and investigation of signal transduction and transcriptional regulation in these cells.
The successful candidate should have a strong background in immunology and/or molecular biology, and interests in tumor immunology and T cell biology. Detailed knowledge and sufficient experience with flow cytometry, as well as experience working with mice, are absolute requirements. The successful candidate will have excellent communication skills and command of the English language.
The laboratory is located in the NCI designated Moffitt Cancer Center, situated on the campus of the University of South Florida in Tampa. The research environment includes state of the art modern core facilities and pathogen-free modern animal facilities, access to clinical material, etc.
The funding source for this position dictates that only US citizens or Permanent Residents, who have recently graduated with a Ph.D. degree in Immunology or related field, are eligible for consideration.
Please visit www.moffitt.org/careers to apply online to Req 5194 and send CV, cover letter and three references to Dr. Esteban Celis at esteban.celis@moffitt.org.
Posted: October 30, 2009
Postdoctoral Position: Immunology of Mycobacterium tuberculosis infection
A Postdoctoral Researcher position is available within the laboratory of Dr. Joanne Turner at The Ohio State University Medical Center, Center for Microbial Interface Biology (CMIB). The Ohio State University represents an emerging leader in host-pathogen studies. The research project will be focused on defining immune correlates of susceptibility to M. tuberculosis infection, using the murine model of infection. Opportunities to initiate translational studies are also available. Candidates must possess a PhD or MD in Microbiology, Immunology, or related field. A background in immunology and/or animal models is desired. Individuals with a strong interest in host-pathogen interactions are encouraged to apply. Experience in biosafety level 3 work practices are desirable but not required (training will be provided). More information concerning the CMIB and Dr. Turner’s laboratory can be obtained at http://cmib.osu.edu. Applicants should submit a letter of interest, C.V., and the names of three potential references electronically to joanne.turner@osumc.edu (preferred) or by mail to: Dr. Joanne Turner, Center for Microbial Interface Biology, 460 W. 12th Avenue, 1010 Biomedical Research Tower, Columbus, OH 43210. Applications will be accepted until the position is filled. To build a diverse workforce Ohio State University encourages applications from individuals with disabilities, minorities, veterans, and women. Flexible work options are available. EEO/AA employer.
Posted: October 28, 2009
Postdoctoral
fellow position available
Immunity to rickettsial infection
A postdoctoral fellow position is immediately available to study the cellular immune response to rickettsial infection. We seek a highly motivated and enthusiastic scientist who wishes to vigorously pursue in research on intracellular bacteria. The candidate should have PhD, MD, or equivalent degree within the last 5 years, with a demonstrable publication record. Candidates are expected to have experience in molecular and cellular immunology including Toll like receptor signaling pathways. Experience in working with infectious pathogens and animals is preferred.
Salary is commensurate with experience.
Interested candidates should send a CV, outline of research interests and names of four references, preferably by email, to:
David H.
Walker, M.D.
UTMB Department of Pathology
301 University Boulevard
Galveston, Texas 77555-0609
dwalker@utmb.edu
Posted: October 27, 2009
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Post-Doctoral -Associate Research Scientist - Immunobiology & Cancer (CWebb)
Postdoctoral position available immediately to pursue collaborative studies on cell development and lineage decisions. Additional information about the Immunobiology and Cancer Program can be found at the Oklahoma Medical Research Foundation web site: http://www.omrf.org/OMRF/Research/14/Welcome.asp
OMRF is an independent, not-for-profit, biomedical research institute adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City. OMRF investigators enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs.
Minimum Qualifications: Ph.D., M.D., or Ph.D./M.D.
Preferred Qualifications: Successful candidates for this training position should have prior tissue culture experience and a strong background in molecular biology, developmental biology, and/or immunology, as well as aspirations for an independent scientific career. Preference will be given to candidates with documented success in research, such as recent first author publications.
Interested persons should send a CV, statement of research interests and names of three references to: Carol F. Webb, Ph.D., E-mail: Carol-Webb@omrf.org, FAX: (405) 271-7128.
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Post-doctoral - Associate Research Scientist - Arthritis and Immunology - (DFarris) - Oklahoma Medical Research Foundation
We are seeking an Associate Research Scientist to investigate the intersection of inflammation and microthrombus formation in thrombotic thrombocytopenic purpura (TTP). Both human and mouse studies are employed to understand inflammatory triggers of TTP. The applicant will also contribute to other studies of immunity/autoimmunity in the laboratory.
Oklahoma Medical Research Foundation (OMRF) is an independent, not-for-profit, biomedical research institute adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City. OMRF investigators enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs.Minimum Qualifications: Ph.D., M.D., or M.D./Ph.D., or DVM/Ph.D. First-author publication(s) in internationally recognized journals in the fields of immunology, inflammation, hematology and/or cardiovascular biology. Motivation and ability to keep abreast of the current literature as well as his/her own experiments. Willingness to interact with other members of the laboratory in a way that raises the scientific excellence of the whole group. Excellent scientific writing and oral presentation skills.
Preferred Qualifications: Experience in microthrombus detection/quantification and/or expertise in hematology will be strongly preferred.
Interested individuals should send a CV, statement of research interests/career goals, and the names and contact information of three references to Darise Farris at darise-farris@omrf.org or by mail to: A. Darise Farris, Ph.D., Asst Member, OMRF, ms 24, 825 NE 13th Street, Oklahoma City, OK 73104 USA.
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Post-Doctoral - Associate Research Scientist - Arthritis & Immunology (JHarley):
We are currently accepting applications for positions at the level of post doctoral fellow to join our research team. We are funded for projects in genetics of Systemic Lupus Erythematosus (SLE). We are hoping to develop the molecular mechanisms for the genetic effects discovered and would be interested in a cell or molecular biologist or virologist to work in this area. We also have ongoing projects focused on gene discovery including family studies (both genome-wide linkage and association), population-based case-control association (genome-wide as well as candidate gene) studies using high density SNP Arrays (Affymetrix and Illumina), and admixture mapping. We are particularly interested in establishing the role of Epstein-Barr virus in SLE pathogenesis. We offer an excellent team-oriented research environment and opportunities for career advancement. Our team has a high throughput molecular laboratory and a strong array of analytical computing resources.
Oklahoma Medical Research Foundation (OMRF) is an independent, not-for-profit, biomedical research institute adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City. OMRF investigators enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs.
Minimum Qualifications: Ph.D., M.D., or Ph.D./M.D.
Preferred Qualifications: A candidate should have a doctoral degree in immunology, biochemistry, genetics, cell biology, or virology, but those with degrees in epidemiology, biostatistics, bioinformatics, statistics, or computer science will also be considered. The successful applicant is expected to have a strong interest in the mechanisms of genes in complex traits. Experience with genomic manipulation, expression studies, and functional characterization of genes will be given preference. Knowledge of statistical genetic methods for gene-mapping for complex traits, and computer programming skills (e.g. familiarity with UNIX-like OS, and at least one programming language) are preferred, but bench experience in the laboratory is the most important.
Please send a curriculum vitae and summary of research interests to: John B. Harley, M.D., Ph.D., Member, Arthritis and Immunology Research Program, Oklahoma Medical Research Foundation. Ph: 405-271-7765; Fax: 405-271-4110; Email: Jennifer-Kelly@omrf.org.
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Post-Doctoral - Associate Research Scientist - Clinical Immunology (JJames)
Seeking highly motivated, self-starter with ability to work with little direct supervision. Join my lab and explore how the autoimmune response in SLE and related disorders starts and progresses over time. Understand the genetics of a complex autoimmune disease, explore the role of viruses in the initiation of lupus in predisposed individuals, and elucidate the role of autoantibodies in disease pathogenesis in American Indians.
Oklahoma Medical Research Foundation (OMRF) is an independent, not-for-profit, biomedical research institute adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City. OMRF investigators enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs.
Minimum Qualifications: Ph.D., M.D., or Ph.D./M.D. Previous exposure to basic immunology and molecular biology techniques required. Good written skills necessary. Ability to communicate and write summaries of results required.
Preferred Qualifications: Ideally would have at least two publications with at least one first author, peer-reviewed, English manuscript.
Send CV and list of three references to: Judith James, M.D., Ph.D., E-mail: Postdoc-Recruiting@omrf.org.
Posted: October 27, 2009
A postdoctoral position at Dartmouth Medical School is immediately available to test the use of novel nanomaterials to transform the phenotype of ovarian cancer microenvironmental leukocytes in vivo. Current work in the laboratory focuses on modifying the transcriptional profile of different leukocyte subsets through RNA delivery as a novel intervention against ovarian cancer.
A postdoctoral
position in our lab is immediately available. The applicant should be a
graduating Ph.D. student or postdoctoral fellow with a strong background
immunobiology. Familiarity with molecular biology is highly desirable.
Applicants please send curriculum vitae with a description of research
interests and names of three references with email addresses to:
Jose R Conejo-Garcia, M.D., Ph.D.
Assistant Professor of Microbiology and Immunology Assistant Professor of
Medicine Dartmouth Medical School Borwell Building-Room 640W, HB 7556
1 Medical Center Dr.
Lebanon NH 03766
e-mail:
Jose.R.Conejo-Garcia@Dartmouth.edu
Phone: (603) 650-6822
Fax: 603-650-6223
Posted: October 27, 2009
NK cells and virus immunity
University of Virginia
A post-doctoral research position is available immediately in the lab of Michael Brown, Ph.D. at the University of Virginia. Ongoing research in the lab is focused on the role of NK cells in host resistance to viral infection and their ability to influence other immune cells, antiviral defenses and immune pathology. Highly motivated individuals with a Ph.D. and demonstrated expertise in molecular genetics, immunology or virology are encouraged to apply.
Interested candidates should submit their curriculum vitae and contact information for three references to Dr. Michael Brown, Carter Immunology Center, University of Virginia, Box 801386, Charlottesville, VA 22908. (E-mail: mgb4n@virginia.edu)
Position
opened until filled.
The University of Virginia is an Equal Opportunity/Affirmative Action
Employer.
Posted: October 23, 2009
We are looking for a highly motivated and talented individual. The candidate must hold a doctoral degree in immunology, cell and molecular biology, biochemistry or a related field; recent graduates are encouraged to apply. Strong laboratory experience in molecular and immunological techniques and in working with mice is required. Suitable candidates should be able to communicate well verbally and work independently. Salary will be commensurate with experience.
Please send a letter of application that summarizes your research interests and career goals, CV, and names and contact information for three references to:
Dr. Wendy Watford
E-mail: watfordw@uga.edu
University of Georgia
Department of Infectious Diseases
501 D.W. Brooks Dr.
Athens, GA 30602
Phone: (706) 542-4585
Fax: (706) 542-5771
Applications received by November 30 will be given full consideration. The University of Georgia is an Equal Opportunity/Affirmative Action employer.
Posted: October 21, 2009
A postdoctoral fellowship position is available to train in the field of solid organ transplant immunology. The successful candidate will work with an exciting team of scientists at the Northwestern University Comprehensive Transplant Center. The main focus of the laboratory is to develop immune monitoring assays for monitoring subjects enrolled in ongoing clinical trails of transplantation tolerance at our center which is one of the largest transplant centers in the country. The candidate will work under the supervision of Dr. M. Javeed Ansari to do studies specifically related to Th17 immunity and to elucidate the mechanisms of allograft rejection and tolerance. Strong background in immunology is required. Professional development of the trainees is facilitated. The center has a number of renowned investigators doing transplantation immunobilogy research including Drs. Joshua Miller and Stephen D. Miller who will serve as co-mentors. There is ample opportunity for interaction and collaboration with other scientists within the center and the Microbiology-Immunology Department at Northwestern University Feinberg School of Medicine.
For more information, refer to: Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10734-9; J Exp Med. 2008 Dec 22;205(13):3133-44
Please send CV and reference information to:
M. Javeed
Ansari, M.D.
Assistant Professor of Medicine
Division of Nephrology and Organ Transplantation/Department of Medicine
Feinberg School of Medicine
Northwestern University
Tarry Bldg, Suite 11-723
300 E. Superior, Chicago, IL 60611
Tel: 312-503-2677
Fax: 312-503-3366
E-mail: jansari@northwestern.edu
Posted: October 21, 2009
John W Schrader
Email: john@brc.ubc.ca
The Biomedical Research Centre
2222 Health Sciences Mall, UBC
Vancouver, BC
V6T 1Z3
Canada
Novel strategies for the generation of monoclonal antibodies and studies of
human B lymphocytes
The ideal candidate will have gained a Ph.D within the last 2 years, with expertise in molecular biology, tissue culture and flow cytometry and protein purification and be interested in working in an innovative, multidisciplinary team . However, all qualified candidates are encouraged to apply.
The Biomedical Research Centre (BRC) (www.brc.ubc.ca/) at the University of British Columbia. is an interdisciplinary research centre which gathers together in open-design laboratories, nine UBC faculty members in the Faculties of Medicine and of Science, variously affiliated with the Departments of Medicine, Medical Genetics, Pathology and Laboratory Medicine, Cellular & Physiological Sciences, Chemistry, Zoology, and Microbiology and Immunology. The students, postdoctoral fellows and technicians supervised by these faculty members work alongside each other, sharing their knowledge and techniques. The BRC has state-of -the art core facilities including those for cell-sorting, proteomics, tissue culture and mouse genetics .
Applications received by October 30th, 2009 will be given priority but the position will remain open until filled. To apply, please forward a concise statement of research interests and career goals, a curriculum vitae, and the name, e-mail address and phone number of three referees to John Schrader (john@brc.ubc.ca).
Posted: October 16, 2009
Postdoctoral Fellow - Molecular Biology & Physiology
The
collegial atmosphere at City of
We are seeking an experienced Research Fellow to join the laboratory within the Department of Gene Regulation and Drug led by Barry Marc Forman, M.D., Ph.D. The focus of the lab is to utilize orphan nuclear receptors to identify novel signaling pathways; to elucidate their molecular mechanism of action and to study their physiological effects.
Over the past few years, we have discovered several new signaling molecules that regulate critical molecular and cellular events including fat cell formation, glucose homeostasis and cholesterol metabolism and drug and sterol clearance. Among these recent discoveries was the identification of the first new steroid hormone to be discovered in 30 years. Thus, orphan receptors define exciting new areas of research, which have significant implications for both basic research, metabolic disease, diabetes, cancer and the design of new drug therapies.
Molecular biology, animal models and other techniques will be used including interactions with chemists and a variety of core facilities (high-throughput screening, mass-spec, etc.). Suitable candidates will have a Ph.D. with experience and potential in modern molecular biology and physiology.
To Apply: Please submit a statement of research interests and/or experience, a current curriculum vitae, and names and addresses of three references to Dr. Forman c/o Eileen Sepulveda: esepulveda@coh.org EOE/AA
For more information, visit our lab's web site at www.cityofhope.org/bforman/
At
City of
KW:
Posted: October 15, 2009
Post Doctoral Fellowships
Innate and Adaptive Immunity within the Central Nervous System
Available Immediately at the Cleveland Clinic, Departments of Neurosciences and Immunology, Cleveland, OH, USA
Expertise in cellular immunology, viral pathogenesis or neurobiology required. Experience with experimental murine models preferred. Ph.D. required in the areas of Immunology, Virology, or Neuroscience related fields.
Research Areas: Innate antiviral effector mechanisms in glia; Mechanisms of T cell maintenance and effector functions within the CNS; and Regulatory mechanisms controlling viral persistence and immune mediated pathology. Candidates can choose between various interrelated projects focusing on regulation of innate and adaptive immune responses to acute and persistent viral infection of the central nervous system. Neurotropic coronavirus infection is used as an experimental model of acute encephalitis resolving into a persistent infection associated with myelin loss. Both CD4 and CD8 T cell functions are involved in the demyelinating process, reflecting hallmarks of multiple sclerosis. Projects are carried out within a highly interactive, multi-disciplinary group within adjacent laboratories directed by Drs. Bergmann, Stohlman (Neurosciences) and Min (Immunology). Dr. Bergmann’s projects investigate differential innate responses of glia cell types to viral infection with an emphasis on crosstalk between microglia/monocytes and oligodendrocytes. Dr. Min’s project explores the ability of persisting virus, characterized by low RNA levels, to trigger ongoing CD4 and CD8 T cell responses. The role of glia and dendritic cells in maintaining T cells within the CNS during the persistent phase associated with ongoing demyelination comprises a major component. Dr. Stohlman’s project focuses on mechanisms dampening inflammation and antiviral function, allowing survival of the host at the cost of viral persistence and demyelination. Emphasis is placed on the role of IL-10 and T regulatory cells. Use of transgenic, knockout and conditional knockout mice, flow cytometry and cell sorting of CNS derived cells, as well as confocal and immunohistochemical analysis are integral components of all projects. (http://www.lerner.ccf.org/neurosci/bergmann/, http://www.lerner.ccf.org/neurosci/stohlmann/, http://www.lerner.ccf.org/immuno/min/)
Selected Publications:
Bergmann, CC, TE Lane, SA Stohlman. (2006) Coronavirus infection of the CNS: Host-virus standoff. Nature Reviews Microbiol. 4:121-132.
Phares TW, C Ramakrishna, GI Parra, A Epstein, L Chen, RAtkinson, SA Stohlman, CC Bergmann. (2009) Target Dependent B7-H1 Regulation Contributes to Clearance of CNS Infection and Dampens Morbidity. J. Immunol. 182(9):5430-8.
Ireland DC, SA Stohlman, DR Hinton, P Kapil, R Silverman, R Atkinson, CC Bergmann. (2009) RNase L mediated protection from virus induced demyelination. PloS Path. Oct;5(10):e1000602. Epub 2009 Oct 2.
Do, J. and B. Min. (2009). IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and gd T cells in vivo. Blood 113: 6361-6371.
Do, J. and B. Min. (2009). Differential requirements of MHC and of DCs for endogenous proliferation of different T cell subsets in vivo. Proc. Natl. Acad. Sci. USA In Press.
Please email CV and contact of 3 referees to: Dr. Conni Bergmann, bergmac@ccf.org
Posted: October 15, 2009
Several NIH-funded Postdoctoral positions are available immediately for studies in Mucosal Immunology at the Albany Medical College. The projects focus on determining the mechanisms responsible for pathogenesis and protection against viral and bacterial infections in the pulmonary tract, including pathways leading to synergistic H1N1 influenza virus and MRSA infections. Applicants should have a Ph.D. in Immunology, Microbiology, Cell Biology, or a related field, and have no more than five years of relevant postdoctoral experience. The position includes a competitive salary and full benefits with ample opportunity for research collaborations within the Center as well as neighboring institutions. Albany Medical College is located in a mid-sized city within the upstate New York Capital Region and has easy access to Boston, New York City, and the Adirondack Mountains. To apply, please send a curriculum vitae, a brief letter outlining research experience, and the names and addresses of three references to:
Dennis W. Metzger, Ph.D.
Theobald Smith Alumni Chair, Professor and Director
Center for Immunology and Microbial Disease
Albany Medical College, MC-151
47 New Scotland Avenue
Albany, New York 12208
http://www.amc.edu/Academic/Research/imd.htm
Posted: October 14, 2009
We have a position for an outstanding postdoctoral fellow with strong expertise in cellular and molecular immunology and an excellent publication record in internationally renowned journals. The successful candidate will use our unique mouse models along with primary or tissue culture cell based assays to analyze the functions and molecular mechanisms of action of novel genes that we identified in forward genetic screens in mice, or in cell-based RNAi-screens, and hypothesize to be important for immunocyte development or function. In particular, the candidate will investigate the functions of selected genes in swine-flu or LCMV infections and pathology.
For more details, see Science 316, 886-889 (2007), Molecular Cell 33, 43-52 (2009) and www.scripps.edu/ims/sauer.
Requirements: Substantial expertise in relevant techniques, including analyses of responses to virus infections (LCMV, Influenza etc.) in mouse models, analyses of immune system development or peripheral lymphocyte function in mouse models, RNAi studies in mice or tissue culture cells, retro- and lentiviral transduction techniques, biochemistry, in vivo and in vitro assays for CD4 effector/memory T cell, TH1/2/17, Treg or cytotoxic CD8 T cell function. Strong expertise in analyzing cytokine, effector and memory responses to chronic or acute viral infections will be a particular advantage. In addition to outstanding scientific credentials, very strong work ethics and a proven ability to work independently with minimal supervision, the successful candidate will have a pleasant, friendly personality and enjoy working in a fast-paced, multidisciplinary but focused academic team environment. S/he will have an excellent, fluent oral and written command of the English language and enjoy to actively participate in scientific discussions in a challenging and stimulating, leading research environment.
If you are interested in joining us, please submit your CV, a brief outline of your research interests and a list of at least three references to ksauer@scripps.edu.
Karsten Sauer, Ph.D.
Department of Immunology and Microbial Science
The Scripps Research Institute (TSRI)
Room R219, Mail Stop IMM-24
10550 North Torrey Pines Road
La Jolla, CA 92037, USA
Email: ksauer@scripps.edu
Webpage:
www.scripps.edu/ims/sauer
Posted: October 12, 2009
Postdoctoral positions are available in the laboratory of Dr. Robert A. Colbert, Chief, Pediatric Translational Research Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), at the NIH, to study the molecular pathogenesis of spondyloarthritis in animal models and humans. We are interested in the functional significance of susceptibility genes including HLA-B27, ERAP1/ARTS1, IL23R, and others, and their role in determining phenotype. Previous work has uncovered a novel mechanism involving HLA-B27 misfolding and ER stress as a possible trigger for inflammation through unfolded protein response-induced activation of the IL-23/IL17 axis in transgenic rats. Projects are being developed in several areas including: 1) the role of additional susceptibility genes in controlling phenotype including new bone formation in TNF-*-induced spondyloarthritis in mice, 2) identification of novel spondyloarthritis susceptibility genes in HLA-B27 transgenic rats, and 3) novel molecular therapeutic approaches.
NIAMS has outstanding training opportunities emphasizing bench-to-bedside approaches, vibrant Translational and Immunology Journal Clubs and seminar series, and multiple interactions between laboratories focusing on autoinflammatory disease mechanisms.
Talented, energetic, and enthusiastic applicants with a PhD degree in a relevant area, an MD degree with significant laboratory research experience, or MD/PhD degrees are sought. Positions are available immediately and applications will be considered on a rolling basis. Interested applicants should send their curriculum vitae and the names of three references to:
Robert A. Colbert, M.D., Ph.D.
E-mail: colbertr@mail.nih.gov
NIAMS/NIH
Bldg. 10/CRC, Room 1-5142
Bethesda, MD 20892
Phone: (301) 443-8935
Fax: (301) 480-5189
Posted: October 9, 2009
A postdoctoral position at the University of Alabama at Birmingham is immediately available to study lymphocyte development and members of a novel family of Fc receptor-like (FCRL) molecules. FCRLs possess tyrosine-based regulatory potential and are expressed by distinct populations of B cells and cytotoxic lymphocytes (Annu Rev Immunol. 2007;25:525-60 PMID: 17201682). Current work in the laboratory focuses on exploring their biological roles in human and mouse models as well as their importance in malignancies and autoimmune disorders.
A strong
background in basic cellular immunobiology is required. Familiarity with
molecular biology, flow cytometry, and biochemistry techniques are highly
desirable. Suitable candidates should be able to communicate well verbally
and work independently.
Ph.D. and/or M.D. degree is required. Applicants please send curriculum
vitae with a description of research interests and names of three references
with email addresses to:
Randall S. Davis, M.D.
Associate Professor of Medicine, Microbiology, and
Biochemistry & Molecular Genetics
University of Alabama at Birmingham
1825 University Blvd SHEL412
Birmingham, AL 35294-2182
TEL: (205) 934-1522
FAX: (205) 934-1875
Email: randall.davis@ccc.uab.edu
Posted: October 9, 2009
The Work:
A Postdoctoral Fellowship is available in the lab of Don J. Diamond,
Ph.D. The Division of Translational Vaccine Research has an opening for a
skilled postdoc fellow in T cell immunology with interests in therapeutic
cancer vaccines. Our current work involves developing both peptide and
molecular vaccines against tumor antigens involved in hematologic
malignancies. We have a strong group of virologists building the vaccines
and immunologists who evaluate them in mouse models and in human blood
specimens. The immediate need is to expand our work by developing tumor
models that can be used to demonstrate efficacy of the vaccines in support
of
To Apply: Please submit a statement of research interests and/or experience (evidence of writing and communication skills), a current curriculum vitae, and names and addresses of three references to Don J. Diamond, Ph.D., c/o: dpacker@coh.org EOE/AA
At City of
[KW: Los Angeles, California, LA, vaccine, T cell, immunology, cancer vaccine, oncology, cancer, peptide vaccines, molecular vaccines, tumor antigens, hematology, tumor models, WT1, PR3, survivin, blood, immunotherapy, cell biology, cellular immunology, molecular, transfection]
Posted: Posted: October 7, 2009
Postdoctoral positions in molecular and cellular immunology
Seeking highly motivated postdoctoral fellows with a desire to conduct research aligned with our laboratory’s goals. The overall goals of our laboratory are to understand why the immune system causes autoimmune diseases and to devise methods to predict and treat them. We develop and use mouse strains that provide models for human diseases such as lupus, rheumatoid arthritis, and epidermolysis bullosa. We use a combination of genetics, molecular biological and cellular immunological tools to dissect the molecular and cellular processes that cause these diseases. Finally, we study the mechanisms that affect the persistence of antibodies and antibody-based therapeutics. The information gained from all of these approaches is then used to devise possible therapeutic approaches with a keen eye on those that can be translated to humans.
Successful candidates should have received a recent Ph.D. or M.D., be committed for a minimum of 2 years, and have a strong record of training in molecular and cellular immunobiology and/or related areas. Please send your CV, statement of research accomplishments and interests, and contact information for 3 references by email to:
Derry Roopenian, Ph.D., Professor, The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609 * Ph: 207-288-6396 * Email: derry.roopenian@jax.org * Faculty Webpage: http://research.jax.org/faculty/derry_roopenian.html
Posted: Posted: October 7, 2009
POST DOCTORAL POSITIONS – Dendritic Cells in Viral Immunology
The Center for Vaccine Research at the University of Pittsburgh has openings for postdoctoral fellows to study the role of dendritic cells in transmission and immunopathology of dengue in humans, and the role of dendritic cells in the pathogenesis of HIV infection using the nonhuman primate model. Applicants must have an interest and relevant expertise in cellular and viral immunology. The positions are available immediately and are for an initial period of two years. The Center for Vaccine Research is housed in a state-of-the-art facility with research programs focused on HIV, dengue, influenza and other emerging infectious diseases and is part of a larger community at the University of Pittsburgh that currently ranks seventh nationally in NIH funding. Please send curriculum vitae and names and contact information of three references, preferably by email, to:
Simon Barratt-Boyes, BVSc, PhD, Dip ACVIM
Associate Professor
Center for Vaccine Research
University of Pittsburgh
9046 Biomedical Science Tower 3
3501 Fifth Avenue
Pittsburgh, PA 15261
Email: smbb@pitt.edu
Posted: Posted: October 2, 2009
Postdoctoral Position in Innate Immunity
The major interest of our lab is to study NADPH oxidase as a critical regulator of inflammation and host defense. NADPH oxidase is involved in host defense pathways, rapidly activated in response to certain microbial products, and converts molecular oxygen to superoxide anion and downstream reactive oxidant intermediates (ROIs). Chronic granulomatous disease is an inherited disorder of the NADPH oxidase characterized by severe bacterial and fungal infections (e.g., invasive aspergillosis) and by excessive inflammation. In addition to its critical host defense role, we found that NADPH oxidase also functions to restrain inflammation by modulating redox-sensitive innate immune pathways. NADPH oxidase also affects T-cell responses, including the balance between Th17 and regulatory T-cells. Our work has broad relevance to human diseases associated with inflammation, such as autoimmunity and tumor immunology. Indeed, several of the pathways that NADPH oxidase regulates are important in tumorigenesis and the tumor microenvironment (e.g., NF-κB, Nrf2, IL-17, Tregs), and are potential therapeutic targets. We have an NIH grant to further elucidate mechanisms by which NADPH oxidase regulates inflammation.
A postdoctoral position in our lab is immediately available. The applicant should be a graduating Ph.D. student or postdoctoral fellow with experience in Immunology. Strong laboratory experience in molecular and immunological techniques and in working with mice is required. The applicant should have a good publication record in relation to his or her level of training. Applicants must be U.S. citizens, permanent residents, or hold a valid visa for work in the U.S.
The mission of Roswell Park Cancer Institute (RPCI) is to understand, prevent and cure cancer. RPCI, founded in 1898, was one of the first cancer centers in the country to be named a National Cancer Institute-designated comprehensive cancer center http://www.roswellpark.org. The research in the Department of Immunology at RPCI runs the complete gamut from basic mechanisms of immune responses, through translational development of novel therapies, to clinical trials http://www.roswellpark.org/Research/Departments/Immunology.
Please e-mail a cover letter describing your research experience and career goals, your CV, and 3 letters of reference to: brahm.segal@roswellpark.org.
Brahm H. Segal,
MD, FACP, FIDSA
Associate Professor of Medicine
State University of New York at Buffalo
Chief, Division of Infectious Diseases
Roswell Park Cancer Institute
Elm & Carlton Streets
Buffalo, NY 14263
716-845-5721 (voice)
716-845-5777 (fax)
brahm.segal@roswellpark.org (e-mail)
Posted: Posted: September 29, 2009
A post-doctoral
research associate position is available immediately to study mechanisms
that determine the early host response to viral infection and allergen
exposure. Candidates (PhD, MD or equivalent) must have a strong background
in cellular and molecular immunology, experience in mouse models of disease,
cell culture and flow cytometry. Qualifications also include strong
interpersonal and organizational skills, excellent communication (written
and oral), ability to work independently, and commitment to laboratory
research. Applicants should submit a CV, preferably by email, statement of
research interests, and three references to:
Azzeddine Dakhama, Ph.D.
Associate Professor
Department of Pediatrics
National Jewish Health
1400 Jackson Street
Denver, Colorado 80206
Email: DakhamaA@NJHealth.org
Posted: September 29, 2009
We are looking for a highly motivated individual. The candidate must hold a doctor’s degree and have a background in biochemistry, cell-and molecular biology, immunology or a related field. Recent graduates are highly encouraged to apply. The candidate will work with a vibrant and multi-disciplinary group, and will have the opportunity to establish his/her own projects towards their own carrier development.
To apply, please contact Dr. Angela Dolganiuc, M.D., Ph.D., Assistant Professor, Department of Medicine University of Massachusetts Medical School, email: angela.dolganiuc@umassmed.edu.
Posted: September 29, 2009
E-mail: mullenh@health.missouri.edu; phone: 573-882-7150; fax 573-882-1380.
A postdoctoral position is available to participate in NIH funded research projects in the laboratory of Dr. Helen Braley-Mullen at the University of Missouri. The major focus of one project is to understand the mechanisms by which B cells regulate development and progression of autoimmune diseases using a mouse model of thyroiditis. The second project focuses on understanding the cellular and molecular mechanisms by which T cells and cytokines function to promote development of severe thyrocyte hyperplasia and fibrosis in IFNgamma-deficient NOD.h-2h4 mice. An individual could devote partial effort to both projects or 100% of their effort to the second project. Applicants must have recently completed a Ph.D and/or M.D. in Immunology or a closely related area, and have research experience in cellular immunology (essential for the first project) and/or molecular biology. Interested individuals should send a copy of their c.v., a summary of research interests and names of 2 or 3 individuals (with e mail addresses) who could be contacted for letters of reference. The preferred means for contact is e-mail. The University of Missouri is an equal opportunity employer.
Posted: September 25, 2009
POSTDOCTORAL POSITION: Inflammasome Regulation
Albany Medical
College, Albany, NY
A position is available immediately for a highly motivated and well-trained
postdoctoral fellow to contribute to an NIH-funded project addressing the
activation and regulation of the inflammasome by pyrin-only proteins using
both in vitro molecular biology and transgenic mice.
Requirements:
- Ph.D. in Immunology, Molecular Biology or related field.
- Strong technical background in molecular biology, cell biology and/or molecular immunology as demonstrated by publications in the applicant’s field of training.
- Strong practical knowledge of mouse immunology models. Candidates with prior experience in transgenic mouse models are especially encouraged to apply.
- Good command of English is required.
Salary will be commensurate with experience in accordance with the NIH scale.
To apply, send a letter of application, CV and the names of three references (including present research supervisor) to:
Jonathan A. Harton, Ph.D.
Assistant Professor
Center for Immunology & Microbial Disease
Albany Medical College
47 New Scotland Avenue, MC-151
Albany, NY 12208
email:
hartonj@mail.amc.edu
http://www.amc.edu/Research/IMD/imdresearcher.cfm?ID=211
Posted: September 22, 2009
A postdoctoral position is available immediately in the laboratory of Dr. Emilio Flano at the Center for Vaccines and Immunity to study the role of early innate immune mediators on T lymphocyte trafficking into the lung.
Our laboratory is interested in understanding the mechanisms of immune control of respiratory viral infections. The lung is the major portal by which microorganisms enter the body and acute respiratory infections are the leading cause of acute illness worldwide. We use primary airway epithelial cell cultures and mouse models of infection to study how the epithelium of the lung initiates and regulates local adaptive immune responses.
Applicants must have a Ph.D. with strong background in immunology. Candidates should e-mail their application, including curriculum vitae and the names and contact details of at least two references with whom they worked to brenda.anderson@nationwidechildrens.org.
Emilio
Flano, Ph.D.
Center for Vaccines and Immunity
The Research Institute at Nationwide Children’s Hospital
The Ohio State University
700 Children's Dr., WA 4015
Columbus, OH 43205
Phone (614) 722 2735
Fax (614) 722-3680
www.nationwidechildrens.org
Posted: September 18, 2009
A postdoctoral position is available immediately in the Feske lab at New York University Medical Center (NYUMC) to study the role and regulation of calcium signals and calcium channels in cells of the immune system. Experimental models focus on genetically modified mice and cells derived from these mice, especially T cells. Research interests include the molecular mechanisms regulating calcium signals in cells of the immune system and the role of calcium signals for immune processes like development and activation of T cells in vitro and in vivo in health and disease. For more information see Feske 2007 (Nat Rev Immunol. 7:690-702), Oh-hora et al. 2008 (Nature Immunol. 9:432-43) and http://pathology.med.nyu.edu/people/faculty/feske-stefan.
Requirements:
Highly motivated Ph.D., M.D./Ph.D. or M.D. with a solid background in
immunology. Expertise in the immunological analysis of mouse model systems
is requested and experience in transgenesis an advantage.
The Feske lab is part of a vibrant immunology community, the Experimental
Pathology Program and Cancer Institute at NYU Medical Center. It is located
in the new Smilow Research Center on the NYUMC main campus located in
midtown Manhattan. Subsidized housing for postdoctoral fellows is available.
Interested applicants should send a cover letter explaining relevant work
experience, a CV and the names, telephone numbers and e-mail addresses of
three references by e-mail to:
Dr.
Stefan Feske
Department of Pathology
NYU Medical Center, New York, NY
feskes01@nyumc.org
Posted: September 17, 2009
Peter R. Hoffmann, Ph.D., MSPH
Assistant Research Professor
Cell and Molecular Biology Department
John A. Burns School of Medicine
University of Hawaii
651 Ilalo Street
Honolulu, HI 96813
ph: 808 692-1510; fx: 808 692-1968
Posted: September 17, 2009
A postdoctoral position is available immediately to develop the trainee into an independent investigator by providing the opportunity to conduct original research, present findings in conferences, mentor students and prepare manuscripts and grant applications. Successful candidate will work with an exciting team of scientists and clinicians to generate novel immune-therapeutics and investigate their mechanisms of action. Current projects include DNA vaccines targeting Her-2 or TRAIL death receptor DR5, regulation of anti-tumor immunity versus autoimmunity, and modulation of signaling pathyways in regulatory T cell induction. Strong background immunology, molecular biology and experimental animal models will be required. For more information, see Whittington, PJ, et.al., Cancer Res. 68:7502, 2008, Radkevich-Brown, et.al., Cancer Res. 69:212, 2009 and Jacob, JB. et.al., J. Immunol. 182:5873, 2009. Please apply to http://jobs.wayne.edu by posting your CV and reference information to Post Doctoral Fellow posting # 036490 or send to:
Wei-Zen Wei, Ph.D.
Professor, Karmanos Cancer Institute
Professor, Dept. Immunology/Microbiology
Wayne State University
4129B Prentis Building, PR041M
110 E. Warren Ave.
Detroit, MI 48201
weiw@karmanos.org
Posted: September 16, 2009
Daniel L. Kaufman, Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA 90095-1735.
Posted: September 15, 2009
POSTDOCTORAL ASSOCIATE
A postdoctoral position is currently available in the Laboratory of B cell Immunoregulation, at the Duke Human Vaccine Institute (DHVI) to work on the role of B cells in the immune response to HIV. The project will specifically involve characterizing B cell immune modulation mechanisms in a variety of knock-in mouse models we have recently engineered to express light and/or heavy chains from the broadly neutralizing HIV antibody 2F5, and using these models to test if/what immunization regimens can elicit the production of broadly neutralizing antibodies. Qualified candidates should have experience in molecular and cellular immunology techniques and extensive experience using flow cytometry. Preference will be given to candidates with experience in characterizing mouse knockout/knockin models and performing mouse breedings and immunizations. A solid background in B cell immunology is also a plus.
The DHVI is a place of national and international leadership in the fight against major infectious diseases and is part of the Duke University Medical Center, located in the energetic and progressive Research Triangle area of North Carolina and was named by the Chronicle of Higher Education as one of the “2008 Great Colleges to Work For”. Duke is also ranked among the top 35 institutions for best places to work for Postdocs (The Scientist).
Highly motivated candidates with a Ph.D. and/or M.D. should send a cover letter, current CV, description of recent research work, and references to:
Laurent Verkoczy,
Ph.D.
Duke Human Vaccine Institute
Box 103020
106 Research Drive
Durham, NC 27710
Email:
dhvi.careers@notes.duke.edu --
Please note
Postdoc-Immunology in the subject line.
Duke University is an Equal Opportunity/Affirmative Action Employer.
Posted: September 15, 2009
A postdoctoral position is available in the Department of Immunology at Roswell Park Cancer Institute to study the complex interactions between tumors and the immune system. The initial project will characterize the lymphocyte makeup and functions (regulatory vs. effector lymphocytes) in the tumor micro-environment during tumor initiation and progression.
Requirements:
Highly
motivated PhD, MD, or MD/PhD with a solid background in immunology,
biochemistry, molecular and cell biology. Working experience in the
following areas is highly desired:
1. Immunology
2. Cancer biology
3. Mouse models of cancer
4. Gene targeting and transgenics
5. Bioinformatics
Preferred
candidates should be fluent in English. Please e-mail an application
including a cover letter describing current research, future interests,
expected start date, and CV, selected publications, names and contact
information of three references to:
Xuefang Cao, Ph.D.
Assistant Professor
Department of Immunology
Roswell Park Cancer Institute
Elm & Carlton Streets
Buffalo, NY 14263
Tel: (716) 845-3963
Fax: (716) 845-1322
Email: Xuefang.Cao@RoswellPark.org
Posted: September 14, 2009
The Topham Lab at the University of Rochester Medical Center is seeking a Postdoctoral Fellow with experience and training in immunology. Research projects will focus on human immune responses to influenza and influenza vaccines. The laboratory has established state-of-the-art technology to study human immunity, and is part of the network of NIH/NIAID Centers of Excellence in Influenza Research and Surveillance (CEIRS). Candidates must possess a PhD or MD degree. Recent graduates and experienced postdoctoral fellows with degrees and training in immunology or infectious diseases are sought. Salaries follow the NIH scale.
Interested applicants are encouraged to submit a curriculum vitae and names of references via email to:
Dr. David Topham -- email: david_topham@urmc.rochester.edu
Web: http://www.urmc.rochester.edu/labs/Topham-Lab/ and http://www.urmc.rochester.edu/influenza/.
Posted: September 14, 2009
Postdoctoral fellowships are immediately available to study leukocyte-endothelium interactions during rickettsial infections and vaccine development against Rickettsia using traditional mouse models and humanized mice.
Projects are funded by NIH and focus on the following aspects:
· Role of the endothelium in the regulation of the anti-rickettsial immune response
· Identification of rickettsial antigens recognized by T cells and B cells
· Optimization of a humanized mouse model of rickettsial infections
Candidates must have a Ph.D., D.V.M., or M.D. degree, a record of scientific accomplishment, and a strong background in immunology and/or rickettsiology. Experience with other BSL3 infectious agents, animal handling, or molecular biology are highly desirable.
Candidates must be U.S. citizens or permanent residents.
Please send CV, statement of research interests, and the names and contact information of 3 referees to:
Gustavo Valbuena, M.D., Ph.D.
Assistant Professor
Member, Center for Biodefense and Emerging Infectious Diseases
Department of Pathology
The University of Texas Medical Branch
gvalbuen@utmb.edu
Posted: September 9, 2009
A post-doctoral position is available to participate in immunological projects. Our lab’s research goal is to identify and characterize novel co-signal regulatory molecules through genetic, biochemical and immunological approaches, and manipulate these molecules to develop innovative and efficient immunotherapies against cancer, transplantation, autoimmunity and infectious diseases. An M.D. or Ph.D. in immunology, molecular biology, biochemistry or a related discipline is required. Previous experience of cytometry, lymphocyte culture, and mouse handling techniques would be anticipated. Salaries will be commensurate with experience and record of productivity. Please send your Curriculum Vitae and e-mail addresses of three references to: Dr. Koji Tamada at email address: ktamada@som.umaryland.edu.
Koji Tamada, M.D., Ph.D.
Associate Professor
University of Maryland School of Medicine
Marlene and Stewart Greenebaum Cancer Center
655 W. Baltimore St.
Bressler Research Building
Rm 9-051 (lab), Rm 9-043 (office)
Baltimore, MD 21201
Phone: 410-328-5114, Fax: 410-328-6559
Email: ktamada@som.umaryland.edu
Posted: September 4, 2009
A postdoctoral position is available immediately to study cell signaling in lymphocytes using autoimmunity, and cancer models. For more information see Venuprasad K et al. Nat Immunol. 2008; 9(3):245-53, Venuprasad K et al. J Clin Invest. 2006.116(4):1117-26, Chang L et al. Cell. 2006; 124(3):601-13, Jeon MS et al. Immunity. 2004 21(2):167-77. The applicant should have completed a Ph.D. and/or M.D. in Cell biology, Biochemistry, or Molecular Biology, The project involves gene cloning, siRNA, retroviral expression, cell signaling etc. The ideal candidate will have successful research experience in molecular biology, bio-chemistry and/or immunology. The successful candidate will be joining a very stimulating environment within the Karmanos Cancer Institute and Wayne State University. If interested, please send a CV and contact information of 2-3 references to Dr. Venuprasad K. Poojary at poojaryv@karmanos.org.
Posted: September 3, 2009
A postdoctoral position is available to study the regulation and functions of adenylyl cyclases in the immune system. We use a variety of biochemical and cell biology approaches to dissect the molecular mechanism of a novel regulation of adenylyl cyclase. In addition animal models are used to study the functions of adenylyl cyclases in immune responses and metabolism.
Applicants should have recently received their Ph.D. in the field of biochemistry, cell biology, immunology, or related areas. Experience with animal research is a plus. Strong candidates should be highly motivated and demonstrate independent research ability. English proficiency (spoken and written) is a must.
Interested applicants should send a CV, a brief statement describing their research interests and the names and contact information for three referees via e-mail to: lily.jiang@utsouthwestern.edu.
Dr. Lily Jiang
Assistant Professor
Department of Pharmacology
UT Southwestern Medical Center
6001 Forest Park Rd
Dallas, TX 75390-9196
(Ph) 214-645-6105
Posted: September 2, 2009
Posted: September 1, 2009
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