If you would like to include your position on this list, please contact us using these guidelines.

Derek Sant'Angelo
santandg@mskcc.org
Memorial Sloan-Kettering Cancer Center
1275 York Ave., Box 492
New York, NY 10065
Phone: 646-888-2335
Fax: 646-422-0470
Website: http://www.mskcc.org/mskcc/html/11172.cfm

Posted: September 3, 2010

Posted: August 30, 2010

Posted: August 30, 2010

The Indiana University School of Medicine-Terre Haute seeks a qualified candidate for a faculty position in Microbiology and Immunology, either tenure track or lecturer track.  We strongly encourage applications from women and minorities.  The candidate must have an M.D. or Ph.D. in Microbiology or Immunology and experience teaching Medical Microbiology and Immunology.  Postdoctoral experience is necessary for the tenure track but not for the lecturer track.  For the tenure-track, the teaching responsibility will be to direct the Medical Microbiology and Immunology courses.  The tenure track candidate is expected to develop his/her own area of research interest and to obtain external funding.  Preference will be given to candidates whose research interests match those at the Center, which include tissue regeneration, brain aging and neurodegenerative diseases, biophysical cell interactions, integrative/complementary medicine and chemical defenses and emerging infectious diseases. For the lecturer track, teaching responsibilities will be to direct the Medical Microbiology and Immunology courses, as well as participate in the teaching of other medical courses.  Rank and salary will be commensurate with experience.  Review of applications will begin immediately and will continue until the position is filled. Indiana University is an equal opportunity employer, M/F/D.

Please submit curriculum vitae, statement of research and teaching interests and the contact information for 3 references to:

Dr. Taihung Duong

Assistant Dean and Director

Professor of Anatomy and Cell Biology

Indiana University School of Medicine-Terre Haute

620 Chestnut Street

Holmstedt Hall 135

Terre Haute, IN 47809-9989

(812) 237-2777

(812) 237-7646 FAX

tduong@iupui.edu

Posted: August 30, 2010

The Benaroya Research Institute at Virginia Mason (BRI) is a center of scientific excellence in research and therapy of autoimmune diseases, such as diabetes, multiple sclerosis and arthritis, and promotes clinical and interdisciplinary research, particularly in cancer, neuroscience, and heart disease. BRI is a non-profit organization celebrating its 54th year as Washington State’s oldest medical research institute with over 200 employees and a $28 million budget for 2010.  BRI offers a competitive salary and excellent benefits.

Position: 10-51

Position: Postdoctoral Research Associate

Department: Kowdley Lab

Status: Full time

Responsibilities and Qualifications: The Postdoctoral Research Associate will be responsible for all aspects of the project to define novel serum biomarkers associated with PSC progression, presence of ulcerative colitis and cholangiocarcinoma and therapeutic effect of UDCA among subjects enrolled in a long-term study of the efficacy of high-dose ursodeoxycholic acid (28-30 mg/kg/d, UDCA for PSC.

The specific aims of the project are:

• Determination of the serum profile of 27 cytokine/chemokines in PSC patients using a multiplex platform.
   

• Global profiling approach in which we will assay 365 miRNAs in parallel using a microfluidic qRT-PCR platform to identify miRNA signature in peripheral blood that could distinguish between 1) early vs advanced PSC; 2) PSC±UC; 3) PSC± cholangiocarcinoma; 4) UDCA treated vs untreated.

Ph.D. is required with competency in all standard molecular biology techniques such as DNA, RNA, protein isolation, gene expression analyses, multiplex assays and familiarity with siRNA methodology etc.

For application instructions please visit http://www.benaroyaresearch.org/employment and quote reference number 10-51 in your cover letter.

EEO – M/F

Posted: August 30, 2010

Excellent communication skills are a requirement for this position. Salary commensurate with research experience. Please submit a single PDF file containing a brief cover letter, CV (indicating earned degrees), research experience, publications, and complete information for three referees to ssadegh@jhmi.edu.

http://pathology2.jhu.edu/ssnweb/index.html

References:

Kedar Narayan*, Chih-Ling Chou*, AeRyon Kim, Isamu Z. Hartman, Sarat Dalai, S. Khoruzhenko, & S. Sadegh-Nasseri. HLA-DM targets the hydrogen bond between the histidine at position 81 and peptide to dissociate HLA-DR­peptide complexes. (2007) Nature Immunology, 8, 92 - 100.

Dalai SK, S Mirshahidi, A.Morrot, F. Zavala, and S. Sadegh-Nasseri. Anergy in Memory CD4+ T Cells is induced by B cells. (2008) Journal of Immunology,
181(5):3221-31

S. Sadegh-Nasseri, Dalai, S.K., Korb Ferris, L.C. & Mirshahidi, S. 2010. Suboptimal engagement of the T-cell receptor by a variety of peptide-MHC ligands triggers T-cell anergy. Immunology 129, 1-7.

Isamu Z. Hartman*, AeRyon Kim*, Robert J. Cotter, Kimberly Walter, Sarat K. Dalai, Tatiana Boronina, David E. Lanar, Urszula Krzych, Robert N. Cole, and Scheherazade Sadegh-Nasseri. A novel Minimalist Cell-Free MHC Class II Antigen Processing System Identifies Immunodominant Epitopes from Protein Antigens. Nature Medicine (2010 - in press).

Posted: August 27, 2010

Postdoctoral Position:  Tumor immunotherapy

A postdoctoral position is available in the laboratory of Mark P. Rubinstein, Ph.D., in the Department of Surgery at the Medical University of South Carolina.  This position will involve developing methods for enhancing the efficacy of therapeutic dendritic cell vaccines against tumor using mouse models. A focus of these studies will be in enhancing the response of tumor-specific CD8⁺ T cells using combinations of chemotherapy, cytokines, and other molecules.

Candidates should have a Ph.D. and/or M.D. and relevant scientific experience. Please send 1) a cover letter summarizing your current and future research interests, 2) your CV, and 3) a list of 3 or 4 references. Please send these as PDF or word documents to: markrubinstein@musc.edu. 

Mark Rubinstein

Assistant Professor

Medical University of South Carolina

86 Jonathan Lucas Street, HCC512

Charleston, SC 29425

www.musc.edu

Posted: August 27, 2010

POST-DOCTORAL RESEARCH FELLOW

Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Hutchinson Center, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is the only National Cancer Institute (NCI)-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference.

A highly motivated post-doctoral research fellow is sought to join the laboratory of Dr. Thomas Spies at the Fred Hutchinson Cancer Research Center in Seattle, WA. Our laboratory studies the regulation of human tumor immunity and autoimmunity (lupus) by the stimulatory NKG2D lymphocyte receptor and its cell stress-induced ligands. Current emphasis is on mechanisms that promote NKG2D ligand-mediated immune suppression. We employ a broad range of experimental methods including polychromatic flow cytometry, assays of T cell functions, immunofluorescence imaging, and biochemical and molecular biology techniques including RNA knockdown. For further research information and a list of publications see http://labs.fhcrc.org/spies/index.html

We are looking for an enthusiastic scientist with a Ph.D. in Immunology or a related field, a record of productive research, and the ability to work independently as well as in collaborative research efforts. Further requirements are excellent organizational, and verbal and written language skills. Candidates for this full-time research position must be experienced in working with T cells, immunological assay techniques, polychromatic flow cytometry, and cell culture. Experience in DNA cloning/sequencing, PCR and QPCR, and RNA and protein gel electrophoresis and blot analysis is highly desirable.

Full-time position...Salary based on NIH scale + excellent benefits.

To apply for this position, please send your cover letter, curriculum vitae, and two letters of recommendation to:

Scott Canavera

Human Resources Specialist, J1-105

Fred Hutchinson Cancer Research Center

P.O. Box 19024

Seattle, WA 98109

Fax: 206-667-4026

Email: scanaver@fhcrc.org

Please reference position SC-23255. Electronic Submissions preferred.

The Fred Hutchinson Cancer Research Center and The Seattle Cancer Care Alliance are equal opportunity employers, committed to workforce diversity.

Posted: August 20, 2010

Posted: August 18, 2010

Postdoctoral Positions investigating CD4+ and CD8+ T cells responses

Emory University School of Medicine

Postdoctoral positions available in the lab of Brian Evavold investigating the mechanism of T cell responses to myelin and viral antigens.  Potential projects include i) 2-dimensional (2D) affinity of responding T cell populations during EAE or chronic viral (LCMV) infection; ii) enhancement of the CD8+ T cell response against viral escape mutants, and iii) elucidating the role of the SHP-1 tyrosine phosphatase in T cells.  The postdoctoral fellow will potentially use cell culture and cell-based assays, micropipette receptor ligand analysis, protein purification, flow cytometry, ELISA, molecular biology techniques, animal models, and patient samples to investigate the role of various components of the immune system in determining the outcome of autoimmune or viral infection

Preferred skills: The ideal candidate will have previous experience in small animal handling/care, an interest in immunology and virology and will be very organized, flexible and self-motivated.

Please email CV and the names of 3 references to: Brian Evavold, Department of Microbiology and Immunology  email: bevavol@emory.edu.

Posted: August 18, 2010

Posted: August 13, 2010

Dr. Christina C. Leslie, lesliec@njhealth.com, National Jewish Health, The Program in Cell Biology, Dept. Pediatrics, 1400 Jackson Street, K906, Denver, CO 80206. AA/EEO & Tobacco Free

Posted: August 13, 2010

Postdoctoral Research Position  

A postdoctoral research associate position is available immediately to study mechanisms that determine the outcome of early host response to respiratory viral infection and allergen exposure. Candidates (Ph.D., M.D., or equivalent) must have strong background in cellular and molecular immunology, experience working with animal models of disease, cell culture and flow cytometry. Qualifications also include strong interpersonal and organizational skills, excellent communication (written and oral), ability to work independently, and commitment to laboratory research. Applicants should submit a CV, preferably by email, and three references to: 

Azzeddine Dakhama, Ph.D.
Associate Professor
National Jewish Health
1400 Jackson Street
Denver, Colorado 80206
Email: DakhamaA@NJHealth.org

Posted: August 11, 2010

Project focuses on the roles of chemokines in neuroprotection and repair using in vivo models of neuroinflammatory diseases.

Candidate should have doctoral training in immunology, be an American citizen, and possess excellent communication and writing skills. Please send a CV and a list of references to:

Robyn S. Klein, M.D., Ph.D.
Associate Professor
Washington University School of Medicine
St. Louis, MO 63110
rklein@id.wustl.edu

Posted: August 11, 2010

Research positions at Northwestern University

An NIH funded postdoctoral research position is available immediately. Requirements include a Ph.D. and/or M.D. in immunology or other cell biological field with an outstanding publication record. We are particularly looking for candidates with strong research background in cellular immunology and autoimmune diseases, such as type 1 diabetes and rheumatoid arthritis, using mice as animal models. Ph.D students graduated within two years are particularly encouraged to apply.

The focuses of our research are the molecular mechanisms of the development, activation, differentiation and tolerance of both T- and B-lymphocytes, as well as the development of autoimmune diseases. Current ongoing research projects are 1) epigenetics in immune regulations, 2) ubiquitination and autoimmunity and 3) T-cell signal transduction and the allergic lung inflammation.

Please send your resume and names of three references of your current and previous mentors to:

Deyu Fang, Ph.D., Associate Professor, Department of Pathology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611-3008, E-mail: fangd@northwestern.edu.

Northwestern University is an affirmative action/equal opportunity employer.

Posted: August 10, 2010

Posted: August 10, 2010

Post-doctoral Scientist in Cystic Fibrosis and Calcium Signaling Research
University of Bretagne Occidentale, Medical Center – U613

A 12-month post-doctoral position in the area of ion channel physiology and calcium signaling funded by the Conseil Général du Finistère is available for January 2011 in the INSERM unit U613 located in the Medical Center of the University of Bretagne Occidentale in Brest (France).

This postdoctoral position is opened in the lab of Dr. Olivier Mignen to investigate the molecular and cellular mechanisms underlying calcium signaling in mammalian cells and its implication in Cystic fibrosis.

Our laboratory is mainly interested in understanding the molecular mechanisms underlying calcium entries in non excitable cells and their roles in health and disease. Calcium entry is essential for many cellular functions including gene expression, secretion, cell motility and cell proliferation and differentiation. We are investigating the molecular components and the control mechanisms of store dependent and store independent calcium entries.

The main objective of the project is to characterize in airway epithelial cells the calcium signaling pathways involved in ion secretion and the potential beneficial roles of their stimulation to counteract the defect of chloride secretion observed in cystic fibrosis. The postdoctoral scientist will also be involved in studies designed to identify protein partners of calcium channels involved in calcium entry and pharmacological modulators of these entries. The knowledge derived from our research may ultimately lead to design novel pharmacological agents to treat Cystic fibrosis. Our project combines different experimental approaches including live-cell imaging, biochemistry, molecular biology and electrophysiology.

Extremely motivated Ph.D.s (maximum of 4 years postdoctoral experience) with a strong background in molecular and cell biology are encouraged to apply. Candidates with demonstrated records in studying calcium signaling will be preferred. Experiences in electrophysiology would be an asset but is not required. The candidate should have proven skills in Western blotting, immunoprecipitation, real time PCR, immunofluorescence, immunohistochemistry, cell culture techniques and in vitro transfection. Additional preferred skills include live cell confocal microscopy and proteomics. Knowledge of the physiology of fluid-secreting epithelia will also be appreciated. The applicant must be enthusiastic with communication skills (English and/or French) in order to be able to join a young starting team located in an excellent environment of research with various state-of-the-art core facilities.

The applicant will collaborate with the other members of the unit and must show a high motivation interdisciplinary work. The applicant must have done its PhD outside Britany and defended his thesis less than 4 years ago.

Salary ~ 2000€/month.

Interested applicants should send a letter of application, curriculum vitae and the names, telephone numbers and e-mail addresses of three references by e-mail to: olivier.mignen@univ-brest.fr and aurelie.vandebrouck@univ-brest.fr. Please also indicate in your application:

1. your particular knowledge and enthusiasm regarding the topic and interest in this project - this is very important

2. your availability

3. your email address (for acknowledgements of applications)

4. three names for letters of recommendations

For additional questions and information:

Posted: August 9, 2010

The Henry M. Jackson Foundation (HJF) is seeking a Postdoctoral Fellow for the Military HIV Research Program (MHRP) located in Rockville, Maryland.  HJF provides scientific, technical and programmatic support services to MHRP (www.hivresearch.org). MHRP conducts research to develop an effective HIV vaccine and integrates prevention, diagnostics, treatment and monitoring as part of an international effort to protect US and Allied troops and reduce the impact of HIV infection worldwide. The program is a part of the Walter Reed Army Institute of Research.

MHRP recently led a clinical study that showed an investigational HIV vaccine regimen was safe and, for the first time, modestly effective in preventing HIV infection. It lowered the rate of HIV infection by 31.2% in a Phase III clinical trial involving more than 16,000 adult volunteers in Thailand. Although the efficacy is modest, this study represents a major scientific achievement that has important implications for HIV vaccine testing and development.

We need additional scientific talent to join our research team, as we build on the success of the Thai HIV vaccine study and pursue the development of other HIV vaccines.

A successful candidate will initiate and carry out HIV-1 vaccine research as part of an international collaboration of researchers. Specifically, they will design, develop, execute, and implement cellular immunology assays with the focus on HIV-1 vaccine development and HIV-1 pathogenesis that will lead to high impact scientific publications.

Responsibilities will include laboratory research that utilizes state-of-the-art cellular immunology experimental protocols focusing on the characterization of lymphocytes from HIV-1 vaccine cohorts or HIV infected individuals. In particular: intra-cellular cytokine production, memory and activation phenotypes, NK and NKT cell phenotype and functions.

Requirements: Strong knowledge and hands on experience in flow-cytometry; ability to analyze and interpret data using Flowjo software; ability to draft manuscripts; ability to work as a team player in highly interactive and multi-disciplinary research environment.

Minimum Education/Training Requirements: PhD in immunology or related scientific discipline; 1-2 years of experience in immunology laboratory with focus on flow-cytometry.

Please apply on-line at www.hjf.org/careers. Click “Advanced Search” and enter job number 205233 in the Job Opening ID box.

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) is a congressionally authorized, not-for-profit corporation that provides unparalleled scientific and management services to military medical research and education programs worldwide. Our mission is to advance military medical research. AA/EEO

For a comprehensive list of our benefits, please visit: http://www.hjf.org/careers/benefits.html.

Posted: August 3, 2010

Posted: August 3, 2010

Posted: August 2, 2010

NK Cells and Virus Immunity
University of Virginia

A postdoctoral position is available immediately for 3-5 years, to study the effects of MHC polymorphism on NK cell effector functions and regulatory mechanisms which shape NK interactions with immune cells, NK resistance to virus infection, virus persistence and virus induced morbidity and mortality. Genetic, molecular and cellular methods are used in the laboratory to determine the immunological and mechanistic basis of NK cell-mediated virus resistance and further impacts on immune cell function and virus immunity. Applicants must have a Ph.D. or M.D. degree, a strong background in molecular and cellular immunology or virology and less than 5 years of postdoctoral experience. Thorough knowledge of English and excellent written and oral communication skills are required. To apply, please email your CV, statement of research interests and contact information of three references to:

Michael G. Brown, Ph.D. - mgb4n@virginia.edu
University of Virginia
Beirne B. Carter Center for Immunology Research
PO Box 801386
Charlottesville, VA 22908-1386

Positions opened until filled.

The University of Virginia is an Equal Opportunity/Affirmative Action Employer

Posted: July 30, 2010

The University of Virginia, Beirne B.Carter Center for Immunology Research and Department of Pathology, has a postdoctoral position available immediately in Immunology of Reproduction with Ph.D. and/or M.D. degree to investigate the mechanism of autoimmune disease induction and its regulation.  Our NIH sponsored research uses clinically relevant autoimmune models to elucidate cellular and molecular mechanisms of disease development and progression, and define critical regulatory mechanisms including antigen specific regulatory T cells as suitable therapeutic targets.  Candidates must have a publication record in an International or National Journal, and are experienced in cellular immunology and molecular research approaches. 

To apply, please email or send your CV, statement of research interests and contact information of three references to:

Kenneth Tung, MD
Email: kst7k@virginia.edu
University of Virginia Health System
Beirne B.Carter Center for Immunology Research
PO Box 801386
Charlottesville, VA 22908-1386

Position is open until filled.

The University of Virginia is an Equal Opportunity/Affirmative Action Employer

Posted: July 30, 2010

Postdoctoral Research Positions in Skin and Liver Inflammation 

Several positions are available in the laboratory of Dr. Liselotte E. Jensen to study the roles epithelial cells play in orchestrating innate and adaptive immune responses during infections and chronic diseases of the skin and liver. Mechanisms of intracellular signal transduction and intercellular communication will be examined in both in vitro and in vivo models. Primary emphasis will be on interleukin-1 and toll-like receptor signaling but other pathways will also be explored. 

The studies aim to characterize novel regulatory mechanisms of inflammation and dysfunctional pathways associated with chronic disease. The ultimate goals are to identify promising novel therapeutic targets and agents. 

The successful candidates may be involved in the following, and other, ongoing studies: 

1)             Cytokine signaling in epithelial cells during viral and bacterial infections (see, for example, J Invest Dermatol, 2010, 130:1866-76)
2)             Dysregulated intracellular signaling in chronic inflammatory conditions such as psoriasis, eczema and hepatitis (e.g. Cell Signal, 2009, 21:685-94)
3)             Functional characterization of Pellino proteins (e.g. Structure, 2008, 16:1806-16; J Immunol, 2003 171:1500-6; FEBS Lett, 2003, 545:199-202)             

Requirements:

• A Ph.D. in Immunology, Microbiology and/or Molecular Biology.

• Peer-reviewed publications in the field(s) of Immunology, Microbiology and/or Signal Transduction.

• Experience with molecular biology, biochemistry, immunology, histology, signal transduction, cell culture methods and animal handling (mice) and breeding.

• Excellent written and oral communication skills in English. 

Additional experience with inflammatory in vivo models is highly desirable. 

Send cover letter, statement of research interests, CV and contact information for 3 references to:

Liselotte E. Jensen, Ph.D., Department of Microbiology and Immunology and Autoimmunity Center, Temple University School of Medicine, 1158 MERB, 3500 N Broad Street, Philadelphia, PA 19140. E-mail: liselott@temple.edu.

Posted: July 28, 2010

Posted: July 27, 2010

Posted: July 22, 2010

Post-Doctoral Position – 3 years funding

Investigator: Peter Velázquez, Ph.D.
Department of Microbiology and Immunology
Indiana University School of Medicine – South Bend, South Bend, IN

Our lab is interested in single- and multi- photon applications in intravital microscopy. We study T cell patrolling of the intestine and gut associated lymphoid tissue (GALT). Current studies are aimed at understanding the role innate sensors and antigen specificity play in modulating the T cell patrolling. We aim to understanding how these processes affect tumor formation and susceptibility to Inflammatory Bowel Disease (IBD).

Competitive candidates will have a strong background in Immunology, publication record in peer-reviewed journals, have (or near) completed Ph.D.

Please submit CV and contact information to:
Peter Velázquez, Ph.D. - Assistant Professor
Indiana University School of Medicine – South Bend
Department of Microbiology and Immunology
1234 Notre Dame Ave, RCH 151
South Bend, IN 46615
pvelazqu@iupui.edu

Posted: July 14, 2010

Post-Doctoral Position

Investigator: Xian John Zhang, Ph.D.
Division of Rheumatology and Immunology
Department of Medicine
Medical University of South Carolina, Charleston, SC

POSTDOCTORAL POSITIONS are immediately available for research on autoimmune disease and cancer immunology. Projects include:

1. Identifying the new mechanisms of glomerulonephritis development through studies in both murine model systems and in vitro cell culture.
2. Identifying new markers for ovarian cancer.

Candidates must have a Ph.D. or equivalent degree with a very strong background in immunology and/or molecular biology and biochemistry. Experience in molecular biology, murine models of disease, cellular and molecular immunology, biochemistry, and/or gene expression analysis is preferred. A highly motivated candidate who is able to plan and design projects independently is welcome. Located in Charleston, South Carolina, Medical University of South Carolina provides top programs for postdoctoral training, in an academic environment with competitive salary.

Please send curriculum vitae and contact information for three professional references to Dr. John Zhang (zhangjo@musc.edu).

Posted: July 14, 2010

Post-Doctoral Position

Investigator: Alanna Ruddell, Ph.D.
Division of Human Biology
Fred Hutchinson Cancer Research Center, Seattle, WA

About Us

Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center's four scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Hutchinson Center, in collaboration with its clinical and research partners, the University of Washington and Children's Hospital and Regional Medical Center, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference.

An NIH NCI-funded postdoctoral position is available at the Fred Hutchinson Cancer Research Center in Seattle, WA, USA, for a candidate to investigate immune and lymphatic system interactions in cancer. Dr. Alanna Ruddell's lab in the Division of Human Biology performs interdisciplinary research on mouse models of cancer. Our discovery of sentinel lymph node lymphangiogenesis and increased lymph drainage in response to cancer provides new insights to the host immune responses supporting tumor growth and metastasis. Our current research projects are focused on understanding the cross-talk between the immune and lymphatic systems in cancer and during the immune response, using transgenic mice as a model system. While our studies are fundamental and discovery-based, these projects are directed toward translational applications in the clinic.

Responsibilities

The postdoctoral fellow will investigate immune cell involvement in sentinel lymph node metastasis in mouse cancer models and in human cancer patients using a variety of techniques including immune cell purification and analysis, transplantation, optical imaging, microscopy, and molecular and cellular biology. The FHCRC provides one of the nation's top programs for postdoctoral training, in an academic environment with clinical and translational research opportunities.

Qualifications

>A highly motivated candidate is sought with a recent PhD in a relevant field, preferably including immunology training. Experience in cancer biology is also desirable. The candidate should possess strong scientific credentials and work ethics. He/she will have an excellent oral and written command of the English language.

How to Apply

To apply for position #23194, please email your cover letter, CV, and contact information for three professional references to scanaver@fhcrc.org, or mail to Scott Canavera, Scientific Recruiter, FHCRC, 1100 Fairview Avenue N., J1-105, PO Box 19024, Seattle WA 98109 USA

Posted: July 12, 2010

Post-Doctoral Position

Investigator: Gislâine A. Martins, Ph.D.
Department of Biomedical Science/Medicine/Inflammatory Bowel and Immunobiology Research Institute (IBIRI)
Cedars-Sinai Medical Center, Los Angeles, CA

NIH-funded POSTDOCTORAL POSITION available in the laboratory of Dr. Gislaine Martins at the Department of Biomedical Science/ Medicine/IBIRI at the Cedars-Sinai Medical Center, Los Angeles, to study molecular regulation of T cell effector function in the intestinal mucosa.

Current areas of specific interest include the role of a transcriptional repressor in preventing mucosal T cell hyper responsiveness (Nat Immunol. 2006 May;7(5):457-65.; J Exp Med. 2008 Sep 1;205(9):1959-65) and identification of new pathways regulating mucosal T cell function.

Candidates should have a demonstrated record of significant scientific accomplishment at the graduate or postdoctoral level, and a solid background in immunology and/or molecular biology is preferred. Specialty background in mucosal immunology and in vivo mice models preferred.

Please send curriculum vitae, addresses of three references and a letter describing your research interests to: martinsg@cshs.org

Posted: July 12, 2010

Post-Doctoral Fellow- Innate and Acquired Immunity

Respiratory virus-induced Disease

The laboratory focuses on research examining the mechanisms of viral-induced pulmonary disease (RSV, Influenza) that centers on TLR, Notch and novel signaling processes that regulate innate and T cell activation. The topics available for study include (but are not limited to) development and regulation of Th2 and Th17 immune environments related to pulmonary diseases, including asthma and COPD.  Projects involve both in vivo and in vitro modeling of immune cell function.  The laboratory environment has been established to allow scientific development and professional growth leading to an independent career. 

Competitive Candidates will have attained a Ph.D. with expertise in molecular and cellular Immunology and a proven publication record with strong oral and written communication skills.

Qualified Applicants should submit their CV and contact information for 3 references by email to:

Nicholas Lukacs, Ph.D.

Professor of Pathology

University of Michigan

Ann Arbor, MI

nlukacs@umich.edu

Posted: July 2, 2010

Posted: July 1, 2010

USDA POSTDOCTORAL FELLOWSHIP IN VIRAL IMMUNOLOGY

Eastern Long Island, NY or Southeastern Connecticut

PLUM ISLAND ANIMAL DISEASE CENTER, Agricultural Research Service

A postdoctoral research fellowship in veterinary immunology is available for 2+ years for the study of early immune responses of cattle after infection with foot-and-mouth disease virus (FMDV). Ongoing work will include understanding lymphocyte biology, innate and adaptive immune responses in vivo, and targeting methods of inducing rapid protection against infection.

Experience in studying immune responses in cattle is required. In addition, basic knowledge of molecular biology, virology, flow cytometry and tissue culture is desired. This work is carried out in BioSafety Level 3 (BSL-3) containment in modern, well equipped laboratory space. The facility has 14 senior scientists with postdoctoral fellows, graduate students and extensive support personnel. Animal facilities with the capacity to house livestock are also BSL-3. The position requires security clearance under the select agent program.

Plum Island is located off the eastern tip of Long Island, requiring daily travel by government provided ferry from either Orient Pt., NY or Old Saybrook, CT. This position is available immediately. Funding is for 2 years with the opportunity of extension based on progress and performance. Stipends range from $60,000 to $75,000/yr, depending on experience and qualifications. Please send a copy of your curriculum vitae and a statement of interests to:

Dr. William T. Golde 

Plum Island Animal Disease Center

ARS, USDA

P.O. Box 848

Greenport, NY 11944

 (631) 323-3249

william.golde@ars.usda.gov

web site: www.ars.usda.gov/plum/

Posted: July 1, 2010

Posted: June 29, 2010

Postdoctoral Position in Immunology at New York University Medical Center

A postdoctoral positions is available in the lab of Dr. Stefan Feske lab at New York University Medical Center (NYUMC) to study the role and regulation of calcium channels in cells of the immune system. Experimental models in vivo models of infection and autoimmunity using Orai and Stim knockout mice. Other projects in the lab focus on the molecular mechanisms regulating calcium channel function using cell biological and imaging methods and analysis of human patients with defects in calcium signalling.

For more information see Feske 2007, Nature Rev Immunol. 7:690-702; Oh-hora et al. 2008, Nature Immunol. 9:432-43; Kawasaki et al. 2009, BBRC 385:49–54; 10. Picard et al. 2009, N Engl J Med. 360:1971-80. Feske 2009, Immunol Rev 231:189-2009.

Successful applicants will have a PhD, MD/PhD or MD with a solid background in immunology. They should be highly motivated and have expertise in the immunological analysis of mouse model systems, a background in developing or using gene-targeted mice and be able to work independently. Excellent written and oral English skills are required.  

The Feske lab is part of a vibrant immunology and research community at NYU Medical Center. We are located in the new Smilow Research Center on the NYUMC main campus in midtown Manhattan.

Interested applicants should send a cover letter explaining relevant work experience, a CV and the names, telephone numbers and e-mail addresses of three references by e-mail to:

Dr. Stefan Feske

Department of Pathology

NYU Medical Center, New York, NY

Email: feskes01@nyumc.org

Website: http://pathology.med.nyu.edu/people/faculty/feske-stefan

Posted: June 29, 2010

Posted: June 25, 2010

Posted: June 25, 2010

We are looking for highly motivated person(s) with research experience in the areas of immunology and/or  virology to participate in research projects on HIV/AIDS, Dengue pathogenesis and immunity. Candidates with experience in cellular immunology of viral infections are preferred. State-of- the art technologies encompassing novel humanized mouse models, lentiviral vectors, RNAi, and stem cells are put to use to solve important problems. (Representative work: Anderson et al, 2007 Molecular Therapy 15:1182-88, Kuruvilla et al, 2007 Virology 369:143-152, Bandi & Akkina, 2008 AIDS Research and Therapy 5:1, Zhou et al, 2009  Nucleic Acids Res 37:3094-3109, Berges et al, 2010 Virology 397:100-103,.  Capacity for problem solving and ability to interact productively with colleagues are important.

Please apply before July 31, 2010, for full consideration although applications will be processed until suitable candidates are identified. Please send a letter of application together with a list of 3 references to the email address below mentioning Akkina Lab.

Ramesh Akkina, DVM, PhD
Dept. Microbiolgy, Immunology, and Pathology
1619 Campus Delivery
Colorado State University
Fort Collins, CO 80523-1619
Tel #  (970) 491 1009
Email: remling@colostate.edu
 
CSU is an Equal Opportunity Employer

Posted: June 24, 2010

Posted: June 24, 2010

Postdoctoral Position at the University of Chicago

A postdoctoral position is available in the Section of Nephrology of Department of Medicine at the University of Chicago.

This position is available immediately to study molecular mechanisms of T cell activation and autoimmunity. The candidates must have M.D., Ph.D. or both with a strong background in cellular and molecular immunology. Experience with murine autoimmune disease models, flow cytometry, and molecular biology techniques is desirable.

Candidates should send their letters of interest outlining their research interests and career goals, curriculum vitae, and list of three references to:

Jian Zhang, M.D.
Section of Nephrology
Department of Medicine
The University of Chicago
5841 S. Maryland Ave., MC 5100, Suite S-521
Chicago, IL 60637

Tel: 773 702 4764

Fax: 773 702 5818

E-Mail: jzhang@medicine.bsd.uchicago.edu

Posted: June 22, 2010

Immunology and Cancer

NIH-funded postdoctoral position is available at the Boston University School of Medicine, Department of Pathology and Laboratory Medicine.

Position available starting September 1^st to study gene regulatory mechanisms involved in T cell development and leukemogenesis focusing on the role of Ikaros in a laboratory that is moving from Chicago to Boston.  Opportunity exists to create a new gene-targeted mouse model.  The applicant must have recently completed a Ph.D. in biological sciences.  Expertise in flow cytometry, tissue culture and mouse handling is preferred. The successful candidate must be independent, have strong written and verbal communication skills, and first-author publications. 

Must be U.S. citizen or permanent resident.

Interested applicants should send a cover letter, CV, summary of previous research experience, and three letters of recommendation to Dr. Susan Winandy at s-winandy@northwestern.edu.

Some select publications:

1) Chari, S. and S. Winandy. (2008) Ikaros regulates Notch target gene expression in developing thymocytes. The Journal of Immunology 181:6265-6274

2) Umetsu, S.E. and S. Winandy. (2009) Ikaros is a regulator of Il10 expression in CD4+ T cells. The Journal of Immunology 183: 5518-5525

3) Chari, S., Umetsu, S.E. and S. Winandy. (2010) Notch target gene deregulation and maintenance of the leukemogenic phenotype do not require RBP-Jk in Ikaros null mice. The Journal of Immunology 185:410-417

Posted: June 22, 2010

Jose R. Conejo-Garcia, M.D., Ph.D.. Current address: Dartmouth Medical School, Department of Microbiology and Immunology, 640W Borwell, HB 7556; 1 Medical Center Dr., Lebanon, NH-03766.

email preferred: jrcg@dartmouth.edu
phone: (603)650-6822
Fax: 603-650-6223

Posted: June 21, 2010

POSITION ANNOUNCEMENT

Post Doc Associates – Research Positions in Applied Virology

Emerging Pathogens Institute

Department of Environmental & Global Health (EGH), College of Public Health & Health Professions

University of Florida, Gainesville, FL

Salary: $37,000-47,000/year, plus post doctoral associate benefits of UF

Position open until filled

Applications are invited for post-doctoral applied virology positions at the University of Florida’s Emerging Pathogens Institute (EPI).  The scholars will develop and manage applied studies of viral diseases.  As many as four post-doctoral scholar positions are available.

UF’s EPI is a national model for using interdisciplinary research methods to identify, prevent and treat human, animal and plant pathogens.  The EPI has BSL2, BSL2⁺Ag, and BSL3 laboratory facilities and state-of-the-art virology equipment.  Current projects include epidemiological of zoonotic diseases including avian influenza in six countries.  EPI research is being expanded to other pathogens, some arboviral, some select agents, and some international in scope.

Applicants should have graduate training in applied virology, epidemiology, and biostatistics with a PhD in a related field.  Applicants should have experience conducting applied virology or epidemiological studies of infectious diseases.  BSL3 experience is a plus.  Applicants should have proven skills in verbal and written communication and be able to work with considerable independence. 

These positions are jointly supported by the EPI (http://www.epi.ufl.edu), and the Department of Environmental and Global Health (EGH, (http://egh.phhp.ufl.edu) in the College of Public Health and Health Professions.  The University of Florida is a major, public, comprehensive, land-grant, research university. With an enrollment of more than 50,000 students annually, UF is home to 16 colleges and more than 150 research centers and institutes.  The EGH is a hub of collaboration among University of Florida scientists who are interested in the effects of the environment on human health. Factors in the air, soil, and water that threaten health are rarely contained within artificially drawn political borders.

Applicants will be expected to develop, execute, and publish applied virology research studies under the guidance of Professor and Department of Environmental and Global Health Chair Gregory C. Gray, MD, MPH.

The position is initially for one year, with the possibility of extension to an additional year upon mutual agreement.  The start date is flexible between Summer-Fall 2011.

Interested professionals are advised to electronically submit the following items: (1) cover letter; (2) curriculum vitae; (3) two letters of reference; and (4) up to two representative publications.  Please submit materials to Jessie Runge (jrunge@phhp.ufl.edu).  Review of applications will continue until successful candidates are identified.  Women and minorities are encouraged to apply.  Questions may be directed to:

Jenney K. Lazzarino, MS 
Research Program Assistant
Email Jlk@phhp.ufl.edu
Dept. of Environmental and Global Health
University of Florida

The University of Florida is an equal opportunity, equal access, affirmative action employer.

The Government under the sun laws of Florida require that all documents relating to the search process, including letters of application/nomination and reference, except transcripts, be available for public inspection. Persons with disabilities have the right to request and receive reasonable accommodation.

Posted: June 14, 2010

A postdoctoral fellow or research associate position is available at the University of Texas Health Science Center to study transplantation immunology. We are investigating the immunologic mechanisms underlying graft and/or tumor rejection. Our studies have largely focused on adaptive immunity including memory and regulatory T cells using a mouse model (J. Immunol., 2008, 180:113; J. Immunol., 2007, 178:4260; and JCI, 2004, 113:310). This position requires hands-on experience in molecular biology and immunologic assays etc. Experience in small rodent surgery is a plus.

The Health Center is a component of the University of Texas System. In contrast to other Midwest cities, Tyler is located 100 miles east of Dallas amid beautiful lakes and piney woods of East Texas. Campus housing is especially affordable while salary remains competitive.

If interested, please forward your CV, including a list of publications and names/contacts of two referees, by e-mail to the contact above.

Posted: June 14, 2010

The Biomedical Research Centre, University of British Columbia, Vancouver (http://www.brc.ubc.ca) The BRC is an interdisciplinary research centre which gathers into an open design laboratory, the research groups from different Departments of the Faculties of Medicine and Science. The trainees in these groups work alongside each other, exchanging knowledge and techniques. The BRC has state-of -the art core facilities including those for cell-sorting, proteomics and mouse genetics.

Posted: June 11, 2010

Postdoctoral Position at the DEL E. WEBB NEUROSCIENCE, AGING AND STEM CELL RESEARCH CENTER, La Jolla, California

Molecular Basis and Treatment of Neurodegenerative Diseases, including HIV-1-associated neurocognitive disorder
Principal Investigator: Drs. Stuart A. Lipton and Shu-ichi Okamoto

Duties & Responsibilities: Postdoctoral positions are available for a highly motivated candidate with an experimental background and the ability to work independently. Our research aims to understand the molecular and cellular mechanisms of neurodegenerative diseases and apply the basic knowledge to develop new treatments for neurodegenerative diseases. Experience with cell culture, molecular biology techniques, rodent handling, or chemokine/HIV-1-associated projects is desirable, but not essential.
 

For more information regarding our research, please visit: http://www.sanfordburnham.org/default.asp?contentID=242 

Requirements: Candidates must have a Ph.D. or M.D./Ph.D. in Cell/Molecular Biology, Immunology, Virology, or Equivalent. Excellent interpersonal and communication skills are required. Interested applicants should submit a copy of their CV and contact information (email address and phone number) of three references to: Dr. Scott McKercher, scottmk@sanfordburnham.org.

Posted: June 11, 2010

Postdoctoral Position in Immunology, Center for Cellular and Molecular Immunology, University of Missouri

Available immediately to study mechanisms governing the differentiation and function of CD4 T lymphocytes and the roles that these cells play in control of autoimmunity and maintenance of immune homeostasis at environmental interfaces. The applicant must have recently completed a PhD or equivalent in Immunology, Biochemistry, Molecular Biology, Genetics, or a related field.  The ideal candidate will have expertise in flow cytometry, tissue culture, molecular biology, mouse handling, and an interest in cytokine signaling and epigenetic mechanisms of gene regulation. The successful candidate will be joining a young, dynamic environment within the Center for Cellular and Molecular Immunology at the University of Missouri in Columbia.

Posted: June 9, 2010

The applicant will work in a new team headed by Dr. M. Si-Tahar and focused on host-pathogens interactions mechanisms in the lung mucosa.

Capital of the Loire Castels Valley, Tours is also turned to the future. The city is increasing the number of its research centres, especially medical and pharmaceutical laboratories.

The position is available for a motivated candidate to study innate immune response to influenza virus and/or nosocomial bacteria. She/he will use both in vitro (primary cells and cell lines) and in vivo (murine) models. (For references see: J. Biol. Chem. (2005), PLoS pathogens (2006), PLoS one (2009), J. Immunol. (2007, 2008 and 2009)).

The candidate should be qualified in immunology and/or virology or bacteriology. Experience with cell signalling experience would be an advantage but is not mandatory.
The position is available for 12 months (renewal will depend on further funding). Due to the financial source restrictions, only NON-French individuals (less than 35 years) may apply for this position.

Interested individuals, please send a CV, a letter outlining research experience and skills, and names and addresses of two references to:

Dr. M. Si-Tahar
Tel : (33-1)-44-38-91-05
E-mail : sitahar@pasteur.fr

Posted: June 8, 2010

Posted: June 8, 2010

Chao-Lan Yu, Ph.D.
Email: chaolan.yu@rosalindfranklin.edu
3333 Green Bay Rd, North Chicago, IL 60064, USA
Phone: 847-578-8333 * Fax: 775-206-3170

Department web address:
http://www.rosalindfranklin.edu/dnn/chicagomedicalschool/home/CMS/Microbiology/tabid/846/Default.aspx

Posted: May 24, 2010

POSTDOCTORAL POSITION 

A postdoctoral position is currently available in the laboratory of Dr. Marlene Bouvier in the Department of Microbiology and Immunology at the University of Illinois at Chicago. The project involves molecular- and cellular-based studies to study 1. key events in the class I antigen presentation pathway and 2. mechanisms of viral immune evasion. Qualified individuals should have a Ph.D. in molecular or cellular immunology, molecular or cellular virology, biochemistry, or biophysics. It is expected that applicants are able to work at the bench independently, interpret data, troubleshoot their experiments, and write manuscripts. Excellent communication skills are a requirement for this position. Salary commensurate with research experience. Please submit a single PDF file containing a brief cover letter, CV (indicating earned degrees), research experience, publications, and complete information for three referees to mbouvier@uic.edu

http://www.uic.edu/depts/mcmi/research.htm#bouvier

References:

Chen, M. and Bouvier, M. (2007) Analysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection. EMBO J. 26: 1681-1690.

Liu, H., Fu, J., and Bouvier, M. (2007) Allele- and locus-specific recognition of class I MHC molecules by the immunomodulatory E3-19K protein from adenovirus. J. Immunol. 178: 4567-4575.
 

Sadegh-Nasseri, S., Chen, M., Narayan, K., and Bouvier, M. (2008) The convergent roles of tapasin and HLA-DM. Trends Immunol. 29: 141-147.

Hansen, T. H. and Bouvier, M. (2009) MHC class I antigen presentation: learning from viral evasion strategies. Nat. Rev. Immunol. 9: 503-513.

Posted: May 13, 2010

POST-DOCTORAL POSITION

Harvard Medical School/Brigham and Women’s Hospital

Cutting edge projects focusing on the mechanisms of autoimmune disease/inflammation. These projects include novel pathways that regulate macrophages, and T cells, macrophage biology linked to autoimmune disease, determining the unique and shared role of the principle macrophage developmental molecules in immune mediated inflammation, and the power of the programmed death pathway in regulating tissue injury. Furthermore, studies focus on kidney regeneration mediated by resident cells and macrophages. Unique transgenic strains and knockout mice with reporter genes have been constructed on lupus susceptible strains for these projects. These projects dissect the basic mechanisms of autoimmune disease (kidney, skin, heart) and have human translational components.

Experience:

Immunology, and/or Molecular biology and Cell Biology

Knowledge of histopathology desirable

Mouse systems

Computer literacy is necessary

Desired:

Responsible, hard-working individual who is able to multi-task and to work independently

MD, or PhD required, position for two years or longer within the Department of Medicine, Brigham and Women’s Hospital.

Please send three references.

Interested candidates contact: Dr. Vicki Rubin Kelley, Harvard Institutes of Medicine, 4 Blackfan Circle, Boston, MA 02115; FAX 617-525-5830; e-mail: vkelley@rics.bwh.harvard.edu

Posted: May 13, 2010

Research Associate/Postdoctoral Position
Department of Microbiology, University of Virginia 

The successful candidate will be performing research on elucidating the mechanisms of Bacillus anthracis pathogenesis in a mouse model of infection in the rapidly growing dynamic multidisciplinary lab of Dr. Ian J. Glomski. The project focuses on the development of novel imaging technologies with a diverse group of microbiologists, immunologists, radiologists, chemists, and physicists residing in multiple departments throughout the University of Virginia Health System and applying these technologies to analyze the interaction of B. anthracis with the immune system.  

The candidate must have a Ph.D. or equivalent, have extensive experience in working with mice (including husbandry, anesthesia, dissection, organ/cell isolation, and multiple forms of parenteral inoculation) plus mastery of microbiological and cell biological techniques (including sterile technique, genetic manipulation, cell purification, tissue culture, and flow cytometry), and comfort working with radioactivity and infectious agents. The ability to function independently yet work well with a diverse group of scientists and students is a must. Furthermore, the candidate must be able to successfully pass a security risk assessment (SRA) performed by the Federal Bureau of Investigation.  

The candidate is expected to use the first year of funding to obtain preliminary data to support their application for support from sources within UVA, such as training grants, or externally, such as from the NIH or private organizations, to fund subsequent years of research within the lab.  

If qualified, please complete a Candidate Profile by going to https://jobs.virginia.edu/ and search on posting number 0605391. Please attach a current CV, a cover letter stating why you are qualified for this position, and the names and contact information of 3 references.  

The position will remain open until filled.  

The University of Virginia is an equal opportunity/affirmative action employer. 

Posted: May 13, 2010

NIH-funded postdoctoral position is available at the University of Maryland School of Medicine

Successful candidate will study molecular mechanisms of TLR signaling. The project involves identification of interfaces that mediate signal-dependent recruitment of TLR adapters to TLRs with the aim being to understand better the architecture and mechanisms of assembly of TLR signaling complexes.
 

Requirements:

• Recent PhD in Molecular and Cellular Biology, Biochemistry, or Immunology.
• A peer-reviewed publication that demonstrates candidate’s proficiency in “wet-bench” cell signaling work.
   

Preference will be given to applicants with experience in screenings for inhibitors of cellular signaling, quantitative real-time PCR, Western analysis, fluorescence microscopy, or structural protein modeling.  This position involves experiments with mice (~15% of time).

Please send CV, a brief statement of research interests, and names of two references to

Vladimir Y. Toshchakov, Ph.D.

Department of Microbiology & Immunology

University of Maryland School of Medicine

685 W. Baltimore Street, HSF I, Suite 380

Baltimore, MD 21201

Phone: 410-706-4716

E-mail: vtoshchakov@som.umaryland.edu

Posted: May 13, 2010

Posted: May 13, 2010

Postdoctoral Position in Virology and Cancer

A postdoctoral position is immediately available in the laboratory of Dr. Shan-Lu Liu in the Department of Molecular Microbiology and Immunology, University of Missouri, Columbia. The Liu lab is interested in retroviral pathogenesis, virus fusion and entry, as well as gene therapy using the HIV lentiviral vectors. While oncogenic sheep retroviruses associated with epithelial lung and nasal cancer in animals have been a major focus, the laboratory has recently initiated several new projects to study virus-host interactions for hepatitis C virus (HCV) that causes chronic and severe liver diseases, as well as the newly identified xenotropic MuLV-related virus (XMRV) that is associated with human prostate cancer and chronic fatigue syndrome. Highly motivated individuals with track record of productivity in virology, cell biology or cancer biology are encouraged to apply. Candidates should hold a PhD degree in the field of virology, with experiences in vesicular trafficking and confocal microscopy being particularly sought. The laboratory is located the recently established Bond Life Sciences Center at the University of Missouri, with the state-of-the-art research facility to foster innovation, interactions and productivity. Please forward cover letter, resume, and the full contact information of three references to Dr. Shan-Lu Liu via email: liushan@health.missouri.edu, Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, University of Missouri, 1201 Rollins St., Columbia, MO 65211-7310.

Posted: May 3, 2010

Posted: May 3, 2010

Dr. Terry Du Clos
Research 151, VA Medical Center
1501 San Pedro SE
Albuquerque NM 87108
Email: tduclos@unm.edu
505 265-1711 x2206
FAX: 505 256-2794

Posted: April 28, 2010

The Henry M. Jackson Foundation (HJF) is seeking a Postdoctoral Fellow for the Military HIV Research Program (MHRP) located in Rockville, Maryland. Responsibilities include

1.      Initiates and carries out HIV-1 vaccine research under the directions of Principal Investigators in the Department of Vaccine Research.

2.      Designs, develops, executes, and implements cellular immunology assays with the focus on HIV-1 vaccine development and HIV-1 pathogenesis that will lead to high impact scientific publications and that will support major grant applications.

3.      Performs specialized laboratory research utilizing cellular immunology experimental protocols which will involve some of specialized procedures such as experiments focusing on the characterization of lymphocytes from HIV-1 vaccine cohorts or HIV infected individuals. In particular: intra-cellular cytokine production, memory and activation phenotypes, NK and NKT cell phenotype and functions.

4.      Immunogenicity assays in animal models.

5.      Uses state-of-the-art flow cytometry.

6.      Molecular biology techniques.

7.      Investigates the feasibility of applying a wide variety of scientific principles and theories to the translation of basic research findings to clinical applications.

8.      Assists with the preparation of data for presentations at scientific meetings and for publication in journals.

9.      Maintains good laboratory practices under the instruction of the MHRP Principal Investigators and Laboratory Managers.

10.  Maintains cleanliness of laboratory areas.

11.  Performs other duties as assigned. 

Required Knowledge, Skills, and Abilities: Strong knowledge and hands on experience in flow-cytometry; ability to analyze and interpret data using Flowjo software; ability to draft manuscripts; ability to work as a team player in highly interactive and multi-disciplinary research environment.

Minimum Education/Training Requirements: PhD in immunology or related scientific discipline

Minimum Experience: 1-2 years of experience in immunology laboratory with focus on flow-cytometry.

Physical Capabilities: Long periods of standing and sitting; intricate work with hands; carrying of light and moderately heavy laboratory equipment

Supervisory Responsibilities/Controls: May provide guidance to research assistants and graduate and college students.

Work Environment: Laboratory environment; may involve working with biohazardous materials; may require working evenings and weekends 

Please apply on-line at www.hjf.org/careers  Click “Advanced Search” and enter job number 205233 in the Job Opening ID box. OR fax your resume to 240-314-7334. Please specify title and job number on fax.  

Posted: April 19, 2010

A ARRA-funded postdoctoral position is available immediately for a highly motivated individual in the laboratory of Dr. Kathleen Pratt at the Puget Sound Blood Center in Seattle, WA. Opportunity to work with an interdisciplinary team investigating the development of neutralizing antibodies in hemophilia A patients following therapeutic infusions of factor VIII protein.

The project involves isolation and characterization of T cells from hemophilia A blood samples, including serial samples obtained prospectively. Antigen-specific T-cell clones and polyclonal lines are generated using MHC Class II tetramers and characterized using RT-PCR, ELISAs, proliferation assays, ELiSpot, etc. Immunodominant T-cell epitopes will be identified and modified in a project aimed at designing less immunogenic versions of factor VIII targeted to specific populations. Special emphasis is placed on investigating immunologic mechanisms responsible for the greater immunogenicity of factor VIII in hemophilia A patients with black African ancestry.

Requirements: Highly motivated Ph.D., M.D., or M.D./Ph.D. with a strong background in immunology and T-cell biology. Experience with flow cytometry and RT-PCR. The successful candidate will have excellent communication skills and will enjoy working with an interdisciplinary team including immunologists, protein chemists and structural biologists.

The laboratory is part of the Puget Sound Blood Center, in Seattle, WA. The research environment includes state of the art instrumentation and access to clinical material. Interested candidates should read Ettinger RA et al., Blood 114:1423-28, 2009, and James EA et al., J. Thromb. Haemost. 5:2399-2407, 2007.

Please e-mail curriculum vitae, reprints, addresses and telephone numbers of three references to: Kathleen P. Pratt, Ph.D., kathleenp@psbcresearch.org.

Posted: April 14, 2010

Posted: April 14, 2010

POSTDOCTORAL POSITION AVAILABLE 

An NIH-funded postdoctoral position is available immediately in Suzie Pun’s laboratory at University of Washington’s Department of Bioengineering.   The project goal is to use library screening to identify new peptide markers for activated monocyte-derived cells.  These new peptides will be used in characterization of atherosclerosis lesions and for targeted delivery to specific subsets of monocyte-derived cells.   The postdoc will work in a team of researchers from the Bioengineering Department and Pathology Department at UW.   This project involves both fundamental immunology and bioengineering applications; therefore, applicants with interest in careers with translational applications are encouraged to apply.  Applicants should have a Ph.D. in immunology, microbiology, bioengineering, or related life sciences discipline with a strong publication record. 

The University of Washington is located in the beautiful Pacific Northwest and is an internationally recognized research institution.  The UW Bioengineering Department is ranked #3 in the National Research Council ranking of Bioengineering Departments.  UW offers competitive salaries and excellent benefits packages.

Interested applications should e-mail a CV, the names of 3 references and a cover letter outlining their research interests and career plans to spun@u.washington.edu. 

Suzie H. Pun, Ph.D.

Associate Professor of Bioengineering

University of Washington

Box 355061

Seattle, WA 98195 

Phone: (206) 685-3488

Fax:  (206) 543-6124

Posted: April 10, 2010

Posted: April 9, 2010

Posted: April 1, 2010

Posted: April 1, 2010

Posted: April 1, 2010

Posted: March 31, 2010

A Postdoctoral position is now available in the Wang Lab at Seattle BioMed. This project will focus on delineation of the immune mechanisms by which protective live attenuated malaria vaccines work in vivo and identification of immune signatures that reliably correlate with protection against malaria infection using systems biology approaches. Ideally, these efforts will lead to identification of a set of distinctive markers necessary to guide the rational selection of optimal vaccine antigens and the design of novel protective subunit vaccine(s) against malaria infection.

Infectious disease research is the basis for new vaccines, drugs and diagnostics that benefit those who need our help most: the 14 million people who would otherwise die each year from infectious disease. Affiliated with the University of Washington, *Seattle Biomedical Research Institute (Seattle BioMed)* is a non-profit organization founded in 1976. Our organization has grown to more than 300 staff members, and partners with key collaborators around the globe to ensure that our discoveries will save lives sooner.

What will you gain from this opportunity? You are at the right place, at the right time - Seattle is rapidly developing a reputation as an epicenter for global health research, and Seattle Biomedical Research Institute is playing a key role in the effort to eradicate global infectious diseases alongside over 100 key partnerships worldwide.

Requirements: Candidates with a Ph.D. and a strong background in cellular and molecular immunology and parasitology are encouraged to apply.

Previous experience working with small animals, plus variety of cellular assays, cell sorting and analysis by flow cytometry and microarray are highly desirable. Excellent organizational and communication and writing skills are required.

We are growing – Be involved in supporting the evolving needs of research.

Seattle BioMed is an Equal Opportunity Employer.

Apply online directly to the Seattle BioMed Job Postings webpage by clicking or typing this link:
http://www2.ultirecruit.com/sea1003/jobboard/NewCandidateExt.aspx?__JobID=321

Posted: March 30, 2010

Posted: March 30, 2010

Posted: March 29, 2010

Posted: March 23, 2010

Subjects of lab research:

Of particular interest are candidates with experience with:

But candidates will be considered from a broad range of backgrounds.

Please send resume, names of 3 references and summary of research interests to:

R. P. Junghans, Ph.D., M.D.
Director, Biotherapeutics Development Lab
Associate Professor of Surgery and Medicine
Boston University School of Medicine
Chief, Division of Surgical Research
Roger Williams Medical Center
Providence, RI 02908
Use the following email:
cdeluca0@rwmc.org

Posted: March 19, 2010

POSTDOCTORAL POSITIONS: Molecular mechanisms of allorecognition in a basal chordate

We are seeking exceptionally motivated and creative postdoctoral fellows to investigate the mechanisms of allorecognition in the basal chordate, Botryllus schlosseri. This is an innate system which appears to be analogous to the missing-self recognition found in mammalian NK cells. We have recently identified both ligands and a receptor family involved in this reaction, and projects include: 1) dissecting the reaction in vivo using mAb interference and siRNA-mediated reverse genetics; 2) exploring how specificity is achieved, including mechanisms of education during embryogenesis and maintenance during regeneration; 3) in vivo and ex vivo direct binding assays. 

Applicants should hold or be near completion of their PhD in immunology, cell biology or a related field. Experience in flow cytometry, microscopy, tissue culture and histology is a plus, and you should not be afraid to get your hands wet.

Qualified applicants should email a single PDF file with a cover letter, statement of research interests, CV and contact information for three references to: detomaso@lifesci.ucsb.edu.

Dr. Tony De Tomaso
Molecular, Cellular and Developmental Biology
UC Santa Barbara
Santa Barbara, CA 93106

Posted: March 18, 2010

The NIH is dedicated to building a diverse community in its training and employment programs.

Posted: March 18, 2010

Department of Health and Human Services
National Institutes of Health
National Institute of Allergy and Infectious Diseases

Postdoctoral Fellow—Pathogenesis of HIV Infection 

The National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research (DIR), Laboratory of Immunoregulation (LIR), HIV-Specific Immunity Section (HSIS) is seeking an outstanding postdoctoral fellow to participate in basic and clinical research in the pathogenesis of HIV infection. 

DIR’s mission is to design, initiate, and conduct important basic science and clinical investigations in cutting-edge areas of infectious diseases and allergy/immunology, particularly those of major public health importance. The scientific research program of HSIS is focused on investigating humoral immunity in HIV infection.  

There is a growing consensus that effective vaccines for HIV will require a humoral response capable of recognizing diverse isolates. The laboratory has recruited a cohort of patients with a broad and potent neutralizing antibody response to HIV. Sera and cells from these patients are being used in state-of-the-art assays for neutralization, sorting, and single-cell expansion of antigen-specific B cells and for cloning and expression of immunoglobulin genes to better understand the basis of the neutralizing antibody response to HIV.  

Applicants should have a Ph.D. and/or M.D. Experience in measuring humoral immune responses in humans or animals and basic molecular biology techniques is desirable. Salary range is commensurate with experience. 

Interested candidates may contact Mark Connors, M.D., at mconnors@niaid.nih.gov for additional information about the position. To apply, candidates must submit a curriculum vitae, a bibliography, three letters of reference, a detailed statement of clinical research interests, and reprints of up to three selected publications to National Institute of Allergy and Infectious Diseases, Division of Intramural Research, c/o LIR Office of the Chief, Attn: Dr. Marybeth Daucher (mdaucher@niaid.nih.gov), 10 Center Drive, Room 6A19, Bethesda, MD 20892-1884 by May 31, 2010. 

For further information about NIAID and available job opportunities, visit www.niaid.nih.gov/careers/phi4.

HHS, NIH, and NIAID are proud to be Equal Opportunity Employers.

Posted: March 12, 2010

Posted: March 9, 2010

Independence and a high degree of self-motivation are encouraged in the laboratory, as is the ability to work with others. Candidates must have a Ph.D. or comparable degree in Molecular Biology, Immunology, Biochemistry, Pharmacology, or a related field. A background in immunology/B cell development and/or reproductive hormones would also be useful, as would knowledge of molecular and cellular biologic techniques, flow cytometry, and work with animals. This position is funded by the NIH and is available immediately.

Please send CV and the names of several references to Ruth.W.Craig@Dartmouth.edu
or
Dr. Ruth W. Craig
Department of Pharmacology and Toxicology Dartmouth Medical School Hanover, NH 03755
Telephone: 603 650-1657
Fax: 603 650-1129

Posted: March 8, 2010

Posted: March 8, 2010

Posted: March 8, 2010

Posted: March 5, 2010

A postdoctoral position is available immediately to study the pathogenesis of SIV infection in Rhesus macaques, with particular emphasis on the biology of SIV mucosal transmission and immunological impact of virus adaptation to new hosts. The candidate should have a PhD/MD degree and be familiar with basic techniques in molecular virology, cell biology and immunology. Research experience in SIV/HIV virology, innate immunology, SIV pathogenesis is highly desirable. Individuals with experience working with nonhuman primates are particularly encouraged to apply. Candidates must be authorized to work in the United States. The Center for Vaccine Research is housed in a state-of-art facility that has research programs focusing on AIDS and emerging infectious diseases and is part of a larger research community at the University of Pittsburgh that currently ranks sixth nationally in NIH funding. Interested individuals should submit a letter of application, curriculum vitae, and their name, address, e-mail and telephone number for three references to Cristian Apetrei, Center for Vaccine Research, University of Pittsburgh, 9044 BST3, 3501 Fifth Avenue, Pittsburgh, PA 15261. Tel: 412-624-3235. E-mail: apetreic@pitt.edu.

· E-mail preferred method of contact.
· Website: www.cvr.pitt.edu

The University of Pittsburgh is an equal opportunity, affirmative action employer. Women and minority candidates are strongly encouraged to apply.

Posted: March 4, 2010

Post-doctoral position in mast cell signaling and inflammation

A post-doctoral fellow position in mast cell signaling and inflammation is available in the laboratory of Andrew Craig at Queen’s University in Kingston, Ontario.  The starting date is April 1, 2010, with an expected term of 3-4 years.

My lab is studying the molecular mechanisms governing mast cell activation and mediator release.  We employ transgenic mouse models and cell-based models to define the functions of proteins involved in phosphotyrosine-based signaling mechanisms in mast cells ( http://qcri.queensu.ca/Craig.html). 

For this project, the PDF will define the roles of F-BAR domain-containing proteins in mast cell activation.  We have characterized the contributions of the F-BAR domain in membrane targeting and activation of FER protein-tyrosine kinase recently (McPherson et al. (2009) MCB 29:389-401), and plan to extend this work to a number of F-BAR-containing adaptor proteins that have not been previously studied in mast cells.

The applicant should be a highly motivated, recent Ph.D. graduate with expertise in molecular and cell biology, and excellent communication skill in English.  Experience working with transgenic mice would be considered an asset.

Applicants should submit a CV with their publications and contact information for 2-3 referees via email to Dr. Andrew Craig (ac15@queensu.ca). 

Posted: March 4, 2010

Postdoctoral position is available in the Unniraman lab in the Department of Immunology at Duke University Medical Center (Durham, NC) to study the mechanism of affinity maturation of antibodies by somatic hypermutation and class switch recombination.  We use cell-line-based genetic screens to identify factors that target these mutagenic reactions to the antibody genes while ensuring the protection of the rest of the genome.  You can get more details of our work at https://faculty.duhs.duke.edu/faculty/info?pid=29730. 

An ideal applicant would be highly motivated with strong analytical skills.  A strong background in molecular biology is required.  Experience in BAC transgenics or library-based genetic screening is highly desirable.   Start dates are flexible. 

Applicants should email their CV and a summary of their research experience to Shyam Unniraman: shyam.unniraman@duke.edu.

Dr. Shyam Unniraman
Email: shyam.unniraman@duke.edu
Address:Edwin L. Jones Bldg, Rm 312
Campus Box 3010
Dept of Immunology
Duke University School of Medicine
Durham, NC  27710
Phone: (919) 660-9003
FAX: (919) 684-8992

Posted: March 4, 2010

The CVD offers a unique environment to study cellular and molecular determinants of protection to infectious diseases in humans. The CVD, largely supported by NIH funding and private foundations, has earned an international reputation for genetically engineering and testing vaccines against typhoid, shigella, cholera and malaria. Based at the School of Medicine, University of Maryland, Baltimore, the CVD was established in the mid-1970s as one of the first facilities to evaluate vaccines in community volunteers. It is one of only a handful of vaccine centers in the world engaged in the full range of vaccinology - from basic science through vaccine development, immunological studies, clinical evaluation and field studies.

The successful candidate should have a Ph.D. in Microbiology/Immunology or M.D. degree, experience in the study of immunological mechanisms, a strong publication track record, be highly motivated, have effective written and oral communication skills and hold a valid VISA to work in the US. Experience in flow cytometry and other CMI techniques, as well as molecular biology, functional genomics and/or tetramer technologies is highly desirable. Please send curriculum vitae, a brief outline of relevant research experience and interests and the names of three references via e-mail to Marcelo B. Sztein, M.D., Professor of Pediatrics; Leader, CVD Immunology Group; Chief, Cellular Immunology Section and Flow Cytometry Core Laboratory; CVD; University of Maryland at msztein@medicine.umaryland.edu. Further information about the CVD can be found at: http://medschool.umaryland.edu/CVD/. The UM is an affirmative action/equal opportunity employer.

Posted: March 4, 2010

Posted: March 4, 2010

Posted: March 4, 2010

This is a 3-year grant funded fellowship. In this integral role, the Postdoctoral Fellow will work under the general supervision of the Radiation Immune Research Director and other investigators to study the effects of neo-adjuvant hormone therapy and radiation therapy
on tumour-specific immune responses in prostate cancer. The project will involve use of mouse models, as well as a prospective cohort of prostate cancer patients who have participated in clinical and immunological monitoring since 2004. The overarching goal is to understand how treatment-induced antibody and T cells responses influence clinical outcomes in prostate cancer, and how best to enhance these responses therapeutically.

In addition to two years of related experience in experimental animal handling, a Ph.D in a related discipline such as Immunology, Biology, Microbiology, or Biochemistry is required. The successful candidate will have skills and experience in mammalian cell culture, general molecular biology techniques, immunoassays (cytokine, and cytotoxicity assays), flow cytometry, T cell biology and cell signalling pathways. An equivalent combination of education, training and experience will also be considered. The Postdoctoral Fellow will be able to work independently, and demonstrate excellence in conception, development and execution of a research project. Strong skills in scientific writing (grants, manuscripts) and oral presentation are required and the incumbent is expected to successfully attract funding during the fellowship. In addition, the successful candidate must be detail oriented, motivated and desire to work in a translational research environment

For more information about our centre, please visit: http://www.bccrc.ca/drc/. Applications can be submitted via email to:

Dr. Julian J. Lum
Deeley Research Centre. BC Cancer Agency-Vancouver Island Centre
2410 Lee Avenue
Victoria, BC, Canada; V8R 6V5
Email: jjlum@bccancer.bc.ca

Posted: March 4, 2010

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Updated 09/02/10