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A postdoctoral position is immediately available to study stimulation of the immune system in peripheral and mucosal sites by bacterial toxins. The goal of this project is to uncover points of intersection between the innate and adaptive immune systems. Experience using in vivo models and interest in the study of inflammatory processes is desirable.

Potential candidates should possess a Ph.D., have strong writing skills, and solid training in the biological sciences. If seriously interested please send your CV, brief description of your research experience, and the contact information of three references in a pdf document to vella@uchc.edu.

Anthony T. Vella, Ph.D.
Associate Professor
Department of Immunology-MC1319
University of Connecticut Heath Center
263 Farmington Avenue
Farmington, CT 06030
Fax: (860) 679-1868
email: vella@uchc.edu 

UCHC is an equal opportunity employer M/F/V/PwD.

Posted: July 2, 2009


Postdoctoral Fellow
Department of Medicine, GI Division and Center for Infectious Diseases and Translational Microbiology


Three post-doctoral positions are available for studies on the immune response to typhoid. Studies will involve the examination of innate and adaptive immune responses to Salmonella using in vitro and in vivo techniques. A Ph.D. in medical sciences, training in Immunology, and knowledge of the biomedical literature, and experience with immunological assays are required.

Minimum Qualifications – Knowledge Skills and Abilities: Must possess a Ph.D. in medical sciences and have training in immunology and infectious diseases. Must have several years experience using in vitro and/or in vivo immunology assays. Must be able to learn new techniques and keep careful records. Must be adept at handling and manipulating mice for in vivo immunology experiments.

Preferred Experience and Training: Experience in flow cytometry, confocal microscopy, and examining immunity to pathogens is preferred.

Interested applicants should email a complete CV to mcsor002@umn.edu.

Stephen J. McSorley, Ph.D.
Associate Professor,
University of Minnesota,
CIDMTR,
McGuire Translational Research Facility,
TRF DC 2873,
2001 6th Street SE,
Minneapolis, MN 55455
Tel: 612-626-9905

Microbiology, Immunology & Cancer Biology (MICaB) Ph.D. Graduate Program: http://www.micab.org

Posted: July 1, 2009


A postdoctoral position is available immediately in the laboratory of Dr. Dorina Avram in the Center for Cell Biology and Cancer Research at Albany Medical College, Albany, NY, to study the role of the transcription factor BCL11B in T cell development and leukemia. This project will utilize conditional knockout and transgenic mouse models, as well as some in vitro experiments (Albu et al., 2007. J. Exp. Med. 204: 3003-3015; Cismasiu et al., 2006. Blood. 108:2695-2702). The successful candidate will join a well-funded laboratory with two other postdoctoral fellows, two graduate students, four medical students and two technicians. The laboratory has access to a flow cytometry facility with an Aria cell sorter and a 6 color FACSCanto flow cytometer and, in addition, the lab has its own 5 color FACSCalibur flow cytometer with permanent access. The successful candidate will have the opportunity to interact with investigators, postdoctoral fellows and graduate students of the Center for Cell Biology and Cancer Research, as well as of the Center for Immunology and Infectious Disease. A PhD in Immunology is preferred or at least good understanding of basic immunology is necessary. Experience with mouse models and flow cytometry is required.

Salary will be commensurate with experience in accordance with the NIH guidelines. If interested, please send by email a CV, addresses of three references, and a letter specifically describing your interests and goals to AvramD@mail.amc.edu.

Dorina Avram, Ph.D.
Associate Professor
Center for Cell Biology and Cancer Research Albany Medical College
47 New Scotland Avenue (MC 165)
Albany, NY 12208
Tel: 518-262-6731
Fax: 518-262-5669
email: avramd@mail.amc.edu

Posted: June 30, 2009


Dr. Richard Junghans, Chief of Surgical Research at Roger Williams and principal investigator on a $5.9 million breast cancer grant, is at the forefront of research that aims to redirect the immune systems of cancer patients to fight their cancers. This is done by using gene therapy techniques to modify the patients' own T cells to create "designer T cells." As part of the research, a coordinated series of clinical trials and laboratory research activities is planned with the focus of curing metastatic breast cancers via this emerging technology.

In this position you will develop and apply designer T-Cells in Cancer and infectious disease.

Education: MD, Ph.D, or MD, PhD in cellular biology, molecular biology, or related field.

Experience: Experience in immunotherapy, molecular biology, or gene therapy and animal models. Experience in transcription factors or Tcell signaling a plus.

For consideration please submit curriculum vitae and the names and contact information (address, telephone number and e-mail address) for 3 individuals qualified to comment on the applicant’s research and academic skills via email to ejuckett @rwmc.org. (Preferable method of acceptance)

Contact Information:

Liz Juckett * Human Resource Generalist * Roger Williams Medical Center * 825 Chalkstone Ave * Providence, RI 02908

Posted: June 29, 2009


Postdoctoral Position at the University of Iowa
Adaptive CD8 T cell responses

NIH supported postdoctoral position is immediately available to investigate the role of repeated antigen stimulations on antigen-specific CD8 T cell responses. For background information please see: Nat Rev Immunol 8:107, 2008; Immunity 26:827, 2007; Immunity 25:19, 2006.

Qualifications: Interested candidates must be highly motivated, have a PhD in immunology, and a good record of publications in peer-reviewed English journals. Excellent written and oral communication skills required. Ideal candidates will have demonstrated experience of mouse models of infections, and flow cytometry.

Please send curriculum vitae, a short description of research experience, and names and contact information of three references to:

Vladimir Badovinac, Ph.D.
Asst. Professor
University of Iowa
Department of Pathology
137 MRC
Iowa City, IA 52246
vladimir-badovinac@uiowa.edu
http://www.healthcare.uiowa.edu/pathology/site/faculty/badovinac/badovinac.html

Posted: June 29, 2009


Postdoctoral Position in Immunology
E mail:  mullenh@health.missouri.edu
Phone: 573-882-7150; Fax 573-882-1380

Postdoctoral positions are available to participate in an NIH funded research project in the laboratory of Dr. Helen Braley-Mullen at the University of Missouri. The project uses a murine model of autoimmune thyroid disease in which NOD.H-2h4 mice lacking IFNgamma develop very severe hyperplasia of thyrocytes and fibrosis. The main focus of the work is to understand the cellular and molecular mechanisms by which CD8+ T cells and cytokines function to promote development of the severe thyrocyte hyperplasia and fibrosis. Applicants must have recently completed a Ph.D and/or M.D. in Immunology or a closely related area, and have research experience in cellular immunology and/or molecular biology. Another project focuses on understanding the mechanisms by which B cells regulate development and progression of autoimmune diseases using a mouse model of thyroiditis.  Depending on background and interests, it would be possible for a candidate to divide their time and participate in both projects. Interested individuals should send a copy of their c.v., a summary of research interests and names of 2 or 3 individuals (with their e mail addresses) who could be contacted for letters of reference.  The preferred means for contact is e mail. The University of Missouri is an equal opportunity employer.

Posted: June 29, 2009


Postdoc in Cancer Immunology

A postdoctoral research position in Cancer Immunology is open in the Division of Biological Sciences at the University of Chicago, Chicago, IL USA. Our lab is part of an active group of researchers in the field of transplant and tumor immunology. The postdoctoral fellow will have access to state-of-the art technologies and core facilities, including optical and multiphoton imaging, multicolor flow cytometry, antibody production, genomics including microRNA arrays, and a transgenic/knockout facility. In addition, there is an Immune Monitoring core and a GMP facility for potential translational work.

Our lab is interested in studying the regulatory pathways for tumor evasion and genesis, particularly focusing on a subset of the TNF receptor family and the role of regulatory T cells in this setting. Particularly, we are studying signaling pathway(s) that link Treg and the innate immune cellular components which mediate tumor immunity and tolerance, and the impact of Treg migration and localization in mediating inflammation and tumor growth.

The long-term goals are to develop novel therapeutic targets and engineer cellular therapy in the field of stem cell transplantation. The position is intended for exceptional candidates with an M.D., Ph.D., or M.D/Ph.D., who has excellent graduate training and a record of publications in immunology/molecular biology/cancer biology. Experience in innate immunity and T-cell biology, molecular biology, cancer models, optical or multiphoton imaging, and in vivo mouse models is highly desired.

The position is available immediately. Interested applicants should email their curriculum vitae, a statement of current and future research interests, and complete contact information of three references. The applicant must be able to come to Chicago for an interview if invited (Please do not respond if you're not able to travel to present your research).

For more information on our program, please visit: http://www.bsd.uchicago.edu.

Dr. Vu Nguyen
Division of Biological Sciences
University of Chicago
vnguyen@medicine.bsd.uchicago.edu

Posted: June 29, 2009


Postdoctoral Position at the Ragon Institute of MGH, MIT and Harvard
HIV antigen processing and immunity
 

A postdoctoral position is currently available in the laboratory of Dr Sylvie Le Gall at the Ragon Institute of MGH, MIT and Harvard in Boston. The group is interested in deciphering the mechanisms of HIV protein degradation and their contribution to the specificity and antiviral potential of anti-HIV immune responses. The group is part of a team-oriented Institute aiming at understanding correlates of HIV immune protection through multi-disciplinary approaches.   

Requirements:

  • Recent Ph.D. or M.D/Ph.D. with strong background in immunology and/or biochemistry, cell biology or virology
  • Solid technical experience in protein biochemistry and/or cellular/molecular immunology
  • Good record of publications in peer-reviewed English
  • Excellent written and oral communication skills in English
  • Excellent organization, writing and data analysis skills\
  • Able to write lab reports and drafts of manuscripts
  • Highly motivated, team-oriented

Salary will be commensurate with experience in accordance with the NIH scale.

Qualified candidates can send a cover letter and C.V. (including a list of publications, research experience, and a statement of current/future research interests), and contact information for three references by email to sylvie_legall@hms.harvard.edu 

Sylvie Le Gall, Ph.D., Assistant Professor of Medicine, Ragon Institute of MGH, MIT and Harvard, CNY149 13th Street, Rm. 5220, Boston MA 02129

Posted: June 29, 2009


Postdoctoral position in immunology. Lyon, France

A post-doctoral position funded by the FINOVI foundation for two to four years is available at the INSERM U851 unit in Lyon, France. Our lab is interested in the differentiation and migration of Natural Killer cells and cytotoxic T cells. We previously identified several genes that were specifically expressed in cytotoxic lymphocytes in both mouse and human, including G-protein coupled receptors. We will study the importance of the identified pathways and genes using a number of approaches including existing knockout and transgenic mice and blocking or stimulatory reagents that can be used in vivo (e.g. antibodies) or in vitro. This position will be open in September 2009 and offers a competitive salary (in the range of 2150 euros per month).

For more information and to apply for this position, please contact Thierry Walzer: thierrywalzer@gmail.com. Please include a cover letter addressing your interest in the position along with your resume, summary of your research experience and contact information of two professional references.

Relevant publications:

1. Chiossone L, Fuseri N, Chaix J, Roth C, Vivier E and Walzer T. Maturation of mouse NK cells is a four-stage developmental program that balances proliferation with effector functions. (2009) Blood, In press

2. Chaix J, MS Tessmer, K Hoebe, N Fuséri, B Ryffel, M Dalod, L Alexopoulou, B Beutler, L Brossay, E Vivier and Walzer T. Priming of Natural Killer cells by Interleukin-18. Cutting Edge: Journal of Immunology (2008). 181(3):1627-31

3. Walzer T, Chiossone L, Chaix J, Calver A, Carozzo C, Garrigue-Antar L, Jacques Y, Baratin M, Tomasello E, Vivier E. Natural killer cell trafficking in vivo requires a dedicated sphingosine1-phosphate receptor. Nature Immunology. (2007) Dec; 8(12):1337-44.

4. Walzer T, Blery M, Chaix J, Fuseri N, Chasson L, Robbins SH, Jaeger S, Andre P, Gauthier L, Chemin K, Dalod M, Imbert J, Pierres M, Moretta A, Romagne F, Vivier E. Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. Proceedings of the National Academy of Sciences U S A. (2007) Feb 27;104(9):3384-9.

Posted: June 29, 2009


A postdoctoral position at the City of Hope 

A highly motivated postdoctoral research fellow in cellular immunology is wanted to study the signaling molecules involved in T cell activation and differentiation. Experimental approaches require the candidate to be familiar with immunology knowledge as well as techniques such as flow cytometry, Th1/Th2/Th7 differentiation, and animal model. Experience with retrovirus and autoimmune disease models such as EAE is a plus. Candidate shall have publication records to demonstrate the experience in the research area. The postdoctoral scientists will have considerable freedom to develop related research projects according to his/her interests. Our lab is located in Immunology Division of the Beckman Research Institute of the City of Hope. The institute and department have state-of-the-art facilities and resources to carry out cutting-edge research. See our lab website for more information: http://www.cityofhope.org/directory/people/sun-zuoming/Pages/default.aspx. Please send your application materials such as CV, publications, and references to: zsun@coh.org.

Posted: June 29, 2009


Postdoctoral Position at Vanderbilt University
Tolerance and autoimmunity to Goodpasture autoantigen

A postdoctoral position is immediately available in the laboratory of Dr. Dorin Bogdan Borza at Vanderbilt University. The lab studies how immune tolerance toward type IV collagen is normally established in health, broken in autoimmune Goodpasture disease, and impaired in alloimmune Alport post-transplant nephritis. This position will investigate the specificity of cellular and humoral adaptive immune responses against GBM-specific isoforms of type IV collagen in antigen-sufficient and -deficient mice, and also characterize novel types of pathogenic auto- and allo-antibodies from patients with anti-GBM disease.

Qualifications: Interested candidates must have a pending or recent Ph.D. degree with a strong background in immunology or a related discipline, and a good record of publications in peer-reviewed English journals. Excellent written and oral communication skills English are important. The successful candidate will be highly motivated, able to work independently and to handle multiple projects concurrently. Prior experience with mouse models of autoimmunity or inflammation, characterization of adaptive cellular immune responses, or kidney immunopathology is desirable. Salary will be commensurate with the relevant experience, and an excellent benefits package is included (http://bret.mc.vanderbilt.edu/postdoc/html/benefits.php). One of the top 20 research medical schools in the US, Vanderbilt University ranks among the “Best Places for Postdocs” and "Best Places to Work in Academia" (The Scientist, 2008). The University is located in Nashville, Tennessee, which ranks among the best 15 U.S. cities for work and family (Fortune Magazine).

To apply, please send your C.V. (including a list of publications, research experience, and a statement of current/future research interests), and contact information for three references by email to Dorin-Bogdan.Borza@vanderbilt.edu.

Posted: June 19, 2009


Post-doctoral positions in mucosal immunology

Two (2) NIH supported postdoctoral positions are available immediately to investigate the role of cytokines in the regulation of CD8 T cell responses at mucosal surfaces. The research projects include both in vivo and in vitro studies focused on the cellular and molecular interactions of respiratory or intestinal epithelial cells and DCs with CD8 T cells and how the spatial and temporal cytokine milieu ultimately influences memory CD8 T cell development, trafficking, and maintenance.

Candidates must be highly motivated, have a Ph.D. in a relevant field of study, a strong publication record, and the ability to multi-task and work independently. Ideal candidates will have demonstrated extensive knowledge in immunology and have experience with mouse models, animal tissue collection, lymphocyte isolation, standard tissue culture techniques, and flow cytometry. Excellent written and oral communication skills in English are also essential.

Our laboratory is located in the newly designed state-of-the-art Coverdell Building for Biomedical Research in Athens, GA which is located 61 miles from downtown Atlanta. This year Athens was Kiplinger’s choice for the no. 5 Best City in the US.

For consideration please submit a CV including the names and contact information for 3 qualified references as well as a 1 page description of your research experience and interests (preferably by e-mail) to:

Dr. Kim Klonowski
Asst. Professor
University of Georgia
Dept. of Cellular Biology
Room 330A Coverdell Building
Athens, GA 30602
klonowski@cb.uga.edu
http://www.uga.edu/cellbio/klonowski.html

Posted: June 19, 2009


Postdoctoral Position in Immunology/Development at the University of Chicago

A postdoctoral position is available in my laboratory to investigate the molecular mechanisms controlling lymphocyte development. For background information see Kee Nat. Rev. Immunol. 9:175, 2009; Dias et al. Immunity 29:217, 2008; Boos et al. J. Exp. Med. 204:1119, 2007. Applicants should have a Ph.D. and significant experience in molecular biology as applied to gene expression and analysis, animal care and flow cytometry.

Interested applicants should send their CV and the names/email addresses for 3 referees to Dr. Barbara L. Kee.

Posted: June 19, 2009


Postdoctoral Position: Structure / Function Analysis of MHC Class II Molecules

A postdoctoral training position is available in the laboratories of Drs. Jim Drake and Jonathan Harton in the Center for Immunology and Microbial Disease at Albany Medical College.

This is an opportunity for a highly motivated and well-trained postdoctoral fellow to become an integral part of a research project designed to establish the impact of MHC class II structure on class II function. The project is the direct extension of work published in The Journal of Immunology (Nashar and Drake, 2006, JI 176: 827).

Salary will be commensurate with experience in accordance with the NIH scale.

Requirements:

  • Ph.D. in the areas of immunology, cell biology and/or molecular biology
  • Peer-reviewed publications in the applicant’s field of training
  • Strong technical background in the areas of molecular biology, cell biology and/or molecular immunology
  • Excellent communication skills in both written and spoken English

Applicants should send a cover letter, statement of research interests, CV and list of 3 references (including their present research supervisor) to:

Jim Drake, Ph.D., Professor, Albany Medical College, Center for Immunology and Microbial Disease, 47 New Scotland Ave., MC-151, Albany, NY 12208-3479 -- drakej@mail.amc.edu.

Posted: June 19, 2009


Postdoctoral Associate in viral immunity and pregnancy, effective immediately
University of Vermont College of Medicine
Department of Obstetrics, Gynecology and Reproductive Sciences

Join the ethnically diverse and enthusiastic laboratory of Dr. Elizabeth Bonney to address the complex issue of maternal immunity as it relates to viral infection. Specific interests include host cell-virus interaction, T cell function, and placental biology.

The candidate must have a Ph.D. in a related field and at minimum have working knowledge and experience in virology, immunology and mouse models. Excellent written and oral communication skills are also essential. An ability to take on leadership or administrative responsibilities is highly desirable.

Please send curriculum vitae, three references and a statement of research interests via email to: ebonney@uvm.edu.

U.S. citizens who are women or who are members of an underrepresented minority group are strongly encouraged to apply.

Posted: June 16, 2009


Postdoctoral Fellow

The Department of Pharmacology seeks outstanding candidates for three (3) full-time positions as a Postdoctoral Fellows in the University of Missouri-Kansas City (UMKC) School of Pharmacy. The successful candidates will be involved in an ongoing research program focused on the neuropathogenesis of HIV-1 with particular emphasis on the effects of drug abuse on neuroAIDS. The research program utilizes both cell culture models and the SHIV-SIV/macaque model of AIDS to study the combined effects of drugs of abuse on HIV-1 infection in terms of virology, immunology and neurology.

Candidates must have an earned doctoral degree in an aspect of biomedical research with a publication record of original research in peer-reviewed journals. Candidates must have the ability to work independently as well as the ability to collaborate with others within the group. Research experience in virology, molecular biology, immunology or neurology is preferred.

For consideration please submit curriculum vitae and the names and contact information (address, telephone number and e-mail address) for 3 individuals qualified to comment on the applicant’s research and academic skills. Materials should be sent, preferably by e-mail, to:

Dr. Anil Kumar, Division of Pharmacology and Toxicology, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, kumaran@umkc.edu.

Posted: June 16, 2009


Postdoctoral Position: Host Defense and Immunity to Infection

A postdoctoral position is available immediately to investigate the mechanisms of host resistance against an intracellular protozoan parasite, Toxoplasma gondii, using murine models. The projects include studies of interactions between innate immune cells and T cells in host defense and vaccine development. Individuals with a Ph.D. and a strong background in immunology and cellular/molecular biology are desirable.

Send curriculum vitae, a short description of research experience and interest, and names and addresses of three references to: Yasuhiro Suzuki, Ph.D., Professor, Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, 800 Rose Street, Lexington, KY 40536. E-mail: yasu.suzuki@uky.edu.

Posted: June 16, 2009


Postdoctoral Position Available
Principal Investigator: Samita Andreansky
Assistant Professor, Sylvester Cancer Center, University of Miami Miller School of Medicine

A postdoctoral position is currently available for qualified candidates to design and develop new immunotherapies and immunologic strategies for malignancy and virus infections. Special emphasis are given on how negative immunoregulatory mechanisms impact vaccination strategies. Applicants should have Ph.D. or M.D, or equivalent. Experiences in virology, mouse models and flowcytometry are highly desirable with a strong ability to work in a cross-disciplinary environment.

Send resume and one page of research interests to sandreansky@med.miami.edu.

Posted: June 12, 2009


Postdoctoral Position: Host-Pathogen Interactions

A postdoctoral research position is available in the laboratory of Dr. Liselotte E. Jensen in the Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, USA. http://www.med.upenn.edu/pharm/faculty/jensen/jensen.html.

The highly motivated successful applicant will study the role of Toll-like receptors, inflammasomes and cytokines during Staphylococcus aureus infections of the skin. Additional pathogens may be studied. Experimental models will include in vitro assays, tissue culture and mouse models. The study aims to identify novel regulators of signal transduction.

Requirements:

• A Ph.D. in Immunology, Microbiology and/or Molecular Biology.
• Peer-reviewed publications in the field(s) of Immunology, Microbiology and/or Signal Transduction.
• Experience with molecular biology, biochemistry, immunology, histology, signal transduction and cell culture methods.
• Excellent written and oral communication skills in English.

Additional experience with animal handling (mice) and breeding, inflammatory models (especially skin and mucous membranes) and/or vaccine development is highly desirable.

Send cover letter, statement of research interests, CV and contact information for 3 references to:

Liselotte E. Jensen, Ph.D., Department of Pharmacology, University of Pennsylvania, 89 John Morgan Building, 3620 Hamilton Walk, Philadelphia, PA 19104-6084; E-mail: liselott@mail.med.upenn.edu

Posted: June 12, 2009


Postdoctoral Position: Innate Immunity and Liver Inflammation

A postdoctoral position is available immediately in the laboratory of Dr. Liselotte E. Jensen in the Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, USA. http://www.med.upenn.edu/pharm/faculty/jensen/jensen.html.

The successful candidate will be highly motivated to study innate immune responses during viral infections and chronic inflammation of the liver. Signaling pathways activated by Toll-like receptors and cytokines will be explored. Experimental models will include in vitro assays, microarray screening, tissue culture and a novel knockout mouse strain.

Requirements:

• A Ph.D. in Immunology, Cell Biology and/or Molecular Biology.
• Peer-reviewed publications in the field(s) of Immunology, Liver Physiology/Pathology and/or Signal Transduction.
• Hands-on practice with animal handling (mice) and breeding.
• Extensive experience with molecular biology, biochemistry, immunology, histology, signal transduction and cell culture methods.
• Excellent written and oral communication skills in English.

Additional experience with in vivo models of liver inflammation is an advantage.

Send cover letter, statement of research interests, CV and contact information for 3 references to:
Liselotte E. Jensen, Ph.D., Department of Pharmacology, University of Pennsylvania, 89 John Morgan Building, 3620 Hamilton Walk, Philadelphia, PA 19104-6084; E-mail: liselott@mail.med.upenn.edu

Posted: June 12, 2009


Postdoctoral Fellow, Immunology
Job Code: JD05-027

A postdoctoral position is open in my group for a candidate who will pursue research in the areas of innate immunity and immune signaling, with an emphasis on understanding how adaptive immunity is instructed and modulated by the innate response.  The successful candidate will have training and expertise in innate immunity, in vitro modeling of immune function, immune signaling or a related field of immunology. The candidate will be expected to design and implement experiments and explore new biology in the areas of innate cell function and signaling, as well as understanding its application to disease research. Knowledge of techniques such as flow cytometry, cell sorting, DNA/RNA/protein analysis, and in vivo modeling of immune function is also highly desirable.  The position requires a minimum of a Ph.D. in a relevant field of study, and a successful publication record.  Excellent communication, organization, writing and data analysis skills are also a must, as well as a positive outlook and a team-oriented attitude.

Interested candidates please send a copy of your CV including publication record, and three references to jobs@gnf.org. Website: www.gnf.org.

Posted: June 9, 2009


Postdoctoral Fellowship at Stanford University School of Medicine

Post-doctoral position available immediately to study immune and viral mechanisms in the growth and survival of Epstein Barr virus
(EBV) B cell lymphomas. The specific areas of focus are the signal transduction pathways initiated by the EBV protein latent membrane
protein 1 that contribute to host cell survival. For more information please check recent publications (J Biol Chem 283:36573, 2008; J Immunol 179:8225, 2007; J Immunol 177:3283, 2006).

The successful candidate will be highly motivated and have a Ph.D. in Immunology, Virology or Molecular Biology with a strong record of peer-reviewed publications and experience in immunology, virology or tumor biology. Experience in cell culture, flow cytometry, cloning and basic immunologic, biochemical, and molecular techniques is required. Fluency in English and strong written and oral communication skills are essential.

Interested applicants should send CV, statement of research interests and three letters of reference to:

Olivia Martinez, Ph.D.
Professor
Stanford University School of Medicine
1201 Welch Road, MSLS P312
Stanford, CA 94305-5492
EMAIL: omm@sanford.edu

Posted: June 1, 2009


Research positions at Northwestern University

NIH funded postdoctoral research positions are available immediately. Requirements include a Ph.D and/or M.D. in immunology or other cell biological field with an outstanding publication record. We are particularly looking for candidates with strong research background in cellular immunology and autoimmune diseases, such as type 1 diabetes and rheumatoid arthritis, using mice as animal models. Ph.D students graduated within two years are particularly encouraged to apply.

The focuses of our research are the molecular mechanisms of the development, activation, differentiation and tolerance of both T- and B-lymphocytes, as well as the development of autoimmune diseases. Current ongoing research projects are 1) epigenetics in immune regulations, 2) microRNA in T-cell activation and tolerance, and in autoimmune disease development, 3) ubiquitination and autoimmunity and 4) T-cell signal transduction and the allergic lung inflammation.

Please send your resume and names of three references of your current and previous mentors to:

Deyu Fang, Ph.D., Associate Professor, Department of Pathology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611-3008, E-mail: fangd@northwestern.edu

Northwestern University is an affirmative action/equal opportunity employer.

Posted: May 28, 2009


A postdoctoral position is available immediately to study cell signaling in the immune system using autoimmunity, allergy and cancer models. For more information see Venuprasad K et al. Nat Immunol. 2008; 9(3):245-53, Venuprasad K et al. J Clin Invest. 2006.116(4):1117-26, Chang L et al. Cell. 2006; 124(3):601-13, Jeon MS et al. Immunity. 2004 21(2):167-77. The applicant should have completed a Ph.D. and/or M.D. in Immunology, Biochemistry, or Molecular Biology, The ideal candidate will have successful research experience in molecular biology, bio-chemistry and/or immunology. The successful candidate will be joining a very stimulating environment within the Karmanos Cancer Institute and the Dept. of Microbiology and Immunology at the Wayne State University.

If interested, please send a CV and contact information of 2-3 references to Dr. Venuprasad K. Poojary at poojaryv@karmanos.org.

Posted: May 28, 2009


A NSERC-funded Ph.D. studentship is available to work on an anti-bacterial antibody that in and of itself causes specific target cell death.

Our preliminary data suggest that this antibody has coevolved two functions onto one molecule: specific binding to the surface of a pathogen, and the ability to kill it. We have demonstrated these phenomena with the IgG as well as with its Fab and scFv fragments. Also, antibody treatments cause cell wall disruptions in bacterial targets, as seen by electron micrographs, and protected a neutropenic mouse model from death after LD90 administration of specific bacteria.

The successful candidate will work towards discovering the mechanism that is involved in this specific antibody-mediated bacterial cytotoxicity through biochemical, structural and immunological research. Experience with or sound knowledge of these technologies will be required.

It is anticipated that research outcomes will result in understanding a novel mechanism of cytotoxicity with potential for the development of applications in medicine and health. An attractive stipend is offered for 1 year, and at least 2 more years of support will be available following successful completion of qualifying doctoral-degree exams.

The University of Guelph is a growing (20,000 students) research-oriented institution situated in a pleasant city (100,000 population) in Southern Ontario, within 100 km of both Toronto and Niagara Falls.

Submit a letter of application, curriculum vitae, example(s) of writing proficiency, university transcripts and the contact information for 3 referees to:

Prof. J.C. Hall
Canada Research Chair in Recombinant Antibody Technology
Dept. of Environmental Biology
University of Guelph
Guelph, ON
N1G 2W1
Canada
jchall@uoguelph.ca

Posted: May 26, 2009


A postdoctoral position is immediately available to study regulatory posttranslational modifications involved in immunoreceptor signaling to transcription factor NF-kB and MAP kinases. Qualifications include a Ph.D., M.D., or the equivalent, a strong publication record in the biomedical sciences, and prior experience with protein/nucleic acid biochemical techniques (eg., immunoprecipitation, immunoblotting, RNA/DNA blotting), gene targeting vectors, and phenotypic analyses of the immune system in mutant mice (eg., FACS, cell proliferation, apoptosis assays). For consideration, please send a current CV and three letters of recommendation from past and/or present training mentors to dean.ballard@vanderbilt.edu.

Posted: May 20, 2009


A challenging POSTDOCTORAL POSITION is available at the Department of Pediatrics, University of Pittsburgh School of Medicine, to study the role of IL-17 in lung immunity with special reference to intracellular pathogens. The successful candidate should have a Ph.D. in Microbiology/ /Immunology/Molecular Biology, peer-reviewed publications, be highly motivated and be fluent in English. A fresh graduate with Ph.D degree is preferred. Prior experience with flow cytometry, immunofluorescence staining, confocal microscopy, molecular cloning, cell culture, standard microbiological techniques and animal handling skills are required. BSL-3 training is desirable but not required. Please send curriculum vitae, a brief research statement, and the names of three references via e-mail to Shabaana.Khader@chp.edu.

Shabaana A Khader, Ph.D.
Assistant Professor
Division of Medicine, Allergy and Immunology
Rangos Research Center
530 45th Street
Room 9130
Childrens Hospital of Pittsburgh
Pittsburgh

Posted: May 20, 2009


Post-doctoral positions - Immunological mechanisms of protection in human/animal vaccine development Center for Vaccine Development, University of Maryland

POSTDOCTORAL POSITIONS are available immediately at the Center for Vaccine Development (CVD) to join a multidisciplinary group that focuses on basic and translational studies in several models of infectious diseases directed to uncover the mechanisms underlying protective innate, cellular and antibody immune responses to a variety of microorganisms in volunteers and animals, chiefly in the areas of vaccine development and host-pathogen interactions. Exciting new studies include those directed to understand the mechanisms operative in the generation of mucosal immunity in the gut microenvironment in humans and its relationship to the microbiota. These investigations are a part of a prestigious NIAID-funded Cooperative Center for Translational Research in Human Immunology and Biodefense (Sztein, P.I.) about to start at the CVD. Studies include working with specimens obtained from children, adults and elderly subjects immunized with genetically engineered strains of Salmonella enterica serovar Typhi and Shigella vaccine candidates, as well as with malaria, hepatitis B, influenza and tularemia candidate vaccines. State-of-the-art immunological and molecular biology techniques (e.g., 14-color flow cytometry, gene expression microarrays, etc) are used to study antigen presentation, MHC-restriction, cloning and characterization of cytotoxic and helper T cells, identification of protective epitopes, role of dendritic and regulatory T cells, microarray profiling, systems biology and manipulation of cytokine production patterns to elucidate their role in the induction of innate, systemic and mucosal immune responses to vaccination and the mechanisms of immunosenescence.

The CVD offers a unique environment to study cellular and molecular determinants of protection to infectious diseases in humans. The CVD, largely supported by NIH funding and private foundations, has earned an international reputation for genetically engineering and testing vaccines against typhoid, shigella, cholera and malaria. Based at the School of Medicine, University of Maryland, Baltimore, the CVD was established in the mid-1970s as one of the first facilities to evaluate vaccines in community volunteers. It is one of only a handful of vaccine centers in the world engaged in the full range of vaccinology - from basic science through vaccine development, immunological studies, clinical evaluation and field studies.

The successful candidate should have a Ph.D. in Microbiology/Immunology or M.D. degree, experience in the study of immunological mechanisms, a strong publication track record, be highly motivated, have effective written and oral communication skills and hold a valid VISA to work in the US. Experience in flow cytometry and other CMI techniques, as well as molecular biology, microarray and/or tetramer technologies is highly desirable. Please send curriculum vitae, a brief outline of relevant research experience and interests and the names of three references via e-mail to Marcelo B. Sztein at msztein@medicine.umaryland.edu. Further information about the CVD can be found at: http://medschool.umaryland.edu/CVD/. The UM is an affirmative action/equal opportunity employer.

Marcelo B. Sztein, M.D., Professor of Pediatrics, Medicine and Microbiology and Immunology; Leader, CVD Immunology Group; Chief, Cellular Immunology Section and Flow Cytometry Core Laboratory; Center for Vaccine Development; University of Maryland; 685 West Baltimore Street; Rm. 480; Baltimore, Maryland 21201 * Phone: (410) 706-2345 * Fax: (410) 706-6205 * e-mail: msztein@medicine.umaryland.edu

Posted: May 19, 2009


A postdoctoral position is available immediately for a highly motivated individual to study cellular and molecular mechanisms of autoimmunity in mouse models of Multiple Sclerosis and Type 1 diabetes at Pennsylvania State University College of Medicine (http://pennstatehershey.org/web/microbiology/home). Strong background in immunology and molecular biology or biochemistry and the ability to work independently and cooperatively with other members in the laboratory is required (for relevant work see: Autoimmun Rev. 2009 Mar;8(5):400-4; J Immunol: 176(9), 5455-62, 2006; Nat Med: 11(3), 335-9, 2005). Candidates with previous experience in immunological analysis of mouse models are highly encouraged to apply. The candidate must have a Ph.D. or equivalent degree and should have less than 3 years of postdoctoral experience. The salary will be competitive and commensurate with qualifications and experience. Work location is within easy access to Philadelphia, Baltimore, and Washington, DC. Candidates should electronically submit their curriculum vitae with research interests and names and contact information for three references to: Hanspeter Waldner, Ph.D., Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA, 17033-0850. E-mail: hwaldner@hmc.psu.edu.

Posted: May 19, 2009


POSTDOCTORAL FELLOW – IMMUNOLOGY

A Postdoctoral position is available for a highly motivated individual in the laboratory of Dr. Dmitry Gabrilovich at H. Lee Moffitt Cancer Center and Research Institute. The research is focused on the analysis of immune responses to vaccination in cancer patients as well as on the study of cellular mechanisms of differentiation and function of dendritic cells (DC) and myeloid-derived suppressor cells (MDSC) in cancer. Areas of investigations include studies of the effects of tumor microenvironment on DC and MDSC and investigation of signal transduction and transcriptional regulation in these cells.

The successful candidate should have a strong background in immunology and molecular biology, and interests in tumor immunology and DC biology. Detailed knowledge and sufficient experience with flow cytometry, as well as experience working with human cells, are absolute requirements. The successful candidate will have excellent communication skills and command of the English language.

The laboratory is located in the NCI designated Moffitt Cancer Center, situated on the campus of the University of South Florida in Tampa. The research environment includes state of the art modern core facilities and pathogen-free modern animal facilities, access to clinical material, etc. Detailed description of the research interest of the laboratory and list of recent publications can be found at http://www.cancerbiology.usf.edu/gabrilovich.html.

Please visit www.moffitt.org/careers to apply online to Req 4617 and send CV, cover letter and three references to Dr. Dmitry Gabrilovich at Dmitry.Gabrilovich@moffitt.org.

Posted: May 15, 2009


Postdoctoral position in immunology and redox biology

A postdoctoral position is available immediately for a highly motivated individual interested in cellular and molecular mechanisms of autoimmunity. Qualifications: strong background in molecular biology, immunology, biochemistry and/or redox biology and the ability to work independently and cooperatively with other members in the laboratory. Immunological analysis of rodent models is desired. PhD or MD/DVM, or equivalent required. Salary: competitive and commensurate with experience. Review of applications will begin immediately, and will continue until the position is filled or closed. Send application letter, statement of interest and relevant work experience, CV and 3 references by e-mail to: Jay Reddy, MVSc, Ph.D., Associate Professor, Dept. of Veterinary & Biomedical Sciences, University of Nebraska-Lincoln, 202 VBS, Lincoln, NE 68583-0905; e-mail: nreddy2@unl.edu. University of Nebraska-Lincoln is committed to a pluralistic campus community through Affirmative Action and Equal Opportunity; and assures reasonable accommodation under the Americans with Disabilities Act.

Posted: May 15, 2009


Postdoctoral scientist position available in Immunology/ Biophysics/ Cellular imaging NYU Medical School, New York

A postdoctoral position is available immediately in the laboratory of Dr. Michelle Krogsgaard at the Department of Pathology and NYU Cancer Institute, NYU Medical School in New York to the role of self-ligands in TCR signaling using novel imaging and biophysical techniques (Krogsgaard, Mol Cell, 2003; Krogsgaard et al., Nature, 2005; Krogsgaard and Davis, NI, 2005).

Interested candidates should have a recent Ph.D. in immunology, molecular biology, biophysics, bioengineering or related fields. This position requires lab techniques including, but not limited to, advanced imaging techniques (confocal, live-cell imaging, TIRFM, FRET), cell culture, FACS analysis, cloning, protein chemistry /purification or other advanced biophysical techniques (X-ray crystallography and NMR). The successful candidate is expected to be highly motivated, creative and capable of contributing productively in a team environment. Excellent publication record and communication skills in oral and written English are essential.

The laboratory is located in the Smilow Research Center: http://www.med.nyu.edu/smilowcenter/, a new 13-story building with excellent research facilities on the NYU Medical School Campus located in mid-town Manhattan.

Salary and benefits will be commensurate with experience. Interested applicants should forward a cover letter summarizing current and future research interests (max 1 page), curriculum vitae, list of publications, and the names, telephone numbers and e-mail addresses of three references by e-mail to:

Michelle Krogsgaard, Ph.D.
NYU Cancer Institute
NYU School of Medicine, New York
e-mail: krogsgaard.lab@gmail.com
phone: 212 263 9266
Web: http://www.med.nyu.edu/research/krogsm01.html

Posted: May 5, 2009


Postdoctoral Position in Immunology and Cell Biology

An NIH supported postdoctoral position to study the cell biology of Toll-like receptors is available in the laboratory of Cynthia Leifer, Department of Microbiology and Immunology, Cornell University. TLRs generally recognize microbe specific structures, with the exception being nucleic acids. Due to the conserved structure of nucleic acids, response is tightly regulated to prevent autoimmunity. The overall goal of this research is to understand this regulation at the molecular and cell biological level. Current projects focus on TLR9 as a model and include identification and characterization of interacting proteins, intracellular trafficking and post-translational modifications that regulate response to ligand. Candidates for post-doctoral positions should be highly self-motivated and already possess expertise in basic cell biology techniques, molecular biology, microscopy/imaging and have extensive knowledge of immunology.

Applicants should send a statement of research goals, CV and references to Cal59@cornell.edu.

Cornell University is an equal opportunity, affirmative action educator and employer.

Cynthia A. Leifer, Ph.D.
Assistant Professor of Microbiology and Immunology
VMC C5-153
Cornell University
Ithaca, NY 14850
www.vet.cornell.edu/microbiology/faculty/Leifer/

 
 

Postdoctoral Position in Mucosal Innate Immunity

A postdoctoral position is available on mucosal innate immunity in the laboratory of Cynthia Leifer, Department of Microbiology and Immunology, Cornell University. Toll-like receptors play a fundamental role in mucosal homeostasis and in responses to pathogens at mucosal surfaces. Using a combination of in vitro and in vivo approaches we seek to uncover the very early responses of intestinal epithelial cells to pathogen exposure. Candidates should be highly self-motivated and already possess significant experience in animal handling, flow cytometry, tissue staining, microscopy/imaging, basic cell biology techniques and have extensive knowledge of immunology.

Applicants should send a statement of research goals, CV and references to Cal59@cornell.edu.

Cornell University is an equal opportunity, affirmative action educator and employer.

Cynthia A. Leifer, Ph.D.
Assistant Professor of Microbiology and Immunology
VMC C5-153
Cornell University
Ithaca, NY 14850
www.vet.cornell.edu/microbiology/faculty/Leifer/

Posted: May 4, 2009


Post doctoral positions - Engineering an Artificial Lymph Node

Three highly motivated postdoctoral researchers are required to join the groups of Dr. Mark Coles, Prof. Abraham Stroock and Dr. Tom Cupedo, to work on a Human Frontiers Science Program funded project. The research will focus on the role of physiological forces in lymph node development, organization and function leading to the engineering of an artificial lymph node (Nature Immunology 2009, 10(1): 66-74, Nature 2007, 446: 547-51, Nature 2008, 455: 208-212). The project involves using tissue engineering (nanobiotechnology), advanced imaging technologies and gene expression analysis to analyze physiological forces in lymph node development. Each of the postdocs will be located in one of the respective labs (York, Ithaca, Rotterdam), however the positions will require travel and short term placement in the partner labs. You should possess a Ph.D. in a relevant field.

Contacts:

Dr. Mark Coles
Centre for Immunology and Infection
University of York, York, UK
mc542@york.ac.uk
www.york.ac.uk/res/cii/people/Coles-Mark.shtml

Prof. Abraham Stroock
Chemical and Biomolecular Engineering
Cornell University
Ithaca, NY, USA
ads10@cornell.edu
www.cheme.cornell.edu/people/profile/index.cfm?netid=ads10

Dr. Tom Cupedo
Department of Haematology
Erasmus Medical Center
t.cupedo@erasmusmc.nl
www.erasmusmc.nl/hematologie/ond/hematopoiese-transplantatie/392562/?lang=en

Posted: May 4, 2009


We have a post-doctoral position available starting 7/1/09. Qualified candidate has training in immunology and is interested in examining CNS
innate immune responses that lead to chemokine expression during WNV encephalitis. Must be US citizen.

Contact:

Robyn S. Klein, M.D., Ph.D.
Associate Professor
Washington University School of Medicine
Departments of Internal Medicine & Neurobiology
Campus Box 8051
660 S. Euclid Ave
St. Louis, MO 63110
Phone: (314) 286-2140
Fax: (314) 362-9230
rklein@id.wustl.edu

Posted: April 29, 2009


POSTDOCTORAL POSITION – Cell Signaling in Malaria Innate Immunity

An NIH-funded postdoctoral position is available to start on 1 July 2009 on the systems biology of cell signaling in the context of malaria innate immunity. The fellow will be responsible for characterization of the crosstalk and downstream targets of the MAPKs and related signal transduction pathways that regulate innate immunity to malaria parasite infection. The fellow will be expected to work with several biological systems, ranging from invertebrate to mammalian models. Minimum requirements include a Ph.D., evidence of peer-reviewed publications, and 0-2 years of postdoctoral training with strong background in cell signaling and molecular biology. Expertise in malaria or with other eukaryotic parasites is a significant plus, but is not required. Please send a cover letter with a statement of career goals, curriculum vitae, and names and addresses (including e-mail) for three references to sluckhart@ucdavis.edu.

Contact:

Shirley Luckhart, Ph.D.
Associate Professor
Department of Medical Microbiology and Immunology
School of Medicine, 3437 Tupper Hall
One Shields Avenue, Davis, CA 95616
Tel: (530 754-6963
Fax: (530) 752-8692

Posted: April 29, 2009


Postdoctoral Position At The University Of Minnesota
NK cell Development and Functional Maturation


A postdoctoral position is immediately available to study human NK cell development from CD34+ hematopoietic progenitors using a newly developed model system. The project will focus on: 1) the characterization of NK developmental stages, 2) investigating the influence of environmental signaling pathways provided by stroma and 3) determination of the molecular mechanisms that govern both commitment to the NK cell lineage and functional maturation.

The successful candidate will have a Ph.D. or M.D. degree and a track record of accomplishments. Experience with cell culture, basic immunological and molecular techniques are required. Studies will also rely heavily on multicolor FACS analysis and spectral imaging.

Applicants should send curriculum vitae, statement of research interests and intentions, and three letters of reference to:

Michael R. Verneris, M.D.
Assistant Professor
Department of Pediatrics
Division of Blood and Marrow Transplantation
University of Minnesota
Verneris@UMN.edu

The University of Minnesota is an equal opportunity/affirmative action employer; women and members of minority groups are strongly encouraged to apply.

Posted: April 29, 2009


Postdoctoral Position At The University Of Minnesota
Immune Reconstitution After Umbilical Cord Blood Transplantation


A postdoctoral position is immediately available to study immune reconstitution after umbilical cord blood transplantation. The project will focus on the restoration of T cell immunity (i.e. subsets and function) after partially HLA-matched single and/or double umbilical cord blood transplantation.

The successful candidate will have a Ph.D. or M.D. degree and a track record of accomplishments. Experience with cell culture, basic immunological and molecular techniques are required. Studies will also rely heavily on multicolor FACS analysis.

Applicants should send curriculum vitae, statement of research interests and intentions, and three letters of reference to:

Michael R. Verneris, M.D.
Assistant Professor
Department of Pediatrics
Division of Blood and Marrow Transplantation
University of Minnesota
Verneris@UMN.edu

The University of Minnesota is an equal opportunity/affirmative action employer; women and members of minority groups are strongly encouraged to apply.

Posted: April 29, 2009


The Department of Pathology at University of Virginia Health System is seeking applications for a Research Associate position to work in the laboratory of Dr. Timothy Bullock, Department of Pathology and Humane Immune Therapy Center; http://www.healthsystem.virginia.edu/internet/pathology/Faculty/bullock.cfm, in assessing molecular differences in human T cell responses to cancer vaccines. Position available immediately for individuals with Ph.D., M.D., or M.D. /Ph.D. The ideal candidate will have extensive experience working with antigen specific T cells, with a preference for those with skills in the genetic modification of T cells and gene expression profiling.

Applicants must apply at http://jobs.virginia.edu. Search on posting number 0603437; then, complete a Candidate Profile online and attach a curriculum vitae and contact information for three references.

The University of Virginia is an Equal Opportunity/Affirmative Action Employer.

Posted: April 24, 2009


POSTDOCTORAL POSITIONS-lymphocyte signaling transduction
 
Positions are available immediately to study the regulation of signal transduction in lymphocytes by protein ubiquitination (Immunity, 21:167, 2004; Mol. Cell, 21:135, 2006; Nature Immunol., 9:245, 2008). We are using mouse models and molecular biochemical approaches to study the deficiency of E3 ubiquitin ligases in the development and activation of leukocytes, and their role in autoimmune and inflammatory diseases. Prior experience in molecular and cell immunology techniques, handling of mouse models, and a strong background in immunology are desired.
 
Please send CV and three names of references to Yun-Cai Liu, Ph.D, Member, Division of Cell Biology, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA. Email: yuncail@liai.org; http://www.liai.org/.

Yun-Cai Liu, Ph.D
Member and Professor
Division of Cell Biology
La Jolla Institute for Allergy and Immunology
9420 Athena Circle
La Jolla, CA 92037
Tel: 858-752-6810
Fax: 858-752-6985
email: yuncail@liai.org
http://www.liai.org

Posted: April 24, 2009


POSTDOCTORAL POSITIONS – VACCINE IMMUNOLOGY
University of Rochester Medical Center, Rochester, New York
Principal Investigator: Mingtao Zeng, Ph.D., Assistant Professor
 

Two postdoctoral positions are available in the Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York. Highly motivated individuals are sought with a strong interest in influenza virology, immunology, and vaccine development. Successful applicants must have a Ph.D. in immunology, virology, microbiology, or a related biological science. The positions will be funded by research grants from the National Institutes of Health. US citizens or permanent residents are preferred but not required. We encourage and facilitate career development of postdoctoral researchers to independence. An outstanding candidate may be offered a research faculty position. Salary and benefits commensurate with experiences. Interested individuals should send their curriculum vitae, a one-page statement of research experience and interests, and at least three names of references to Dr. Mingtao Zeng by email: Mingtao_Zeng@urmc.rochester.edu.

The University of Rochester has long been considered one of the top research institutions in the USA. The Department of Microbiology and Immunology ranks among the top 20 in the nation for NIH grant support. For more information about the research in Dr. Zeng’s laboratory, please visit: http://www.urmc.rochester.edu/SMD/mbi/faculty/zeng.htm.

Posted: April 24, 2009


We are seeking a postdoctoral fellow to embark on a research project based upon our publication, "Control of thymocyte development and recombination-activating gene expression by the zinc finger protein Zfp608" (Nature Immunology 7: 1309-1316, 2006). The candidate should hold either a Ph.D. or M.D. degree with a strong background/experience in molecular biology as well as mouse husbandry. Candidates should submit their CV, list of publications, a cover letter describing research accomplishments and career goals, and contact information of three references to:

Thomas M. Aune, Ph.D., Professor, Department of Medicine, Vanderbilt University School of Medicine, via email: tom.aune@vanderbilt.edu.

Thomas M. Aune, Ph.D.
tom.aune@vanderbilt.edu
MCN T3219
Vanderbilt University Medical Center
1161 21st Ave. S.
Nashville, TN 37232
(615) 343-7353
(615) 322-6248

Posted: April 23, 2009


POST DOCTORAL POSITIONS – The University of Michigan Medical School, Ann Arbor, Michigan

Post-doctoral positions are available immediately for highly motivated individuals for the following projects.

Study the molecular mechanisms for CD4 T cell selection on thymocytes and their effector function: Thymocyte-selected CD4 T cells share many characteristics found in NKT cells, i.e., SAP-dependent development and Stat6 independent IL-4 production. Nevertheless, they are two distinct populations with different antigen specificity. The long-term goal of our research is to investigate the CD4 T cell population selected on thymocytes to have a better understanding of the regulatory mechanisms for their development and function during the immune response. CD4 T cell selection by MHC class II expressing thymocytes likely play an important role in T cell-mediated immunity in humans.

A strong background in cellular and molecular immunology, particularly experience in T cells, is highly desired. The position requires familiarity with murine models, flow cytometry, molecular biology, and lymphocyte separation, culture and assay techniques. Excellent verbal, written communication and organization skills and an ability to handle multiple projects simultaneously are required.

Interested applicants with a Ph.D. or M.D. should email a curriculum vitae with a description of research interests and names of three references with email addresses to: heechang@umich.edu.

Cheong-Hee Chang, Ph.D.
5641 Med Sci II
Department of Microbiology and Immunology
University of Michigan Medical School
Ann Arbor, MI 48109

Posted: April 22, 2009


A postdoctoral position is available in the Department of Microbiology & Immunology at University of Texas Medical Branch to study adaptive immunity to West Nile virus infection. Our lab is interested in understanding host immunity in protection and pathogenesis during West Nile virus infection. The candidate should hold either a Ph.D. or M.D. degree with a strong background/experience in cellular immunology as well as animal (mouse) experiments. Candidates with a strong desire and commitment to conduct research in viral immunology should submit their CV, list of publications, and contact information of three references to:

Dr. Tian Wang
, Department of Microbiology & Immunology, Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, Office: (409) 772-3146; Fax: (409) 772-3338; E-mail: ti1wang@utmb.edu.

Posted: April 21, 2009


Postdoctoral position: Immunity and host defense
 
A Postdoctoral position is available in the Department of Microbiology and Immunology at Northwestern University to study the functions of CD1 and MHC class Ib molecules in infectious disease and T cell development.  Applicants should have a Ph.D. in Immunology or Microbiology.  Experience in mouse models of infectious disease (e.g. Listeria and Mycobacteria) and cellular immunology is preferred.  Qualifications also include strong interpersonal skills, excellent communication and organizational skills, an ability to work independently, and commitment to laboratory research.  Interested applicants should send their CV, along with contact information of three references, and a cover letter describing research accomplishments and career goals electronically to Dr. Chyung-Ru Wang (email: chyung-ru-wang@northwestern.edu)
 
Dr. Chyung-Ru Wang
Professor
Department of Microbiology and Immunology
Northwestern University
320 E. Superior Street, Searle 3-401
Chicago, IL 60611
Email: chyung-ru-wang@northwestern.edu 

Posted: April 16, 2009


Ph.D. Student Position in Leukocyte Recruitment

The laboratory of Dr. Lixin Liu in the Dept. of Pharmacology at the University of Saskatchewan has a position currently opening for a PhD student to study the cellular and molecular mechanisms of leukocyte recruitment during inflammation. 

This laboratory is equipped with a new intravital microscope system and is interested in the role of intracellular signaling molecules in leukocyte recruitment. The current focus in the lab is on the role of LSP1 and PI3K in neutrophils and in endothelial cells during neutrophil-endothelial cell interactions using mouse models. The techniques used are intravital microscopy and cell biology and biochemistry techniques. For more information please visit the website (http://www.medicine.usask.ca/pharmacology/research/lixin-liu-ph-d) and check the additional recent publications (Am J Physiol Heart Circ Physiol 2008, 294(6):H2524; Blood 2008, 111(9):4828 and J Cell Sci 2008; 121(Pt 2):205). 

The applicant should have a master degree in immunology, inflammation, cellular biology, biochemistry or in related fields, excellent laboratory skills and communication skills in English, enthusiasm in research and ability to work independently and in a team environment. Experience in research using mouse models and/or cell-cell interactions will be a plus. The requirements for a foreign candidate can be found at the CGSR website: http://www.usask.ca/cgsr/. 

Applicants should submit a CV, list of publications, names and detailed contact information of three referees via email to lixin.liu@usask.ca, or fax to Lixin Liu at 306-966-6220, or in mail to Dr. Lixin Liu, Dept. of Pharmacology, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchewan, Canada S7N 5E5.

Posted: April 16, 2009


Postdoctoral Fellowship at the University of Alabama at Birmingham

A postdoctoral position at the University of Alabama at Birmingham is immediately available to study lymphocyte development and members of a novel family of Fc receptor-like (FCRL) molecules. FCRLs possess tyrosine-based regulatory potential and are expressed by distinct populations of B cells and cytotoxic lymphocytes (Annu Rev Immunol. 2007;25:525-60. PMID: 17201682). Current work in the laboratory focuses on exploring their biological roles in human and mouse models as well as their importance in malignancies and autoimmune disorders.

Dr. Davis: UAB Faculty Profile

A strong background in basic cellular immunobiology is required. Familiarity with molecular biology, flow cytometry, and biochemistry techniques are highly desirable. Suitable candidates should be able to communicate well verbally and work independently.

Ph.D. and/or M.D. degree is required. Applicants please send curriculum vitae with a description of research interests and names of three references with email addresses to:

Randall S. Davis, M.D.
Associate Professor of Medicine, Microbiology, and Biochemistry & Molecular Genetics
University of Alabama at Birmingham
1825 University Blvd SHEL412
Birmingham, AL 35294-2182
TEL: (205) 934-1522
FAX: (205) 934-1875
Email: randall.davis@ccc.uab.edu

Posted: April 15, 2009


Postdoctoral Fellows

Post-doctoral Position in Lung Immunopathology, Brigham and Women's Hospital and Harvard Medical School

Postdoctoral fellow positions are available in the Gao Lab at Brigham and Women's Hospital, an affiliate of Harvard Medical School. The ongoing research will focus on expression and regulation of Stat3 transcription factor and complement 5a receptors, C5aR/C5L2 and their roles in acute lung injury and sepsis along with other lung gene therapy projects. Strong backgrounds in molecular biology are particularly sought. Extensively trained skills in animal manipulation are a plus. Good command of English required.

Please send the detailed CV along with any publication in PDF format to:

Hongwei Gao, M.D., Ph.D.
Assistant Professor
Center for Experimental Therapeutics and Reperfusion Injury
Department of Anesthesiology, Perioperative & Pain Medicine
Brigham and Women's Hospital and Harvard Medical School
20 Shattuck Street, Thorn 704, Boston, MA 02115
Phone: 617-732-7454
Fax: 617-264-5142
Email: hgao@zeus.bwh.harvard.edu (preferred)

Posted: April 14, 2009


Researcher/Supervisor: Dr. Shiguang Yu
Arkansas State University – Arkansas Biosciences Institute

View complete details and application taken only on-line: https://jobs.astate.edu [required applicant documents: 1.on-line application, 2.cover letter, 3.curriculum vitae, 4.statement of current and/or future research interest, and 5.reference list.]

Position Summary: Studying mechanisms by which dysfunctional immune cells mediated autoimmune inflammation. (J. Immunol. 2006, 176:1259-1265. J. Exp. Med. 2006, 203:349-358. J. Immunol. 2008, 181:2238-2245. J. Immunol. 2008, 180:7706-7713). This is a multi-disciplinary position incorporating areas of mouse models, molecular/cellular immunology, and protein biochemistry.

The post-doc will focus on and perform the following activities:
  • Conduct experiments requiring cell culture and flow cytometry, cryostat section, immunohistochemical staining, genetic typing mouse, ELISA, RT-PCR, western analyses, antibody purification techniques
     
  • Perform cell transfer and mouse blood and tissue collection
     
  • Participate in grant writing and publication preparation as well as oral presentations
     
  • Assume primary responsibility of equipment operation, perform data analysis and reduction, create and establish quality assurance protocols

In addition to scientific skills stated above, the individual should have good written and verbal communication skills, ability to work independently, fulfill project goals and meet deadlines, and ability to perform research and publish results in peer-reviewed literature.

Minimum Qualifications: Ph.D. or M.D. with background in Immunology or related fields and a strong record of research productivity required.

Desired Qualifications: Previous research experience in immunology area, cell culture, flow cytometry preferred. Experience in animal model of disease; ability to multi-task and work in a cross-disciplinary environment are advantageous.

Posted: April 13, 2009


Postdoctoral Position

Postdoctoral position available immediately in an NIH-funded laboratory to investigate the mechanism of microbial pathogenesis in preterm birth, utilizing a pregnant mouse model established in our laboratory. For recent publications, please see J. Immunol. 2007, 179:2501-2508; J. Biol. Chem. 2007, 282:25000-25009 & 2009, 284:3865-3872; and J. Clin. Microbiol. 2009, 47:38-47. We seek a motivated individual to investigate the host innate immune responses to the bacterial infection and for vaccine development. Qualifications should include but are not limited to a strong background in molecular biology and immunology and experience of working with rodents. Experience in real-time PCR and flow cytometry is a plus. Contact: Dr. Yiping Han, Associate Professor, Departments of Periodontics and Pathology, Case Western Reserve University, Cleveland, OH 44106, Phone: (216) 368-1995, Email: yiping.han@case.edu.

Posted: April 13, 2009


POSTDOC FELLOW

We are seeking a Postdoc Fellow to provide research within our Nanotechnology Characterization Lab. This lab provides pre-clinical assessment/characterization of nanoparticles and devices that will be used for cancer research. This opportunity will focus on the investigation of nanoparticle interaction and effects on the immune cell function. The project will involve both primary cell culture/lines. Individual will work with a team of scientists to study routes of nanoparticle uptakes by the immune cells, intracellular fate of the particles, particle effects on intracellular signaling pathways and the role of particle physiochemical properties on particle-cell interactions.

Experience required: Ph.D. in Immunology, Cell Biology, Molecular Biology or related discipline from an accredited college or university and no more than 2 years of postdoctoral training after graduation. Foreign educated candidates who have completed part or all of their education outside of the U.S. must have their foreign education evaluated by an SAIC-approved accreditation organization to assure that it has met the equivalency of the qualifications of the degree work in the United States.

Required skills include: signaling pathway bioanalytical characterization, primary cell and tissue culture hands-on-skills, strong knowledge of inflammatory pathways, antigen presentation and/or blood coagulation. Experience with or knowledge gained through education of analytical instrumentation used to study the immune cells. Desired but not required skills include: training and expertise with inflammatory protein and gene expression tools, previous experience with nanomaterials, ability to work independently in a cross-disciplinary setting; basic bioinformatic skills to support quantitative analysis of experimental data.

To apply: Please send your resume to www.SAIC-Frederick.com and apply for the Post Doc Fellow position 142041.

SAIC-Frederick, a wholly owned subsidiary of SAIC, is helping to speed the delivery of new technologies and treatments to patients with Cancer and AIDS. We operate the laboratories at the National Cancer Institute at Frederick. We are a staff of more than 1,700 scientific, technical and support professionals conducting basic and applied research in cancer and AIDS. SAIC operates and manages the federal government’s only vaccine manufacturing facilities, runs the high-performance Advanced Biomedical Computing Center, and supports more than 300 clinical trials treating patients in the US and around the world.

Posted: April 10, 2009


Postdoctoral Position Available
Principal Investigator: David LaRosa, MD, Assistant Professor of Medicine
Allergy-Immunology Section, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

A postdoctoral position is available for scientists interested in innate immunity, studying the role of mast cells in host defense and immunoregulation. Mouse infection models will be used to dissect the role of mast cells early in the inflammatory response and in chronic infection.
Applicants must have a Ph.D. or M.D., or equivalent.  Experience in cellular and molecular immunology, flow cytometry, mouse models of infection, and immunoflorescence microscopy are highly desired. Salary is commensurate with experience. The position is available currently and funding is expected for 2-3 years.

To apply, please send CV, contact information of three references, and a one-page summary of research background and interests to:

David LaRosa: dlarosa@mail.med.upenn.edu

Posted: April 6, 2009


Post-doctoral position in Immunology/Cell Biology, New York City, USA

Post-doc positions are currently available within the Blander laboratory at the Immunology Institute, Mount Sinai School of Medicine in New York City. Our research is primarily focused on the fundamental cellular processes accompanying innate immune responses and how these processes control the adaptive immune response. Project 1 will address the characterization of the molecular pathways triggering TH17 cell development in response to innate immune recognition of infected apoptotic cells, a new physiological signal for TH17 cell differentiation which we have recently identified. Project 2 will address the cell biology and molecular basis underlying the control of phagosome maturation and antigen presentation by Toll-like receptors, an area of study which we have pioneered. The prospective post-doctoral researcher is expected to be highly motivated and possess a strong background in immunology, and/or expertise in molecular biology, cell biology and imaging technology, or protein chemistry and proteomics. Applications from graduate students at the end of their training program are particularly encouraged. Prior experience with mouse genetics and animal handling is valuable but not required. Salary is based on NIH scale and includes excellent benefits.

Interested applicants should send a statement of research goals, curriculum vitae, and contact information for three professional references to Dr. Julie Magarian Blander at julie.blander@mssm.edu.

Julie Magarian Blander, Ph.D.
Assistant Professor, Department of Medicine, Immunology Institute, Mount Sinai School of Medicine, 1425 Madison Avenue, 12-20G, New York, NY 10029 * www.iisinai.org * www.searlescholars.net/people/2007/blander.html

Posted: April 6, 2009


Postdoctoral Fellow

A Postdoctoral Fellowship is immediately available to study the mechanisms by which acute maternal alcohol intoxication impairs lung innate and adaptive immunity in the infant. Ongoing projects include understanding how respiratory tract viral infections in the setting of perinatal alcohol exposure result in chronic lung disease. This position is being offered through the Biomedical Alcohol Research Training Program at the LSU Health Sciences Center in New Orleans and is funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) as part of the National Research Service Award program. Salary opportunities will be highly competitive. Applicants should be highly motivated with a strong background in pulmonary inflammation, immunology, alcohol research, and/or in the use of rodent models of airways disease. Minimum requirements are an MD, PhD, or equivalent. LSUHSC is an EEO/AA Employer. Please send a cover letter regarding research accomplishments and interests, curriculum vitae, and the names and contact information of three references to:

Dr. Stephania Cormier, Alcohol Research Center, Department of Pharmacology and Experimental Therapeutics, LSU Health Sciences Center, 1901 Perdido St, Box P7-1, New Orleans, LA, 70112; Fax: 504-568-2361; Email: scorm1@lsuhsc.edu.

Posted: April 6, 2009


Post-doctoral position in leukocyte recruitment/inflammation 

A post-doctoral research position is available immediately in the laboratory of Lixin Liu at the University of Saskatchewan to study the cellular and molecular mechanisms of leukocyte recruitment during inflammation.

This laboratory is interested in the role of intracellular signaling molecules in leukocyte recruitment. Our current focus is on the role of LSP1 and PI3K in neutrophils and in endothelial cells during neutrophil-endothelial cell interactions using mouse models. The techniques used are intravital microscopy and cell biology and biochemistry techniques. For more information please visit the website -- http://www.medicine.usask.ca/pharmacology/research/lixin-liu-ph-d -- and check the additional recent publications (Am J Physiol Heart Circ Physiol 2008, 294(6):H2524; Blood 2008, 111(9):4828 and J Cell Sci 2008; 121(Pt 2):205).

The applicant should have a PhD degree, a strong background in immunology, cellular biology or biochemistry or in related field, excellent communication skills in English, and at least one publication in reputable scientific journal. Experience in research using mouse models and/or cell-cell interactions will be a plus.

Applicants should submit a CV, list of publications, names and detailed contact information of three referees via email to lixin.liu@usask.ca, or fax to Lixin Liu at 306-966-6220, or in mail to Dr. Lixin Liu, Dept. of Pharmacology, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchewan, Canada S7N 5E5.