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To Whom It May Concern: I am seeking a position as a Research Associate or Senior NIH Postdoctoral Fellow in the field of Tumor Immunology. I received my Ph.D. from the University of Pennsylvania’s Immunology Graduate Group. My thesis was on the in vitro T cell immune response to human melanoma and how it paralleled that response in vivo. My lab was the first in this country to document in vitro autologous T cell responses to melanoma and the first lab to clearly demonstrate that cultured primary, but not metastatic melanoma cell lines presented exogenous antigen to HLA-matched antigen specific T cell clones. Since then I have gained a great deal of experience in molecular biology though my work with HIV mutant viruses and DNA sequencing/genotyping for the U. of P. Genetics Department. However I excel at T cell regulation of the immune system. I have developed a keen interest in antigen presentation by dendritic cells and how it can dictate the nature of the T cell response. One interesting aspect of this is the “vaccine effect” of some anti-cancer chemotherapeutic agents. This phenomenon is related to the type of cell death (apoptosis) induced by some agents and the unique ability of dendritic cells to process and present immunogenic peptides to memory precursor T cells. I would like to study this mechanism in detail and identify how some, but not all anti-cancer compounds do this. This would ultimately lead toward development of a new class of anti-cancer agents that would not only remove the initial cancer, but would protect the host from recurrences. In addition to this I would like to work in the tumor vaccine field since there are some exciting results being developed using dendritic-tumor fusion hybrids. In my last position as a Senior NIH Fellow I developed a T cell hybridoma-based method to identify T cells that were responsible for graft vs. host disease during transplant therapy for leukemia. Unfortunately after a year the NIH budget of the lab was cut and so was my position. If you can identify a position that suits my background please feel free to contact me. Thanks for your time. Sincerely yours, Michael Alexander, Ph.D. E-mail: malexand@mail.jci.tju.edu C/V attached Website: http://careers.beyond.com/4497307. Posted: February 25, 2008 |
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TO WHOM IT MAY CONCERN
Myself Suhail Tahir would like to introduce my
self as a Ph.D. in Biotechnology (immunology, Molecular Biology and cell
biology) from Bundelkhand. University, jhansi, India. As I
have completed my masters in 2003 and have gained two and half year
research experience in Immunology while working on B cell biology of
Streptococcus pneumoniae, I am looking for promising PhD position
in an esteemed research group. I have
enclosed my C.V. for your consideration and perusal. Posted: May 9, 2007 |