The American Association of Immunologists

POSTDOCTORAL POSITIONS are available for research on intestinal immune homeostasis and intestinal inflammatory responses.

The laboratory focuses on understanding immunological pathways in inflammatory bowel disease, with a particular focus on those pathways that have been implicated through genetic studies in human inflammatory bowel disease. The current position will investigate Innate Immunity and Host Pathogen interactions, and mucosal immunity, including the regulation of innate cells and pattern recognition pathways. These involve combined studies in both primary human immune cells and mouse model systems.

Education and experience: Candidates must have a PhD or equivalent degree with a strong background in immunology and/or molecular biology and biochemistry. Experience in cellular and molecular immunology, biochemistry, molecular biology, multiparameter flow cytometry, gene expression analysis, and human peripheral and intestinal cell isolation is desired.

To apply: Please send curriculum vitae, three names of reference and a one page summary of research background and interests to Clara Abraham, M.D. (Clara.Abraham@yale.edu).

Yale University is an Affirmative Action/Equal Opportunity Employer.

A Postdoctoral Fellowship is available in the laboratory of Dr. Hongbo Chi in the Department of Immunology, St. Jude Children’s Research Hospital, to investigate lymphocyte signaling and metabolism in the immune system. We are particularly interested in dissecting the signaling and metabolic pathways mediated by the kinases mTOR and MAPK in basic T cell and dendritic cell biology. We also investigate molecular mechanisms of autoimmune and infectious diseases (multiple sclerosis, colitis and listeriosis). The experimental models include genetically-modified mice and primary immune cells derived from these mice, as well as in vitro systems to explore signaling, transcriptional and epigenetic regulation. Please see the following articles (Nature Immunol 13:152 (2012); Nature Immunol 12:888 (2011); Immunity 35:45 (2011); J Exp Med 208:1367 (2011); and Nature Rev Immunol 12:325 (2012)) and the website (www.stjude.org/chi) for additional information.

Highly motivated individuals with a recent Ph.D. in immunology, biochemistry, or cell biology, with evidence of scientific accomplishment, are encouraged to apply.

To apply: Please send curriculum vitae including a list of three references to: Elizabeth.Phillips@stjude.org.

Several opportunities available at NIAID/NIH!

The National Institute of Allergy and Infectious Diseases (NIAID), one of the largest Institutes of the world-renowned National Institutes of Health (NIH), conducts and supports a global program of biomedical research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. NIAID is at the forefront of research and discovery in areas such as HIV/AIDS, pandemic influenza, malaria, tuberculosis, vaccine research, and many more.

Make a difference!

A talented and diverse workforce is one of NIAID’s greatest assets, and we seek qualified candidates to help us make a difference in the lives of millions around the world. Join NIAID’s scientific workforce and play a key role in developing and implementing programs that support a broad range of cutting-edge clinical, basic, and translational research.

Your individual talents are needed to support NIAID’s mission.

NIAID boasts state-of-the-art facilities and highly trained staff who seek new and improved ways to understand, treat, and prevent infectious and immune-mediated diseases. NIAID also offers competitive salaries and a comprehensive benefits package, including retirement; health, life, and long-term care insurance; annual and sick leave; and a thrift savings plan (401[k] equivalent).

Learn more about NIAID and its exciting career opportunities:

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HHS, NIH, and NIAID are proud to be equal opportunity employers.

A post-doctoral position is available for Innovative projects that focus on innate immune mechanisms triggering adaptive immune responses in lupus. The projects include: novel pathways that regulate macrophages (cutaneous and kidney), identifying aberrant macrophages linked to lupus, and determining the unique and shared role of the principle macrophage developmental molecules in immune mediated inflammation. Unique transgenic strains and knockout mice with reporter genes have been constructed on lupus-susceptible strains for these projects. These projects in mice have human translational components in patients with cutaneous lupus and lupus nephritis (biomarkers, therapeutic targets).

Required Experience:

Immunology and Molecular/Cell Biology
In vivo mouse systems
Computer literacy

Desired:

Experience with macrophages
Responsible, hard-working individual who is able to multi-task and to work independently

M.D. or Ph.D. required.

To apply: Please send CV and three references. Interested candidates contact:

Vicki Rubin Kelley, Harvard Institutes of Medicine, 4 Blackfan Street, Boston, MA 02115; FAX 617-525-5830; e-mail: vkelley@rics.bwh.harvard.edu.

The U.S. Department of Agriculture (USDA), Agricultural Research Service (ARS), Virus and Prion Research Unit (VPRU), located in Ames, IA, is seeking a POSTDOCTORAL RESEARCH ASSOCIATE, (Research Microbiologist, GS-0403-11) for a full-time, TWO YEAR APPOINTMENT. Recent (within last 4 years) Ph.D. is required. Salary $57,408 - $74,628 per annum (commensurate with experience plus benefits).

The incumbent will conduct research on the study of immunogenicity and efficacy of different influenza virus vaccines for pigs. The lab is focused on enhancing swine health through improved diagnostics and vaccines with a focus on respiratory diseases. New state-of-the-art laboratory and animal space will provide amble opportunity for a motivated individual to work in a natural host.

Seeking candidates with knowledge in immunology and virology with skill in cell-culture, ELISA, ELISpot and/or flow cytometry and knowledge of animal models and research techniques.

Applications for this position will be accepted from both US Citizens and Foreign Nationals who meet both Appropriations Law and Immigration Law requirements found under “Foreign Nationals Eligible for Federal Employment” at http://www.afm.ars.usda.gov/hrd/EmployForeignNationals/index.htm.

To apply: Send application materials (CV and cover letter) and references to Dr. Crystal Loving, USDA/ARS Virus and Prion Research Unit, P.O. Box 70, 1920 Dayton Ave., Ames, Iowa 50010 or e-mail (crystal.loving@ars.usda.gov).

USDA/ARS is an equal opportunity provider and employer.

An NIH-funded postdoctoral position is available immediately to study the immunobiology of donor-specific negative vaccination in murine models islet cell and vascularized organ transplantation in the laboratory of Dr. Xunrong Luo at the Comprehensive Transplant Center of Northwestern University. The long-term objective of this project is the translational application of a tolerogenic negative vaccination protocol in large animal models and eventually in clinical settings of islet cell and solid organ transplantation. The successful candidate will closely interact with the PI as well as with co-PIs Dr. Steve Miller at Northwestern University and Dr. Bernhard Hering at University of Minnesota to investigate the mechanisms of preemptive negative vaccination on tolerizing anti-donor cellular and humoral immunity, and therapeutic strategies particularly in setting of prior sensitization. He/she will utilize an array of techniques (in vivo mouse models of transplantation, tissue culture, cell characterization by FACS, ELISPOTs, Luminex, transcriptome analysis, etc.) to determine the nature and magnitude of anti-donor responses. The successful candidate will also be encouraged to apply for external fellowships from the Juvenile Diabetes Research Foundation, the American Society of Transplantation, the American Society of Transplant Surgeons, and/or the American Society of Nephrology. This position will provide an opportunity to build a novel set of skills and expertise that prepare the candidate for his/her independent research career.

Salary and benefits will be competitive.

Requirements: Successful applicant will be a highly motivated individual preferably with a strong background in cellular immunology. Applicants must have a Ph.D. or M.D., and preferably with no more than 5 year of postdoctoral experience. Applicant should be proficient in communication in English.

Contact Person: Xunrong Luo, M.D., Ph.D., Associate Professor of Medicine, Surgery, Microbiology and Immunology, Medical Director, Human Islet Transplant Program, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Searle Research Building 10-525, Chicago, IL 60611; Phone 312-908-8147; Fax 312-503-0622; Email xunrongluo@northwestern.edu.

To apply: Interested applicants should submit 1) cover letter briefly describing your research accomplishments, interests, and career goals, 2) your CV, and 3) contact information of three references to xunrongluo@northwestern.edu.

Web address: http://www.feinberg.northwestern.edu/transplant/Faculty/index.html.

The Immunology Program at the NCI-designated Moffitt Cancer Center in Tampa, Florida (USA) welcomes applications for NIH-funded Postdoctoral Fellowships to investigate fundamental mechanisms involved in anti-tumor immunity. Key areas of emphasis are (a) tumor and microenvironment cross-talk in controlling anti-tumor T cell responses and (b) development of novel adenovirus-based anti-tumor vaccines.

Key references include:

(1) Valenzuela JO et al. An essential requirement for PKC-theta in T cell alloreactivity and graft-versus-host-disease. J. Clin. Invest. 2009; 119(12): 3774-86.
(2) Hopewell EL et al. IKK-beta induced inflammation impacts the kinetics but not the magnitude of the immune response to a viral vector. Eur J Immunol. 2012; 42(3): 681-7.
(3) Hopewell EL et al. Lung tumor NF-kappa B signaling promotes T cell-mediated immune surveillance. J. Clin. Invest. Published online May 1 2013.

Preference will be given to individuals who have recently graduated with a Ph.D. degree in immunology or related field. Individuals with experience in immune assays, molecular biology, viral vaccines and mouse models will be preferred. Independence in initiating, conducting, evaluating and reporting of research studies is essential. Excellent verbal and written communication skills are required. Moffitt Cancer Center has state-of-the-art core facilities for cell therapy and immunotherapeutics, flow cytometry, proteomics, gene profiling, and transgenic mouse models.

To apply: Candidates should apply online at www.moffitt.org/careers to REQ ID 10910 and include a cover letter briefly summarizing research interests and career goals, CV, and contact information for three academic references.

Applications are invited for a postdoctoral position and several PhD studentships at the University of Missouri at Columbia. The major focus of our research is membrane fusion and cellular entry of enveloped RNA viruses as well as host innate immunity to viral infection, with particular interest in retroviruses, HCV and Ebola. Highly motivated individuals with strong background in virology and cell biology are particularly encouraged to apply. For the postdoctoral position, we are especially looking for candidates who had background and experience in lipid biophysics and live cell imaging. This candidate will be working on the mechanisms of newly identified cellular IFITM proteins that restrict Ebola virus, influenza viruses, and HIV-1.

To apply:Please send the cover letter, full CV, as well as the detailed contact information of three references to Dr. Shan-Lu Lu at liushan@missouri.edu.
Visit our website for more information:

http://bondlsc.missouri.edu/profile/view/liushan

A postdoctoral research position is available in the Department of Molecular Genetics, Institute of Molecular Medicine, Massey Cancer Center (MCC), Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298. MCC is a NCI designated cancer center with the state-of-the-art clinical and translational research facilities (http://www.massey.vcu.edu/). The postdoctoral fellow will have the opportunity to investigate the role of an inflammatory response and immunity in cancer or inflammatory diseases.

Qualifications required: A Ph.D. (or equivalent) in Immunology, Molecular and Cellular Biology, or related field. Candidates should have first-author research paper(s) published in a peer-reviewed journal. Previous experience working with mouse models of disease and flow cytometry is preferred. Responsible and highly self-motivated individuals are encouraged to apply.

To apply: Interested applicants should send their curriculum vitae, a statement of current and future research interests, and complete contact information of three references to Xiang-Yang (Shawn) Wang. Email address: xywang@vcu.edu; Website: http://www.medschool.vcu.edu/expertise/detail.html?ID=1544

Research lab in the Brain Tumor Research Center at Massachusetts General Hospital is seeking individuals at the postdoctoral level to join an effort dedicated to understanding the human immune response to brain tumors and examining novel immunotherapies in preclinical models. The lab focuses on identification of glioma-associated antigens and in developing immuno-monitoring strategies for patients with cancer vaccination protocols.

The ideal applicant should have a demonstrated track record of first-author publications from graduate work. The applicant must be highly-motivated, able to perform independent experiments, and have a strong background in tumor/xenograft surgical implantation in mouse model systems and in assays of immune function, including ELISA, ELISPOT, and flow cytometry. Molecular biology and histopathology support will be available. Applicants should have a Ph.D. or equivalent. Applications from women and representatives of minority groups are encouraged.

The Massachusetts General Hospital is an equal opportunity employer.

To apply: Interested candidates should forward curriculum vitae, along with names of three references and statement of research interest to: wcurry@partners.org

Department website: http://www.massgeneral.org/neurosurgery/research/researchlab.aspx?id=1465

An NIH/NIAID-funded postdoctoral position is available to study the immunobiology of negative vaccination in preclinical islet transplant models in the laboratory of Bernhard Hering at the Schulze Diabetes Institute at the University of Minnesota. The long-term objective of this project is the translational application of a tolerogenic negative vaccination protocol in the clinical settings of islet cell and solid organ transplantation. The successful candidate will closely interact with the PI as well as with co-PIs Drs. Steve Miller and Xunrong Luo at Northwestern University i) to optimize the ‘manufacturing’ of tolerogenic apoptotic donor cells as negative vaccines and ii) to investigate the mechanistic effects of preemptive negative vaccination on anti-donor cellular and humoral immunity. He/she will utilize an array of techniques (tissue culture, multi-parameter flow MLR, ELISPOTs, microarray and transcriptome analysis, Luminex, etc.) to determine the phenotype, frequency, proliferation, effector/regulatory functions, and memory generation of circulating and isolated graft infiltrating anti-donor B and T cells. This position will provide an opportunity to build a novel set of skills and expertise working at the interface of basic and translational transplantation immunology. Salary and benefits will be competitive.

Requirements: We are looking for a highly motivated and enthusiastic candidate with documented expertise in cellular immunology. Applicants must have a Ph.D. or M.D. preferably with no more than 5 year of postdoctoral experience. Proficiency in reading, writing, and speaking English and an outstanding publication record (at least one first-author research paper published in peer-reviewed journal) are required. Individuals with experience in nonhuman primate and/or human immunology are particularly encouraged to apply.

To apply: Interested applicants should submit 1) cover letter briefly describing your research accomplishments, interests, and career goals, 2) your CV, and 3) contact information of three references of your current and previous mentors, as one PDF by email to bhering@umn.edu. Please include “Postdoctoral Application” in the subject line.

The University of Minnesota is an equal opportunity educator and employer.

Contact: Bernhard J. Hering, M.D., Professor of Surgery and Medicine, McKnight Presidential Chair in Transplantation Science, Scientific Director, Schulze Diabetes Institute, Department of Surgery, University of Minnesota, 420 Delaware St. SE, Minneapolis, MN 55455; Phone: 612-626-5697; E-mail: bhering@umn.edu; Web Page: www.diabetes.umn.edu.

This position will investigate how estrogen controls pathogenic autoimmune T-cell responses in multiple sclerosis (MS), a demyelinating and neurodegenerative disease of the central nervous system. Our current research aims to elucidate estrogen-dependent regulatory mechanisms that inhibit EAE and the role of regulatory B-cells in this process. This position will conduct independent research, contributing to the writing of manuscripts and grant applications, preparing animal protocols and progress reports and collaborating with scientific colleagues from diverse disciplines.

Minimum Qualifications:

• PhD
• Expertise in immunological methods, including an in-depth knowledge of FACS analysis (minimum 2-5 years experience) as well as cellular and molecular techniques to evaluate both pathogenic and regulatory cell types

Oregon Health & Science University values a diverse and culturally competent workforce. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. OHSU provides reasonable accommodations for applicants with disabilities. We are proud to be an equal opportunity, affirmative action organization.

To apply: Interested candidates should send CV and 3 recommendation letters to Melissa Barber at barberm@ohsu.edu.

Our laboratory in the Department of Pathology at Brigham and Women’s Hospital and Harvard Medical School in Boston, MA, studies the immunobiology of innate T cells. We are particularly interested in the mechanisms that activate CD1d-restricted Natural Killer T (NKT) cells and their role and function during inflammation and microbial infection. Current projects in the lab are focused on understanding the recognition of CD1d-presented microbial and self-lipid antigens and the regulation of their expression, the mechanisms of activation of NKT cells, and the function of NKT cells during inflammation and infection. We are studying both invariant (type I) and diverse (type II) NKT cells using cutting edge molecular biology, cellular immunology, and lipid chemistry techniques, as well as genetically modified in vivo mouse models, and collaborate extensively with local, national and international research groups. For more information on the Brigl lab, please visit: http://brigl.bwh.harvard.edu/.

This position provides an opportunity to build a highly novel set of skills and expertise using cutting edge technologies, and to work in a highly dynamic research environment. The lab and department are in close proximity to the rich and innovative research environment within the Harvard and wider Boston research communities.

The successful applicant is highly self-motivated, able to work independently and in collaborative relationships within the lab and with our outside collaborators. Applicants must have a Ph.D. or M.D. degree that was awarded within the last three years in the area of immunology, and experience working with mouse models. Stipends will be in accordance with NIH and institutional guidelines.

To apply: If you are interested, please submit a CV; a brief description of your background, research accomplishments, interests, and career goals; contact information (email address and phone number) of three references who are familiar with your work; and pdfs of any relevant publications to: mbrigl@rics.bwh.harvard.edu.

Lymphangioleiomyomatosis (LAM) is a rare, progressive lung disease that affects women almost exclusively, particularly during childbearing years. Characterized by an abnormal growth of smooth muscle cells which invade lung tissues resulting in cystic destruction of the lung. This in turn blocks airflow and limits the delivery of oxygen to the body. At present there is no cure for LAM, and few treatment options exist.

Dr. Thomas Lowder, an assistant professor in Health and Human Performance, will soon begin a study to investigate the benefits of a supervised aerobic exercise-training intervention in LAM patients. This study will be performed in conjunction with the University of Texas Health Science Center.

Dr. Lowder has several openings in his laboratory for motivated graduate students who wish to work closely with the investigative team and with patients. Experience in pulmonary function is desirable but not required.

To apply: If you are interested in learning more, please contact Dr. Lowder by e-mail at twlowder@uh.edu or by phone at (713) 743-4187.

Postdoctoral position at UH to isolate and characterize antibodies from primary B cells in collaboration with M.D. Anderson Cancer Center, funded by the NIH. The successful candidate will work on a multi-disciplinary team involving engineers and clinicians. The candidate will be expected to devise or modify immunological methods to achieve results and publish papers in research journals. Presentation at national meetings and career-development will be encouraged.

Strong communication skills (written/verbal) in English are required.

Education/Experience: A Ph.D. or MD/Ph.D. degree in the field of antibody discovery/engineering is required. Experience working with B cells and single-cell cloning is considered an advantage.

Timing: Immediate

To apply: Please send CV and list of three references via email to nvaradarajan@uh.edu.

This position is responsible for assisting research design as well as conducting independent projects. We are looking for a highly motivated individual to study the mechanisms of peripheral T-cell activation and tolerance in response to alloantigen and tumor antigen after allogeneic bone marrow transplantation. These basic and translational researches are primarily conducted in murine models in vitro and in vivo, and require techniques in Immunology, Molecular Biology and Biochemistry.

A strong background in immunology is preferred. Ability in initiating, conducting, evaluating and reporting of research studies is essential. Experience with tissue culture, flow cytometry, procedures on mice and standard molecular biologic methodologies is desirable. Excellent verbal and written communication skills are required. Candidates should include a cover letter briefly summarizing research interests and career goals, CV, and contact information for three academic reference. Opportunities for advancement based on individual credentials.

Contact: Morgan Furr, MUSC College of Medicine, Dean’s Office, HR Center of Expertise, 96 Jonathan Lucas Street, MSC617, Room 231a CPP, Charleston, SC 29425-6170; furr@musc.edu; (P): 843.876.2257; (F): 843-876-1145.

To apply: Interested applicants should apply here: www.jobs.musc.edu/applicants/Central?quickFind=190500

Department website: http://academicdepartments.musc.edu/immunology

Interested candidates are invited to apply for a postdoctoral position in immunology, with an emphasis on microevolution of immune function in natural populations. With funding from the Howard Hughes Medical Institute (HHMI), Dr. Dan Bolnick’s research group (at the University of Texas at Austin) is investigating the immunological and genetic basis of adaptation to diverse communities of helminth parasites of the three-spine stickleback (Gasterosteus aculeatus). The stickleback has long been a major model organism in evolutionary genetics, ecology and behavior, and the recent publication of many stickleback genome sequences and development of transgenic methods offers new opportunities. The Bolnick lab is searching for an immunologist for a two year postdoctoral position to develop new methods for studying immune function in this model organism. The postdoc can help determine the nature of these methods. The postdoc will help apply these tools to understand vertebrate resistance or tolerance of parasites, and to study within-population variation and between-population divergence in immune function. The postdoctoral researcher will be responsible for conducting laboratory research, data analysis, and manuscript preparation. Involvement with field research is an option.

Candidates should have a Ph.D. in immunology or a related field, and a proven record of research in immunology, evidenced by successful publishing in scientific journals. Good communication skills are essential.

The postdoctoral position comes with a competitive salary, as well as health insurance and retirement investment benefits. The position’s start date is negotiable. The position’s duration is approximately 2 years (through August 2015), and might be extended if additional funding is acquired. The postdoc will be an employee of the Howard Hughes Medical Institute, with an additional appointment at the University of Texas at Austin.

To apply: To apply for the postdoctoral position, please send a CV, pdfs of at least 2 relevant papers, and a cover letter summarizing your qualifications. In the cover letter, you are encouraged to include a brief proposal of the kinds of immunological or genetic tools you could develop for stickleback, and their relevance for understanding host-parasite interactions and/or coevolution. Please provide contact information for at least two references.

Applications will be reviewed starting April 15, but the position will remain open until filled by a suitable candidate. Please contact Dr. Daniel Bolnick (danbolnick@austin.utexas.edu) for inquiries.

The Bolnick lab’s research focuses on evolutionary ecology of trait variation within populations, including variation in diet, courtship traits, and immune function. More information on research in the lab can be found at https://webspace.utexas.edu/dib73/Bolnicklab/Bolnicklab.htm?uniq=5ptsas.

More information on the Section of Integrative Biology can be found at http://www.biosci.utexas.edu/ib/.

HHMI and the University of Texas are Affirmative Action/Equal Opportunity Employers.

A Postdoctoral Research Associate position in Immunology is available in the laboratory of Dr. Karen Taraszka Hastings at the University of Arizona College of Medicine Phoenix.

Our laboratory focuses on the role of antigen presentation in the generation of anti-tumor immune responses and autoimmunity, using mouse models, cell culture systems, and patient samples. Ongoing projects involve the role of the MHC class II processing pathway in the development of T cell tolerance in mouse models of melanoma and autoimmune vitiligo and the evaluation of MHC class II-restricted presentation in human melanoma and lymphoma.

The University of Arizona College of Medicine Phoenix is at the center of tremendous biomedical growth that will take place in Phoenix in the coming years. My laboratory is located in a new state-of-the-art research building with core equipment facilities such as a BD LSRII flow cytometer. The atmosphere is highly collaborative, and the laboratory interacts with local researchers at the Mayo Clinic Scottsdale and the University of Arizona in Tucson, as well as scientists at the University of California San Francisco and Yale University.

For further information, please visit http://bms.med.arizona.edu/faculty/karen-taraszka-hastings-md-phd

To apply: Go to https://www.uacareertrack.com/, click on Search Postings, enter Job Number 51931, click on View Job Details/Apply.

One postdoctoral position is available in the laboratory of Shikhar Mehrotra, Ph.D., in the Department of Surgery, Microbiology & Immunology at the Medical University of South Carolina (MUSC), Charleston, SC. The overall focus of our lab is to develop novel strategies to improve T cell persistence for adoptive therapy of melanoma, by better understanding of T cell signaling and metabolic mechanisms regulating T cell differentiation.

Relevant experience with animal research, contemporary molecular and immunological techniques, and primary cell culture, immunological techniques and flow cytometry are highly desirable. Candidate should be highly motivated, creative, with strong work ethic and ability to work independently as well as in collaborative research efforts. Excellent verbal and written communication skills are required. Furthermore, there will be possibility for career advancement and the pursuit of an independent career path within the Department. Dr. Mehrotra’s laboratory is part of the Surgical Oncology Group, the Cancer Immunology Program, and the Hollings Cancer Center, and thus, has access to a wide range of cutting-edge core resources on campus. The Hollings Cancer Center is an NCI-designated cancer center, indicative of the strong institutional commitment toward human immunology and translational research. The Medical University of South Carolina (MUSC) is located in Charleston, SC, a beautiful and historic city on the Atlantic coast. Additional information can be found at the MUSC website: http://academicdepartments.musc.edu/surgery/divisions/surgonc/faculty/mehrotra.htm

Candidates should have a Ph.D. and/or M.D. with first-author research paper(s) published in a peer-reviewed journal.

To apply: Please send: i) a cover letter briefly summarizing your research interests and career goals, ii) your CV, and ii) a list of 3 references, as PDF or word documents to mehrotr@musc.edu.

Shikhar Mehrotra, Ph.D., Associate Professor, Department of Surgery, Microbiology & Immunology, Medical University of South Carolina, 86 Jonathan Lucas Street, HO-512H, Charleston, SC 29425; Phone: 843-792-9195; E-mail: mehrotr@musc.edu.

We are seeking a highly motivated postdoctoral fellow to join our research program: Sphingolipids’ modulation of host defense and immunity to the infections of influenza virus and LCMV. The research can provide a basis for development of a novel molecular immunotherapy or cytotherapeutics to treat diseases caused by virus infections. Candidates that have experience using mouse models in the field of viral immunology are preferred.

To apply: Applicants should send a CV to Dr. Hahm via e-mail (E-mail address: hahmb@health.missouri.edu).

Bumsuk Hahm, Ph.D., Departments of Surgery and Molecular Microbiology and Immunology, Center for Cellular and Molecular Immunology; Virology Center; School of Medicine, University of Missouri-Columbia, One Hospital Dr., Columbia MO 65212; http://medicine.missouri.edu/mmi/hahm-b.html.

The Feeney Laboratory in the Division of Experimental Medicine at UCSF is seeking highly motivated postdoctoral research fellows to design and conduct research related to the cellular immune response to malaria, with a focus on immunoregulatory pathways.

The successful candidate will pursue patient-oriented immunology research based on international collaborations in Uganda. The mission of the Division of Experimental Medicine is to understand the human immune system so that lifesaving therapies and vaccines can be developed to protect against chronic infectious diseases of global importance, and to establish a training environment that fosters patient-oriented research in the U.S. and abroad.

Candidates should possess a Ph.D. and/or M.D. and have a strong background in immunology or infectious disease research. Experience with immunologic techniques including multiparametric flow cytometry and/or molecular biology techniques including RT-PCR is a plus. Excellent communication and writing skills are essential. Foreign candidates will be considered if they are highly proficient in English, are able to travel to San Francisco to interview, and have published in high impact journals in the field.

Candidates should possess a Ph.D. and/or M.D. and have a strong background in immunology or infectious disease research. Experience with immunologic techniques including multiparametric flow cytometry and/or molecular biology techniques including RT-PCR is a plus. Excellent communication and writing skills are essential. Foreign candidates will be considered if they are highly proficient in English, are able to travel to San Francisco to interview, and have published in high impact journals in the field.

To apply: Interested candidates should email a cover letter, CV, and 3 references to Dr. Margaret Feeney, Associate Professor, Division of Experimental Medicine, UCSF (feeneylabucsf@gmail.com).

We are seeking a highly talented, innovative and enthusiastic postdoctoral researcher with a PhD in biological science. Our work is focused on the immunological basis of neuropsychiatric disorders, in particular major depressive disorder and bipolar disorder. The research will be conducted at the Laureate Institute for Brain Research (LIBR) as well as the Integrative Immunology Center at the University of Oklahoma, Tulsa in the labs of Jonathan Savitz (LIBR) and Kent Teague (OU).

Qualifications required: A Ph.D. in immunology, molecular biology or closely-related field. Experience with qPCR, FACS, and ELISA and/or other cytokine measurements will be considered a distinct advantage. The candidate is expected to actively contribute his or her own ideas and proposals and independently formulate scientific questions and design experiments. Applicants should have a consistently excellent academic and publication record. The position is for an initial 12-month period, with the possibility of extension for an additional 24 months.

To apply: Applicants should email their CV and the contact information of three references (including their present and previous mentors) to:

Jonathan Savitz, Ph.D., Assistant Professor, Laureate Institute for Brain Research, Tulsa OK 74136; E-mail: jonathansavitz@hotmail.com

A postdoctoral position is available immediately in the laboratory of Dr. Tian Wang at the University of Texas Medical Branch (UTMB) to study immune response and viral pathogenesis during flavivirus infection.

UTMB is located on Galveston Island, about 50 miles south of Houston, TX and has state -of-the-art BSL-2, BSL-3 facilities to study emerging infectious pathogens.

The preferred candidate should hold either a Ph.D. or M.D. degree or equivalent degree within the last 2 years, with a demonstrable publication record in immunology and animal (mouse) experiments.

To apply: Candidates with a strong desire and commitment to conduct research in viral immunology should submit their CV and names of three references to: Tian Wang, Ph.D., Department of Microbiology & Immunology, Department of Pathology, Keiller 3.118B, University of Texas Medical Branch, Galveston, TX 77555, Office: (409) 772-3146; E-mail: ti1wang@utmb.edu. (Preferred)

A post-doctoral position is open for an energetic, highly motivated Ph.D., M.D., or D.V.M. scientist in a NIH-funded startup laboratory at the University of North Carolina, Chapel Hill. Our laboratory is interested in studying the genetics of autoimmunity in both humans and animal models. In particular, we are interested in studying the role of the Autoimmune Regulator (Aire) gene in preventing organ-specific autoimmunity. Our highly translational laboratory is affiliated with the Departments of Microbiology/Immunology and Pediatrics, which allows for ample opportunity to bridge the bench and bedside. Experience in immunology, genetics, molecular biology and history of productivity is required.

To apply: Please email CV and 3 references to: masu@email.unc.edu.

Expand the horizons of medical knowledge.

Cedars-Sinai is one of the most dynamic and highly renowned medical centers in the world and is the largest academic medical center in the western United States. The Burns and Allen Research Institute has one of the largest state-of-the-art clinical and translational research facilities of any private hospital in the nation. As a major community medical center and tertiary referral center, Cedars-Sinai offers an environment of unparalleled opportunity for translational studies. If you are committed to working at the leading edge of medical discovery, we invite you to join our world-class research organization.

Innate Immunity and Host-Pathogen Interaction - A postdoctoral position is available at the Infectious and Immunological Diseases Research Center (IIDRC) at Cedars-Sinai Medical Center, Department of Biomedical Sciences and the Department of Pediatrics/Division of Infectious Diseases and Immunology.

Candidate must be a permanent U.S. Resident.

This is an NIH-funded position to investigate Innate Immunity and Host Pathogen interaction, inflammation and mucosal immunity. We investigate the role of Toll-Like Receptors, NLRs, NLRP3/IL1, IL17 pathways, apoptosis, autophagy and the microbiome in various mouse models of heart, lung inflammation including asthma and vasculitis models.

The position is for three years and offers a competitive salary based on the candidate’s qualifications.

To apply: Please submit your curriculum vitae, a brief summary of research experience, and goals, and names of three references with contact information to Moshe Arditi, M.D. - moshe.arditi@cshs.org.

Qualifications/Requirements/Preferences: Education Certifications/Licensure Experience

Experience: Independently worked on research projects designed by a mentor (typically the PI) within area of specialization. Acquired thorough technical and theoretical knowledge of research project and objectives during doctoral or postdoctoral appointment. Demonstrated aptitude to perform experimental protocols and procedures in mouse models including detailed data collection, and analysis and operation and maintenance of specialized equipment. Knowledge of safety standards and maintenance of specialized equipment.

Educational Requirements: Candidates should have a Ph.D. degree in cellular molecular biology or immunology with a strong background and experience in innate immunity mucosal immunology and mouse models.

Cedars-Sinai is an Equal Opportunity Employer that welcomes and encourages diversity in the workplace.

A postdoctoral position is available in the laboratory of Dr. Balaji Manicassamy in the area of influenza virus-host interactions. The laboratory focuses on understanding the differences in host responses to seasonal influenza virus and highly pathogenic avian influenza viruses, using recombinant influenza GFP reporter viruses and multicolor flow cytometry to follow infection and host responses.

The goal of the lab is to understand the contributions of viral cell tropism to pathogenesis and modulation of host responses. The ideal candidate will have a strong background in immunology with expertise in cellular immunology.

Experience in working with viruses is not required but is preferred. Recent recipients of the Ph.D. are encouraged to apply.

To apply: Please send your application including CV, summary of past accomplishments, research interests and contact information of three references to Balaji Manicassamy, Ph.D., Assistant Professor, Department of Microbiology, The University of Chicago, 920 E 58th Street, CLSC 711B, Chicago, IL-60615 or email to bmanicassamy@bsd.uchicago.edu

A postdoctoral position is available in the laboratory of Chrystal Paulos in the Department of Microbiology and Immunology and Department of Surgery at the Hollings Cancer Center, Medical University of South Carolina, Charleston, SC.

Successful candidates should have a PhD, MD or MD/PhD degree with a strong background in Molecular Biology and Immunology. Our main project focuses on molecular and cellular mechanisms underling how cotimulatory molecules modulate genetic engineering of T cell subsets to recognize advanced human tumors. We seek to improve the quality and long-lived memory phenotype of engineered T cells via understanding how costimulatory molecules, cytokines and novel pharmaceutics regulate their functional and transcriptional fate. (C.M. Paulos,et.al., ICOS critically regulates the expansion and function of inflammatory human Th17 cells. Science TM. 2 (55):55ra78 (2010). *Accompanying Perspective and Science Highlight).

Our lab focuses on developing novel T-cell immunotherapies for patients with advanced cancer. Our strategy is based on the use of clinically relevant mouse models and ex-vivo assays with human T cells to ultimately develop human clinical trials that effectively harness the patient's own immune system to kill cancer. We study new ways to improve adoptive cell transfer (ACT) therapy, which involves the removal of T-cells from the patient, their expansion/manipulation ex-vivo, followed by their infusion back into the patient preconditioned with lymphodepletion.

In addition to studying the role of tumor-specific T cell subsets, we also investigate the mechanisms underlying the effectiveness of lymphodepletion prior to ACT therapy and use this valuable information to design safer and more effective approaches to treat patients with cancer. Our discoveries have relevance in the design of T-cell based therapies for HIV and autoimmune disease. Moreover, we explore how the microbiome shapes tumor immunity in our world-renowned gnobiotic animal facility (C.M. Paulos,et.al, Toll-like receptors in tumor immunotherapy. Clinical Cancer Research. 15; 13(18 pt. 1):5280-9 (2007). C.M. Paulos,et.al., Microbial translocation augments the function of self/tumor-specific CD8+ T cells via TLR4 signaling. The Journal of Clinical Investigation. 117(8):2197-204 (2007). Please see our webpage for additional information: (http://academicdepartments.musc.edu/immunology/Faculty/paulos.html).

We are looking for motivated, creative and interactive scientists within very early stages of their PhD or MD/PhD degree. Qualified applicants should have first-author research paper(s) published in peer-reviewed journal. The ideal candidates should also have first-hand experience in cell culture and related biochemical techniques (particularly real-time PCR, Western blots, gene engineering, vector and plasmid design, etc.). Candidates should also have experience in handling mice, conducting and analyzing flow cytometry and ELISA. The ability to design, evaluate and report research is required. Excellent verbal and written communication skills are required. We seek exceptionally motivated postdoctoral fellows to share our passion in research that are team players and work well together.

To apply: Interested applicants are encouraged to submit an application by email to paulos@musc.edu, including a cover letter outlining research interests, CV, and the contact information of three referees.

The Hollings Cancer Center is an NCI-designated cancer center, indicative of the strong institutional commitment toward human immunology and translational research. The center also has access to a wide range of cutting-edge core resources on campus. We have close collaborations with members of the Department of Microbiology & Immunology, Department of Surgery, and the entire scientific community, which provides a unique opportunity for the translation of basic tumor immunology into potent treatments for patients with cancer.

The Medical University of South Carolina is located in the heart of Charleston, SC, a beautiful and historic city on the Atlantic coast. Charleston has elegant beaches, has great weather for a wide range of outdoor activities, and is a culturally rich city with food, art, theater, dance, and music festivals.

MUSC is an equal opportunity employer supporting workplace diversity M/F/V/D.

NIH-funded POSTDOCTORAL POSITION available at the F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute (IBIRI)/ Departments of Biomedical Science (Research Division of Immunology)/ Medicine at the Cedars-Sinai Medical Center in Los Angeles to study molecular regulation of T cell effector function in the intestinal mucosa.

Current areas of specific interest include the role of a transcriptional repressor in preventing mucosal T cell hyper responsiveness (Nat Immunol. 2006 May;7(5):457-65.; . Exp Med. 2008 Sep 1;205(9):1959-65; J. Immunol., 189(12): 5682-93, 2012) and identification of new pathways regulating mucosal T cell function in humans.

Candidates should have a demonstrated record of significant scientific accomplishment at the graduate or postdoctoral level, and a solid background in immunology and molecular biology. Specialty background in mucosal immunology, in vivo mice models preferred but not absolutely required.

To apply: To apply send CV and contact list (emails, phone #s and names) of three references to Gislaine A. Martins, Ph.D., martinsg@csmc.edu

Research in Dr. Piliponsky’s lab is focused on the regulation of the innate immune response to bacterial infections; specifically, interest in the ability of mast cells and mast cell specific proteases to down-regulate mediators that contribute to inflammation through degradation. Piliponsky lab uses mass spectrometry analysis, in collaboration with other researchers at the University of Washington, to identify targets of mast cell proteases. Piliponsky lab uses biochemical and molecular biology approaches in combination with mass spectrometry to validate targets of mast cell proteases. They employ mast cell-deficient mice, mice deficient in mast cell specific proteases, and immune reconstitution of mice with modified hematopoietic stem cells to investigate the contribution of these targets and their down-regulation by mast cell proteases to inflammation.

The post-doctoral hired for the position will use an array of cellular and molecular approaches (ELISA, cell isolation, flow cytometry, histology, microarray and transcriptome analysis, qPCR, bacterial propagation and protein isolation; as well as, animal models of infection). They will also be expected to formulate, execute, and communicate research projects.

Qualifications: Requirements include a recent PhD and/or MD in Immunology or other cell biology- related fields (preferably including immunology training). PhDs graduated within two years are particularly encouraged to apply. Successful candidates should be highly motivated with an outstanding publication record (at least one first-author research paper published in peer-reviewed international journal) and work ethic. Candidates are required to have a strong research background in cellular immunology, biochemistry, and mouse models of bacterial infections; as well as, excellent written and oral communication skills in English.

To apply: Please send: 1) cover letter briefly describing your research accomplishments, interests and career goals, 2) your CV, and 3) a list of three references of your current and previous mentors, by email to adrian.piliponsky@seattlechildrens.org.

Adrian M. Piliponsky, Ph.D., Assistant Professor, Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Department of Pediatrics, University of Washington, Seattle; www.seattlechildrens.org

A postdoctoral position is immediately available in the Department of Immunology at Roswell Park Cancer Institute to study immune reconstitution after hematopoietic stem cell transplantation. The postdoctoral fellow will have the opportunity to study cancer and transplant patients and mouse models in order to delineate the molecular and cellular mechanisms that mediate graft-versus-host disease and graft-versus-tumor effect. The initial project will focus on investigating T cell differentiation, function, and regulation in the setting of allogeneic hematopoietic cell transplantation.

Requirements: Highly motivated PhD or MD/PhD students who graduated within three years are encouraged to apply. A solid background and working experience in the following areas are highly desired:

1. Immunology
2. Mouse models of cancer
3. Gene targeting and transgenics
4. Bioinformatics

Preferred candidates should be fluent in English.

To apply: Please e-mail an application including a cover letter describing current research, future interests, expected start date, and CV, selected publications, names and contact information of three references to:

Xuefang Cao, Ph.D., Assistant Professor, Department of Immunology, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263; Tel: (716) 845-3963; Fax: (716) 845-1322; Email: Xuefang.Cao@RoswellPark.org; Web: http://www.roswellpark.edu/xuefang-cao; Publication: http://www.ncbi.nlm.nih.gov/pubmed/?term=xuefang+cao

A postdoctoral research position in mucosal immunology and microbiome is open in the Department of Medicine, at the University of Colorado, Anschutz Medical Campus, Denver, CO. Our lab studies allogeneic immune responses that develop following bone marrow transplantation, including graft-versus-host disease, tolerance, and immune reconstitution. We are particularly interested the interaction of the host and commensal microbiota in mediating disease under these settings, particularly focusing on identifying relevant microbiota species that cause disease and dissecting the innate and adaptive immunity pathways which mediate this process.

The position is intended for exceptional candidates with a Ph.D., or M.D/PhD, who has excellent graduate training and a record of publications in immunology. Foreign candidates are considered if they are highly proficient in English, are able to travel to Colorado to interview, and have published in high impact journals in the field. Experience in mucosal and T cell immunology, molecular biology, genomics/bioinformatics/metagenomics, and in vivo mouse models is highly desired.

To apply: Interested applicants should email their curriculum vitae, a statement of current and future research interests, and complete contact information of three references to vu.h2.nguyen@ucdenver.edu.

A postdoctoral position is available starting in July 2013 in the laboratory of Dr. Pamela Guerrerio at Johns Hopkins University School of Medicine. Research project will involve translational studies aimed at understanding the mechanisms of allergic disease and mucosal tolerance. A background in immunology and standard laboratory techniques (tissue culture, flow cytometry, ELISAs, PCR, etc) is required. Candidates must have a Ph.D. and/or M.D., have excellent written and oral communication skills, and wish to pursue a career in academic research.

To apply: Interested candidates should send their curriculum vitae, statement of career goals/interests, names of three references, and their contact information to pguerrerio@jhmi.edu.

This is an NIH-funded T32 training grant position and, as such, only U.S. citizens or permanent residents are eligible.

A postdoctoral position is available in the Department of Urology at Northwestern University to study T cell mechanisms in prostatitis and chronic pelvic pain. The individual working in this position is expected to be a trained immunologist with expertise in human and mouse cellular immunology. Ongoing studies utilize clinical samples and disease models to elucidate Th1/Th17 immune mechanisms and the role of regulatory T cells in prostatitis and chronic pelvic pain. Applicants must have an MD and/or DVM and/or PhD degree with a record of innovative scientific accomplishment in graduate and/or post-graduate studies, as evidenced by the applicant’s PhD thesis and/or by first authorships in peer-reviewed journals. Northwestern University is one of the top-ranked universities in the country with a highly interactive scientific environment. The Feinberg School of Medicine (feinberg.northwestern.edu) is known for its pioneering research and is located in the heart of downtown Chicago. Salary and benefits will be competitive. Please send your CV and contact information for three references to Dr. Praveen Thumbikat (thumbikat@northwestern.edu) if you are an interested candidate for this position. Applications will be accepted till the position is filled.

To apply: Please send your CV and contact information for three references to Dr. Praveen Thumbikat (thumbikat@northwestern.edu) if you are an interested candidate for this position. Applications will be accepted till the position is filled.