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Saturday, April 5: 5:00 PM; San Diego Convention Center, Room 20 B/C/D
Olivera (Olja) J. Finn, University of Pittsburgh School of
Medicine, AAI President, Immunologic weapons acquired early in life
win battles with cancer late in life
Presentation of the AAI Lifetime Achievement Award Chair: Olivera (Olja) J. Finn, University of Pittsburgh School of Medicine, AAI President
Award recipient:
Robert R. Rich,
M.D., University of Alabama at Birmingham School of Medicine
Presidential Symposium
Taking Care of Immunology around the World Tuesday, April 8: 2:30 PM, San Diego Convention Center, Room 20 B/C/D
Chair: Olivera (Olja) J. Finn, University of Pittsburgh School
of Medicine, AAI President Xuetao Cao, Second Military Medical University Shanghai, President, Chinese Society of Immunology, Stromal microenvironment, regulatory dendritic cells, and regulation of immune response Cornelis J. M. Melief, Leiden University Medical Center, President, Dutch Society for Immunology, Immunotherapy of established lesions induced by high risk papilloma virus Ljiljana Sofronic-Milosavljevic, Institute for the Application of Nuclear Energy (INEP), Belgrade, Serbia, President, Immunological Society of Serbia, Taming of autoimmunity - Trichinella, worm under host-parasite contract Adrian C. Hayday, Guy's Hospital, General Secretary, British Society for Immunology, Immunosurveillance: molecular conversations between epithelial cells and the immune system Hermann J. Ziltener, The Biomedical Research Center, University of British Columbia, President, Canadian Society for Immunology, New roles for an old acquaintance: function of PSGL-1 in thymic homeostasis and a novel mechanism of naive T cell homing
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San Diego Convention Center, Room 20 B/C/D
Chair:
John G. Monroe, AAI Program
Chair, Genentech, Inc. Kathryn Calame, Columbia University
Blimp-1 and the Regulation of Lymphocyte Function
Monday, April 7: 5:00 PM San Diego Convention Center, Room 20 B/C/D Chair: John G. Monroe, AAI Program Chair, Genentech, Inc.
Marc K. Jenkins, University of Minnesota Medical School On the Trail of Epitope-Specific Naive Helper T Cells in Normal Individuals
Tuesday, April 8: 5:00 PM San Diego Convention Center, Room 20 B/C/D Chair: John G. Monroe, AAI Program Chair, Genentech, Inc.
Harinder Singh, HHMI University of Chicago
Gene Regulatory Networks Orchestrating Cell Fates in the Immune
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Sunday, April 6, 2008 – 8:00 AM
Major Symposium A: Genetics of Autoimmunity
Chairs: Betty A. Diamond, Feinstein Institute for Medical Research;
Linda S. Wicker, Cambridge Institute for Medical Research Peter K. Gregersen, North Shore University Hospital, Rheumatoid arthritis in the genomic era: cracking the code for clues to autoimmune pathogenesis Gerald T. Nepom, Benaroya Research Institute, Probing for disease susceptibility Linda S. Wicker, Cambridge Institute for Medical Research, The IL-2/CD25 pathway determines susceptibility to type I diabetes in humans and NOD mice William M. Ridgway, University of Pittsburgh, Genetic control of autoimmune liver disease in NOD congenic mice Betty A. Diamond, Feinstein Institute for Medical Research, BCR signaling strength determines predisposition to autoantibody production
Major Symposium B: Microenvironmental Influence on Immune Function
Chairs:
Jason G. Cyster, University of California, San Francisco; Peter
J. Lane, University of Birmingham Jonathan W. Yewdell, NIAID, NIH, Getting real: intravital imaging of antiviral CD8+ T cell priming and effector function Shannon J. Turley, Dana Farber Cancer Institute, Harvard Medical School, Antigen presentation by lymph node stromal cells and dendritic cells Melody A. Swartz, Swiss Federal Institute of Technology, Lausanne, Mechanisms of dendritic cell homing towards and entry into lymphatic vessels Ellen A. Robey, University of California, Berkeley, Imaging host-pathogen interactions in a Toxoplasma gondii infection model
Jason G. Cyster, University of California, San Francisco,
Requirements for lymphocyte egress from lymphoid organs
Monday, April 7, 2008 – 8:00 AM
Major Symposium C: TNF Family Members in Inflammation, Autoimmunity,
and Cancer
Chairs: Michael Croft, La Jolla Institute for Allergy and
Immunology; Tania H. Watts, University of Toronto Michael Croft, La Jolla Institute for Allergy and Immunology, OX40 and the decision between tolerance and immunity Richard M. Siegel, NIAMS, NIH, TL1A/DR3 interactions in inflammation and autoimmunity Carlo Riccardi, University of Perugia, GITR/GITRL system in the regulation of the immune/inflammatory response
Carl F. Ware, La Jolla Institute for Allergy and Immunology,
The LIGHT and DARC sides of a TNF receptor
Major Symposium D: Organ-Specific Regulation of Innate Immunity
Chairs: Eyal Raz, University of California, San Diego; Robert
L. Modlin, University of California, Los Angeles Bali Pulendran, Emory University, Differences between gut and splenic macrophages Robert L. Modlin, University of California, Los Angeles, A TLR-induced vitamin D-dependent antimicrobial mechanism in microbial infection in skin and the lung Dean Sheppard, University of California, San Francisco, Organ-specific regulation of Th-17 and Treg induction through TGF-b activation by dendritic cells Andrea M. Cooper, Trudeau Institute, The protective vs. the pathogenic role of the innate cytokine IL-23 in the lung Jongdae Lee, University of California, San Diego, The uniqueness of TLR signaling in colonic epithelial cells
Bruce A. Beutler, The Scripps Research Institute,
Organ-specific innate immunity as dissected by ENU mutagenesis
Tuesday, April 8, 2008 – 8:00 AM
Major Symposium E: Managing B Cell Lifespan and Lifestyle with BAFF
Family Interactions
Chairs: Michael P. Cancro, University of Pennsylvania School of
Medicine; Fabienne Mackay, Garvan Institute of Medical Research Fabienne Mackay, Garvan Institute of Medical Research, The role of BAFF in autoimmunity is T cell-independent but requires MyD88 Signaling Andrea Cerutti, Weill Medical College of Cornell University, BAFF and APRIL: key innate regulators of immunoglobulin heavy chain class switching Jennifer Anolik, University of Rochester Medical Center, Determinants of B cell reconstitution after B cell depletion therapy in human autoimmune disease Jane A. Gross, Zymogenetics, Inc., B cell-targeting therapies for autoimmune diseases: are they all the same? Richard J. Bram, Mayo Clinic, TACI: Signaling and function in the immune system
Chairs: Yasmine Belkaid, NIAID, NIH; E. John Wherry, The
Wistar Institute Yasmine Belkaid, NIAID, NIH, Regulatory T cells during parasitic infections
JoAnne L. Flynn, University of Pittsburgh, Regulation of
immune responses in tuberculosis Markus Mohrs, Trudeau Institute, Tracking cytokine responses to infection
Christian Munz, Rockefeller University, Innate and adaptive
immunity through autophagy
Wednesday, April 9, 2008 – 8:00 AM
Major Symposium G: Control of Effector and Memory T Cell Fate
Chairs: Donna L. Farber, University of Maryland at Baltimore;
Steven L. Reiner, University of Pennsylvania Steven L. Reiner, Abramson Family Cancer Research Institute, University of Pennsylvania, Shaping the fate of T cells in response to infection Eric G. Pamer, Memorial Sloan-Kettering Cancer Center, Trafficking and differentiation of CD4 T cells during respiratory infections Richard M. Locksley, University of California, San Francisco, Initiating type-2 immunity Ananda W. Goldrath, University of California, San Diego, Making CD8 memory
Robert A. Seder, Vaccine Research Center, NIAID, NIH, The
quality of T cell responses determines protection
Major Symposium H: Can Basic Advances
in Immunology Generate Effective Cancer Therapies?
Chairs: Robert D. Schreiber, Washington University School of
Medicine; Carl H. June, University of Pennsylvania Glenn Dranoff, Dana Farber Cancer Institute, Harvard Medical School, The interplay of tumor immunity and inflammation Philip D. Greenberg, University of Washington, Generating and maintaining function of T cells with high avidity for tumor antigens Carl H. June, University of Pennsylvania, Adoptive transfer of lentiviral engineered T cells for cancer immunogene therapy James P. Allison, Memorial Sloan-Kettering Cancer Center, Immune responses to early vs. late stages of cancer
Cornelia Trimble, Johns Hopkins Medical Institutions,
Targeting adaptive immune responses for HPV disease |
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AAI Awards being presented at AAI's 95th Annual Meeting, in conjunction
with Experimental Biology 2008:
Details on awards presentations appear in the following two sections. |
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Supported through an unrestricted grant from the Dana Foundation Sunday, April 6: 3:15 PM; San Diego Convention Center, Room 20 B/C/D Chair: Olivera (Olja) J. Finn, University of Pittsburgh School of Medicine, AAI President
Award Recipient: James
P. Allison, HHMI, Memorial
Sloan-Kettering Cancer Center, Immune checkpoint blockade in cancer
therapy
AAI-BD Biosciences Investigator Award & Lecture Supported through an unrestricted educational grant from BD Biosciences Monday, April 7: 2:30 PM, San Diego Convention Center, Room 20 B/C/D Chairs: Olivera (Olja) J. Finn, University of Pittsburgh School of Medicine, AAI President; Robert Balderas, Vice President of Research and Development, BD Biosciences-Pharmingen, San Diego, CA
Award Recipient: Pamela L. Schwartzberg, National Human Genome
Research Institute, NIH, Integrating T cell signals: lessons from
mouse models and primary immune disorders
AAI-Invitrogen Meritorious Career Award and Lecture Supported by an unrestricted educational grant from Invitrogen Corporation Monday, April 7: 3:30 PM, San Diego Convention Center, Room 20 B/C/D Chair: Olivera (Olja) J. Finn, University of Pittsburgh School of Medicine, AAI President; J. L. Miller, Senior Vice President, BioDiscovery, Invitrogen Corporation
Award Recipient: Richard A. Flavell, HHMI, Yale University School
of Medicine, Regulation of the immune response by cells and cytokines |
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Saturday, April 5: 6:00 PM – 7:30 PM
Young Experimental Scientists (Y.E.S.) Mixer Monday, April 7: 9:00 PM San Diego Marriott Hotel & Marina, Marina Ballroom G, Level 3 (South Tower)
The Y.E.S. Mixer is open to all EB registrants and is scheduled on
Monday, April 7, 9:00 PM-11:30 PM. You must wear your badge to gain
admittance. Dance, relax, network while enjoying complimentary snacks
and soft drinks. The EB sponsoring societies encourage responsible
drinking for those drinking alcohol. Alcohol will not be served to
anyone under the age of 21 (be prepared to show identification).
Young Experimental Scientists (Y.E.S.) Lounge San Diego Convention Center, Location TBD
Click here for more information: http://www.eb2008.org/YESMixer.htm
Refresher Course: Biology of the Lymph Node
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Four Perspectives Lymph nodes serve as crossroads of body fluid flow as well as checkpoints for alerting the body to invasions. Moreover, they serve as organizing centers for responses when such invasions occur. They also represent important examples of how organ distribution and structure provide a basis for understanding normal and pathological function. By combining speakers on basic lymph node structure and function together with those on issues regarding their importance in clinical medicine, we hope to promote an integrated understanding of the significance of these organs in immune function and health.
Speakers
AAI Business Meeting & Awards Presentation Tuesday, April 8: 12:45 PM; San Diego Convention Center, Room 31A This session will include the annual report to AAI members on AAI and The Journal of Immunology business affairs, and will feature the following 2008 AAI awards presentations. Lunch will be available (no ticket required).
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Symposium: Human Immunology as Informed by the Use of Targeted Therapeutics Sunday, April 6: 12:30 PM, San Diego Convention Center, Room 32 Chair: Joel D. Ernst, New York University School of Medicine Speakers Michael R. Ehrenstein, University College, London, Introduction; and Targeting regulatory T cells using anti-TNF in patients with rheumatoid arthritis Andrew C. Chan, Genentech, Inc., B cell immunotherapy: lessons from the clinic
Terry B. Strom,
Harvard
Medical School, Smart T cell targets
and the confounding role of inflammation
AAI Education Committee
John H. Wallace High School Teachers Workshop: Lessons in Immunology Sunday, April 6: 9:00 AM, San Diego Convention Center, Room 30E Chair: Brian A. Cobb, Case Western Reserve University School of Medicine The AAI High School Teachers Program brings the excitement of immunology directly to high school students by sending high school science teachers into the laboratories of established immunologists who mentor them in a “hands-on” summer internship. The teachers develop a science project for the classroom based on their summer experience. The teachers present their experiences and projects in this session.
2007-2008 AAI High School Teachers Program Participants
Teacher: Laurie E. Asermily, Seneca Falls Central School, Seneca Falls, NY Mentor: Jennifer Anolik, M.D., Ph.D., University of Rochester Medical Center, Rochester, NY
Teacher: Teresa R. Burke, Westford Academy, Westford, MA Mentor: William Walker Cruikshank, Ph.D., Boston University School of Medicine, Boston, MA
Teacher: Emily K. Faulconer, Lakeland High School, Suffolk City Public Schools, Suffolk, VA Mentor: Robert Eugene Ratzlaff, Ph.D., Old Dominion University, Norfolk, VA
Teacher: Dawn M. Martell, Wilmington High School, Wilmington, MA Mentor: William Walker Cruikshank, Ph.D., Boston University School of Medicine, Boston, MA
Teacher: Scott Troy, West High School, Denver Public Schools, Denver, CO Mentor: Raul M. Torres, Ph.D., University of Colorado Health Science Center, Denver, CO
Teacher: Elizabeth Withum, A.W. Coolidge Middle School, Reading, MA Mentor: Rachel M. McLoughlin, Ph.D., Brigham & Women’s Hospital, Harvard Medical School, Boston, MA Careers Roundtable (Co-sponsored with the Committee on the Status of Women) Sunday, April 6: 1:30 PM, San Diego Convention Center, Sails Pavilion Chair: Christine Milcarek, University of Pittsburgh School of Medicine, Chair, Committee on the Status of Women Experienced scientists will serve as roundtable discussion leaders on specific career issues and options important to men and women in science today. Attendance is limited to the first 300 registrants (students, postdocs, faculty, and staff). Men are encouraged to participate. Fee of $10 required when registering; coffee and dessert included..
GENERAL -- Topics related to the environment you work in or want to work in 1. Academic Research 2. Biotech and Industry 3. Governmental Agencies: CDC/FDA/NIH 4. Clinic: Clinical and diagnostic immunology, clinician-scientist 5. Undergraduate Institutions: teaching, doing research part-time
TRANSITIONS
-- Topics focused on a specific career
stage 7. Post-doc to PI: finding a position, interviewing, negotiating, lab start-up 8. New PI: attracting students and post-docs, preparing for tenure 9. Mid-Career: developing administrative and management skills/sabbaticals 10. Changing Careers: moving from academia to industry, or vice versa
SPECIAL -- Topics for unique situations 11. Career and Family: time management/family leave/professional couples 12. Integrity and Ethics: dealing with controversy, discrimination in the workplace 13. Alternative Careers: science journalism, patent Law 14. Politics of Science Research at Undergraduate Institutions: A
Balancing Act Skills for the Big Chill: How to Survive and Thrive as a Newly Independent Scientist Saturday, April 5: 2:45 PM, San Diego Convention Center, Room 30E Chair: Christopher A. Pennell, University of Minnesota-Twin Cities This workshop is for young investigators who want to be, or have recently become, Principal Investigators. The participants in this workshop will give tips on how to succeed at the next level in your career and will share valuable insights that no one else bothers to tell you. Speakers Christopher A. Pennell, University of Minnesota-Twin Cities, Succeeding as a PI: why you need more than science Brian A. Cobb, Case Western Reserve University School of Medicine, Making the transition: reflections on the first two independent years Andrea A. Itano, Amgen, Inc., From academics to biotech: what changes and what stays the same
Ross M. Kedl,
University of
Colorado Health Sciences Center,
From academics to biotech and back again: how to balance academics and
business
AAI Minority Affairs Committee
The 2008 Minority Affairs Committee Activities are funded by a grant from the National Institute of General Medical Sciences, National Institutes of Heath. [FASEB MARC Program: T36-GMO8059-25].
AAI Minority Scientist Travel Awards Program The Minority Affairs Committee supports the participation of under-represented minority scientists at the AAI Annual Meeting through committee activities and Minority Scientist Travel Awards. For complete information on all AAI Awards, please visit www.aai.org/Awards. The awards will be presented at the AAI Business Meeting.
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