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Saturday, April 5: 5:00 PM; San Diego Convention Center, Room 20 B/C/D
Olivera (Olja) J. Finn, University of Pittsburgh School of
Medicine, AAI President, Immunologic weapons acquired early in life
win battles with cancer late in life
Presentation of the AAI Lifetime Achievement Award Chair: Olivera (Olja) J. Finn, University of Pittsburgh School of Medicine, AAI President
Award recipient:
Robert R. Rich,
M.D., University of Alabama at Birmingham School of Medicine
Presidential Symposium
Taking Care of Immunology around the World Tuesday, April 8: 2:30 PM, San Diego Convention Center, Room 20 B/C/D
Chair: Olivera (Olja) J. Finn, University of Pittsburgh School
of Medicine, AAI President Xuetao Cao, Second Military Medical University Shanghai, President, Chinese Society of Immunology, Stromal microenvironment, regulatory dendritic cells, and regulation of immune response Cornelis J. M. Melief, Leiden University Medical Center, President, Dutch Society for Immunology, Immunotherapy of established lesions induced by high risk papilloma virus Ljiljana Sofronic-Milosavljevic, Institute for the Application of Nuclear Energy (INEP), Belgrade, Serbia, President, Immunological Society of Serbia, Taming of autoimmunity - Trichinella, worm under host-parasite contract Adrian C. Hayday, Guy's Hospital, General Secretary, British Society for Immunology, Immunosurveillance: molecular conversations between epithelial cells and the immune system Hermann J. Ziltener, The Biomedical Research Center, University of British Columbia, President, Canadian Society for Immunology, New roles for an old acquaintance: function of PSGL-1 in thymic homeostasis and a novel mechanism of naive T cell homing
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San Diego Convention Center, Room 20 B/C/D
Chair:
John G. Monroe, AAI Program
Chair, Genentech, Inc. Kathryn Calame, Columbia University
Blimp-1 and the Regulation of Lymphocyte Function
Monday, April 7: 5:00 PM San Diego Convention Center, Room 20 B/C/D Chair: John G. Monroe, AAI Program Chair, Genentech, Inc.
Marc K. Jenkins, University of Minnesota Medical School On the Trail of Epitope-Specific Naive Helper T Cells in Normal Individuals
Tuesday, April 8: 5:00 PM San Diego Convention Center, Room 20 B/C/D Chair: John G. Monroe, AAI Program Chair, Genentech, Inc.
Harinder Singh, HHMI University of Chicago
Gene Regulatory Networks Orchestrating Cell Fates in the Immune
System |
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Sunday, April 6, 2008 – 8:00 AM
Major Symposium A: Genetics of Autoimmunity
Chairs: Betty A. Diamond, Feinstein Institute for Medical Research;
Linda S. Wicker, Cambridge Institute for Medical Research Peter K. Gregersen, North Shore University Hospital, Rheumatoid arthritis in the genomic era: cracking the code for clues to autoimmune pathogenesis Gerald T. Nepom, Benaroya Research Institute, Probing for disease susceptibility Linda S. Wicker, Cambridge Institute for Medical Research, The IL-2/CD25 pathway determines susceptibility to type I diabetes in humans and NOD mice William M. Ridgway, University of Pittsburgh, Genetic control of autoimmune liver disease in NOD congenic mice Betty A. Diamond, Feinstein Institute for Medical Research, BCR signaling strength determines predisposition to autoantibody production
Major Symposium B: Microenvironmental Influence on Immune Function
Chairs:
Jason G. Cyster, University of California, San Francisco; Peter
J. Lane, University of Birmingham Jonathan W. Yewdell, NIAID, NIH, Getting real: intravital imaging of antiviral CD8+ T cell priming and effector function Shannon J. Turley, Dana Farber Cancer Institute, Harvard Medical School, Antigen presentation by lymph node stromal cells and dendritic cells Melody A. Swartz, Swiss Federal Institute of Technology, Lausanne, Mechanisms of dendritic cell homing towards and entry into lymphatic vessels Ellen A. Robey, University of California, Berkeley, Imaging host-pathogen interactions in a Toxoplasma gondii infection model
Jason G. Cyster, University of California, San Francisco,
Requirements for lymphocyte egress from lymphoid organs
Monday, April 7, 2008 – 8:00 AM
Major Symposium C: TNF Family Members in Inflammation, Autoimmunity,
and Cancer
Chairs: Michael Croft, La Jolla Institute for Allergy and
Immunology; Tania H. Watts, University of Toronto Michael Croft, La Jolla Institute for Allergy and Immunology, OX40 and the decision between tolerance and immunity Richard M. Siegel, NIAMS, NIH, TL1A/DR3 interactions in inflammation and autoimmunity Carlo Riccardi, University of Perugia, GITR/GITRL system in the regulation of the immune/inflammatory response
Carl F. Ware, La Jolla Institute for Allergy and Immunology,
The LIGHT and DARC sides of a TNF receptor
Major Symposium D: Organ-Specific Regulation of Innate Immunity
Chairs: Eyal Raz, University of California, San Diego; Robert
L. Modlin, University of California, Los Angeles Bali Pulendran, Emory University, Differences between gut and splenic macrophages Robert L. Modlin, University of California, Los Angeles, A TLR-induced vitamin D-dependent antimicrobial mechanism in microbial infection in skin and the lung Dean Sheppard, University of California, San Francisco, Organ-specific regulation of Th-17 and Treg induction through TGF-b activation by dendritic cells Andrea M. Cooper, Trudeau Institute, The protective vs. the pathogenic role of the innate cytokine IL-23 in the lung Jongdae Lee, University of California, San Diego, The uniqueness of TLR signaling in colonic epithelial cells
Bruce A. Beutler, The Scripps Research Institute,
Organ-specific innate immunity as dissected by ENU mutagenesis
Tuesday, April 8, 2008 – 8:00 AM
Major Symposium E: Managing B Cell Lifespan and Lifestyle with BAFF
Family Interactions
Chairs: Michael P. Cancro, University of Pennsylvania School of
Medicine; Fabienne Mackay, Garvan Institute of Medical Research Fabienne Mackay, Garvan Institute of Medical Research, The role of BAFF in autoimmunity is T cell-independent but requires MyD88 Signaling Andrea Cerutti, Weill Medical College of Cornell University, BAFF and APRIL: key innate regulators of immunoglobulin heavy chain class switching Jennifer Anolik, University of Rochester Medical Center, Determinants of B cell reconstitution after B cell depletion therapy in human autoimmune disease Jane A. Gross, Zymogenetics, Inc., B cell-targeting therapies for autoimmune diseases: are they all the same? Richard J. Bram, Mayo Clinic, TACI: Signaling and function in the immune system
Chairs: Yasmine Belkaid, NIAID, NIH; E. John Wherry, The
Wistar Institute Yasmine Belkaid, NIAID, NIH, Regulatory T cells during parasitic infections
JoAnne L. Flynn, University of Pittsburgh, Regulation of
immune responses in tuberculosis Markus Mohrs, Trudeau Institute, Tracking cytokine responses to infection
Christian Munz, Rockefeller University, Innate and adaptive
immunity through autophagy
Wednesday, April 9, 2008 – 8:00 AM
Major Symposium G: Control of Effector and Memory T Cell Fate
Chairs: Donna L. Farber, University of Maryland at Baltimore;
Steven L. Reiner, University of Pennsylvania Steven L. Reiner, Abramson Family Cancer Research Institute, University of Pennsylvania, Shaping the fate of T cells in response to infection Eric G. Pamer, Memorial Sloan-Kettering Cancer Center, Trafficking and differentiation of CD4 T cells during respiratory infections Richard M. Locksley, University of California, San Francisco, Initiating type-2 immunity Ananda W. Goldrath, University of California, San Diego, Making CD8 memory
Robert A. Seder, Vaccine Research Center, NIAID, NIH, The
quality of T cell responses determines protection
Major Symposium H: Can Basic Advances
in Immunology Generate Effective Cancer Therapies?
Chairs: Robert D. Schreiber, Washington University School of
Medicine; Carl H. June, University of Pennsylvania Glenn Dranoff, Dana Farber Cancer Institute, Harvard Medical School, The interplay of tumor immunity and inflammation Philip D. Greenberg, University of Washington, Generating and maintaining function of T cells with high avidity for tumor antigens Carl H. June, University of Pennsylvania, Adoptive transfer of lentiviral engineered T cells for cancer immunogene therapy James P. Allison, Memorial Sloan-Kettering Cancer Center, Immune responses to early vs. late stages of cancer
Cornelia Trimble, Johns Hopkins Medical Institutions,
Targeting adaptive immune responses for HPV disease |
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AAI Awards being presented at AAI's 95th Annual Meeting, in conjunction
with Experimental Biology 2008:
Details on awards presentations appear in the following two sections. |
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Supported through an unrestricted grant from the Dana Foundation Sunday, April 6: 3:15 PM; San Diego Convention Center, Room 20 B/C/D Chair: Olivera (Olja) J. Finn, University of Pittsburgh School of Medicine, AAI President
Award Recipient: James
P. Allison, HHMI, Memorial
Sloan-Kettering Cancer Center, Immune checkpoint blockade in cancer
therapy
AAI-BD Biosciences Investigator Award & Lecture Supported through an unrestricted educational grant from BD Biosciences Monday, April 7: 2:30 PM, San Diego Convention Center, Room 20 B/C/D Chairs: Olivera (Olja) J. Finn, University of Pittsburgh School of Medicine, AAI President; Robert Balderas, Vice President of Research and Development, BD Biosciences-Pharmingen, San Diego, CA
Award Recipient: Pamela L. Schwartzberg, National Human Genome
Research Institute, NIH, Integrating T cell signals: lessons from
mouse models and primary immune disorders
AAI-Invitrogen Meritorious Career Award and Lecture Supported by an unrestricted educational grant from Invitrogen Corporation Monday, April 7: 3:30 PM, San Diego Convention Center, Room 20 B/C/D Chair: Olivera (Olja) J. Finn, University of Pittsburgh School of Medicine, AAI President; J. L. Miller, Senior Vice President, BioDiscovery, Invitrogen Corporation
Award Recipient: Richard A. Flavell, HHMI, Yale University School
of Medicine, Regulation of the immune response by cells and cytokines |
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Saturday, April 5: 6:00 PM – 7:30 PM
Young Experimental Scientists (Y.E.S.) Mixer Monday, April 7: 9:00 PM San Diego Marriott Hotel & Marina, Marina Ballroom G, Level 3 (South Tower)
The Y.E.S. Mixer is open to all EB registrants and is scheduled on
Monday, April 7, 9:00 PM-11:30 PM. You must wear your badge to gain
admittance. Dance, relax, network while enjoying complimentary snacks
and soft drinks. The EB sponsoring societies encourage responsible
drinking for those drinking alcohol. Alcohol will not be served to
anyone under the age of 21 (be prepared to show identification).
Young Experimental Scientists (Y.E.S.) Lounge San Diego Convention Center, Location TBD
Click here for more information: http://www.eb2008.org/YESMixer.htm
Refresher Course: Biology of the Lymph Node
-
Four Perspectives Lymph nodes serve as crossroads of body fluid flow as well as checkpoints for alerting the body to invasions. Moreover, they serve as organizing centers for responses when such invasions occur. They also represent important examples of how organ distribution and structure provide a basis for understanding normal and pathological function. By combining speakers on basic lymph node structure and function together with those on issues regarding their importance in clinical medicine, we hope to promote an integrated understanding of the significance of these organs in immune function and health.
Speakers
AAI Business Meeting & Awards Presentation Tuesday, April 8: 12:45 PM; San Diego Convention Center, Room 31A This session will include the annual report to AAI members on AAI and The Journal of Immunology business affairs, and will feature the following 2008 AAI awards presentations. Lunch will be available (no ticket required).
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Symposium: Human Immunology as Informed by the Use of Targeted Therapeutics Sunday, April 6: 12:30 PM, San Diego Convention Center, Room 32 Chair: Joel D. Ernst, New York University School of Medicine Speakers Michael R. Ehrenstein, University College, London, Introduction; and Targeting regulatory T cells using anti-TNF in patients with rheumatoid arthritis Andrew C. Chan, Genentech, Inc., B cell immunotherapy: lessons from the clinic
Terry B. Strom,
Harvard
Medical School, Smart T cell targets
and the confounding role of inflammation
AAI Education Committee
John H. Wallace High School Teachers Workshop: Lessons in Immunology Sunday, April 6: 9:00 AM, San Diego Convention Center, Room 30E Chair: Brian A. Cobb, Case Western Reserve University School of Medicine The AAI High School Teachers Program brings the excitement of immunology directly to high school students by sending high school science teachers into the laboratories of established immunologists who mentor them in a “hands-on” summer internship. The teachers develop a science project for the classroom based on their summer experience. The teachers present their experiences and projects in this session.
2007-2008 AAI High School Teachers Program Participants
Teacher: Laurie E. Asermily, Seneca Falls Central School, Seneca Falls, NY Mentor: Jennifer Anolik, M.D., Ph.D., University of Rochester Medical Center, Rochester, NY
Teacher: Teresa R. Burke, Westford Academy, Westford, MA Mentor: William Walker Cruikshank, Ph.D., Boston University School of Medicine, Boston, MA
Teacher: Emily K. Faulconer, Lakeland High School, Suffolk City Public Schools, Suffolk, VA Mentor: Robert Eugene Ratzlaff, Ph.D., Old Dominion University, Norfolk, VA
Teacher: Dawn M. Martell, Wilmington High School, Wilmington, MA Mentor: William Walker Cruikshank, Ph.D., Boston University School of Medicine, Boston, MA
Teacher: Scott Troy, West High School, Denver Public Schools, Denver, CO Mentor: Raul M. Torres, Ph.D., University of Colorado Health Science Center, Denver, CO
Teacher: Elizabeth Withum, A.W. Coolidge Middle School, Reading, MA Mentor: Rachel M. McLoughlin, Ph.D., Brigham & Women’s Hospital, Harvard Medical School, Boston, MA Careers Roundtable (Co-sponsored with the Committee on the Status of Women) Sunday, April 6: 1:30 PM, San Diego Convention Center, Sails Pavilion Chair: Christine Milcarek, University of Pittsburgh School of Medicine, Chair, Committee on the Status of Women Experienced scientists will serve as roundtable discussion leaders on specific career issues and options important to men and women in science today. Attendance is limited to the first 300 registrants (students, postdocs, faculty, and staff). Men are encouraged to participate. Fee of $10 required when registering; coffee and dessert included..
GENERAL -- Topics related to the environment you work in or want to work in 1. Academic Research 2. Biotech and Industry 3. Governmental Agencies: CDC/FDA/NIH 4. Clinic: Clinical and diagnostic immunology, clinician-scientist 5. Undergraduate Institutions: teaching, doing research part-time
TRANSITIONS
-- Topics focused on a specific career
stage 7. Post-doc to PI: finding a position, interviewing, negotiating, lab start-up 8. New PI: attracting students and post-docs, preparing for tenure 9. Mid-Career: developing administrative and management skills/sabbaticals 10. Changing Careers: moving from academia to industry, or vice versa
SPECIAL -- Topics for unique situations 11. Career and Family: time management/family leave/professional couples 12. Integrity and Ethics: dealing with controversy, discrimination in the workplace 13. Alternative Careers: science journalism, patent Law 14. Politics of Science Research at Undergraduate Institutions: A
Balancing Act Skills for the Big Chill: How to Survive and Thrive as a Newly Independent Scientist Saturday, April 5: 2:45 PM, San Diego Convention Center, Room 30E Chair: Christopher A. Pennell, University of Minnesota-Twin Cities This workshop is for young investigators who want to be, or have recently become, Principal Investigators. The participants in this workshop will give tips on how to succeed at the next level in your career and will share valuable insights that no one else bothers to tell you. Speakers Christopher A. Pennell, University of Minnesota-Twin Cities, Succeeding as a PI: why you need more than science Brian A. Cobb, Case Western Reserve University School of Medicine, Making the transition: reflections on the first two independent years Andrea A. Itano, Amgen, Inc., From academics to biotech: what changes and what stays the same
Ross M. Kedl,
University of
Colorado Health Sciences Center,
From academics to biotech and back again: how to balance academics and
business
AAI Minority Affairs Committee
The 2008 Minority Affairs Committee Activities are funded by a grant from the National Institute of General Medical Sciences, National Institutes of Heath. [FASEB MARC Program: T36-GMO8059-25].
AAI Minority Scientist Travel Awards Program The Minority Affairs Committee supports the participation of under-represented minority scientists at the AAI Annual Meeting through committee activities and Minority Scientist Travel Awards. For complete information on all AAI Awards, please visit www.aai.org/Awards. The awards will be presented at the AAI Business Meeting.
AAI Committee on Public Affairs
Peer Review at
NIH: Making Sure the System Works (Joint EB Public Affairs Session)
Chair:
Olivera (Olja) J. Finn, University of Pittsburgh School of
Medicine, AAI President Speakers Lawrence A. Tabak, National Institute of Dental and Craniofacial Research, NIH; Co-Chair, Advisory Committee to the NIH Director Working Group on Peer Review Keith R. Yamamoto, University of California, San Francisco School of Medicine; Co-Chair, Advisory Committee to the NIH Director Working Group on Peer Review
AAI
Publications Committee Mini Course: Communication: The Science of Scientific Writing Saturday, April 5: 12PM-4:00 PM, San Diego Convention Center, Room 31A *registration required Instructor: Judith A. Swan, Assistant Director for Scientific and Technical Writing, Princeton Writing Program, Princeton University Improve the quality of your publications and grant applications! This half-day workshop will focus on the perspective of scientific writing that matters most -- that of the reader. Attendees will learn strategies for communicating clearly and gain new perspectives on excellent writing through examples and interactive class participation. Appropriate for scientists at all levels. Registration required as there is limited seating. $100 fee required when registering. The Publication Process: Advice and Admonitions Sunday, April 6: 12:30 PM, San Diego Convention Center Chair: Judy M. Teale, University of Texas at San Antonio Speakers Arthur Weiss, HHMI, University of California, San Francisco, Preparing a manuscript for publication: there really is an instruction manual Michael Rossner, The Rockefeller University Press, What’s in a picture? The temptation of data manipulation
Jeremy M. Boss,
Emory
University School of Medicine, To
accept, revise or reject – that is the question
AAI Committee on the Status of Women
Careers Roundtable (Co-sponsored with the AAI Education Committee) Sunday, April 6: 1:30 PM, San Diego Convention Center, Sails Pavilion Chair: Christine Milcarek, University of Pittsburgh School of Medicine, Chair, Committee on the Status of Women Experienced scientists will serve as roundtable discussion leaders on specific career issues and options important to men and women in science today. Attendance is limited to the first 300 registrants (students, postdocs, faculty, and staff). Men are encouraged to participate. Registration required as there is limited seating. $10 fee required when registering; coffee and dessert included.
GENERAL -- Topics related to the environment you work in or want to work in 1. Academic Research 2. Biotech and Industry 3. Governmental Agencies: CDC/FDA/NIH 4. Clinic: Clinical and diagnostic immunology, clinician-scientist 5. Undergraduate Institutions: teaching, doing research part-time
TRANSITIONS
-- Topics focused on a specific career
stage 7. Post-doc to PI: finding a position, interviewing, negotiating, lab start-up 8. New PI: attracting students and post-docs, preparing for tenure 9. Mid-Career: developing administrative and management skills/sabbaticals 10. Changing Careers: moving from academia to industry, or vice versa
SPECIAL -- Topics for unique situations 11. Career and Family: time management/family leave/professional couples 12. Integrity and Ethics: dealing with controversy, discrimination in the workplace 13. Alternative Careers: science journalism, patent Law 14. Politics of Science Workshop: Navigating Biomedical Research Careers Monday, April 7: 10:15 AM, San Diego Convention Center Chair: Jeremy M. Boss, Emory University School of Medicine Speakers Kathryn Calame, Columbia University College of Physicians and Surgeons, A very non-traditional career path Laurie A. Dempsey, Nature Publishing Group, Transiting from the bench to the editor’s chair—an odyssey
Andrew C. Chan,
Genentech,
Inc., Discovery AND translation—what
does it take?
AAI Veterinary Immunology Committee
AAI Veterinary Immunology Committee Co-sponsored with the American Association of Veterinary Immunologists (AAVI) Symposium: Comparative Biology of Dendritic Cells in Viral Infections Monday, April 7: 10:15 AM, San Diego Convention Center, Room 33 A/B Chairs: Christopher J. Davies, Washington State University; William T. Golde, Plum Island Animal Disease Center Speakers Simon M. Barratt-Boyes, University of Pittsburgh, Dendritic cell dynamics in simian immunodeficiency virus infection of monkeys Randy E. Sacco, National Animal Disease Center, Modulation of neonatal ruminant pulmonary dendritic cells in respiratory syncytial virus infection Thomas M. Moran, Mount Sinai School of Medicine, Kinetics of dendritic cell migration in mouse influenza virus infection
William T. Golde,
Plum
Island Animal Disease Center, Immune
function of multiple dendritic cell subsets during FMDV infection in
swine |
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National Cancer Institute (NCI) Symposium: Toll-Like Receptor Function in the Cancer Microenvironment Sunday, April 6: 8:00 AM, San Diego Convention Center, Room 33A/B Chairs: T. Kevin Howcroft, Division of Cancer Biology and Cancer Immunology, NCI, NIH; Rongfu Wang, Baylor College of Medicine Speakers T. Kevin Howcroft, Division of Cancer Biology and Cancer Immunology, NCI, NIH, Introduction Michael Karin, University of California, San Diego, IKK-dependent NF-kB signaling in inflammatory cancer Xiaoxia Li, Lerner Research Institute, Cleveland Clinic Foundation, The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis Rongfu Wang, Baylor College of Medicine, TLR signaling and regulatory T cells in cancer
Arthur M. Krieg,
Coley
Pharmaceutical Group, Clinical
development of TLR agonists for cancer therapy
National Institute of Allergy and Infectious Diseases (NIAID)
AAI-NIAID Contemporary Topics in Immunology Saturday, April 5: 12:00 PM, San Diego Convention Center, Room 32 Chairs: Alison Deckhut Augustine, NIAID, NIH; John G. Monroe, AAI Program Chair, Genentech, Inc. Speakers Vijay K. Kuchroo, Harvard Medical School, Reciprocal relationship between pathogenic Th17 and CD4+ CD25+ Treg cells Richard L. Gallo, University of California, San Diego, Mechanisms of immunomodulation by cathelicidin antimicrobial peptides Katherine A. Fitzgerald, University of Massachusetts Medical School, Signal integration in innate immunity K. Christopher Garcia, Stanford University School of Medicine, Structural insights into immune recognition NIAID Workshop: NIAID Funding Opportunities: Paylines and Special Programs Sunday, April 6: 12:30 PM, San Diego Convention Center, 33 A/B Chair: Helen Quill, Chief, Basic Immunology, DAIT, NIAID, NIH
Presenters Lynda Chiodetti, DAIT, NIAID, NIH NIAID Workshop: B Cells, Antibodies, and HIV Vaccines Sunday, April 6: 10:15 AM, San Diego Convention Center, Room 33 A/B Chairs: Helen Quill, DAIT, NIAID, NIH; Anthony Conley, DAIDS, NIAID, NIH Panelists Susan W. Barnett, Novartis Vaccines and Diagnostics, Inc. Gail A. Bishop, University of Iowa Dennis R. Burton, The Scripps Research Institute Shane Crotty, La Jolla Institute of Allergy and Immunology David Nemazee, The Scripps Research Institute Douglas D. Richman, University of California San Diego The purpose of this workshop is to challenge basic immunologists with a fascinating immunological quandary: why don't we generate broadly neutralizing antibodies to HIV-1? What is wrong with the immune system anyway? Audience participation is strongly encouraged and the discussion will be led by a dynamic panel of basic B cell immunologists together with HIV experts to dissect the immunological roadblocks preventing effective induction of broadly neutralizing antibodies by candidate HIV vaccines. The goal is to break with conventional thinking and elicit novel ideas and approaches that harness recent immunological advances to attack this devastating disease. Here is a chance to put your work to work!
National Institute on Aging (NIA)
National Institute on Aging (NIA) Symposium: How Aging Impacts Immunity Tuesday, April 8: 8:00 AM, San Diego Convention Center, Room 31A Chairs: Rebecca A. Fuldner, NIA, NIH; Phyllis-Jean Linton, Sidney Kimmel Cancer Center Speakers Kenneth A. Dorshkind, UCLA School of Medicine, Cell and molecular causes of B lineage aging Gregory D. Sempowski, Duke Human Vaccine Institute, Modulation of thymopoiesis across the lifespan Phyllis-Jean Linton, Sidney Kimmel Cancer Center, Alterations in dendritic cells of the aged
David L. Woodland,
Trudeau
Institute, Immunologic memory to
respiratory virus infections: the detrimental and beneficial effects of
aging |
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AAI is joined by the following guest societies presenting symposia in special disciplines.
American Association of Veterinary Immunologists (AAVI) Co-sponsored with the AAI Veterinary Immunology Committee Symposium: Comparative Biology of Dendritic Cells in Viral Infections Monday, April 7: 10:15 AM, San Diego Convention Center, Room 33 A/B Chairs: Christopher J. Davies, Washington State University; William T. Golde, Plum Island Animal Disease Center Speakers Simon M. Barratt-Boyes, University of Pittsburgh, Dendritic cell dynamics in simian immunodeficiency virus infection of monkeys Randy E. Sacco, National Animal Disease Center, Modulation of neonatal ruminant pulmonary dendritic cells in respiratory syncytial virus infection Thomas M. Moran, Mount Sinai School of Medicine, Kinetics of dendritic cell migration in mouse influenza virus infection William T. Golde, Plum Island Animal Disease Center, Immune function of multiple dendritic cell subsets during FMDV infection in swine
Association of Medical Laboratory Immunologists (AMLI): Prognostic and Diagnostic Markers of Inflammatory Diseases Sunday, April 6: 2:45 PM, San Diego Convention Center, Room 31A Chairs: Ronald J. Harbeck, National Jewish Medical and Research Center; Kenneth D. Beaman, Rosalind Franklin University of Medicine and Science Speakers Anne I. Sperling, University of Chicago, Up-shifting and down-shifting the Th2-mediated inflammatory response Kenneth D. Beaman, Rosalind Franklin University of Medicine and Science, Intracellular cytokine expression as a diagnostic tool for inflammatory diseases Evangelos Ntrivalas, Rosalind Franklin University of Medicine and Science, IL-6 gene polymorphisms as a predicator of the immune response Ronald J. Harbeck, National Jewish Medical and Research Center, Biomarkers in inflammatory lung diseases
American Society of Transplantation (AST): Why Don’t We Accept a Transplanted Organ? San Diego Convention Center Saturday, April 5: 2:45PM; San Diego Convention Center, Room 33 A/B Chairs: Robert L. Fairchild, Cleveland Clinic Foundation; Sheri M. Krams, Stanford University School of Medicine Adrian E. Morelli, University of Pittsburgh School of Medicine, Role of dendritic cells in the initiation of allograft rejection Kenneth A. Newell, Emory University, Activation of donor-reactive T cells in allograft rejection Ronald G. Gill, University of Alberta/Alberta Diabetes Institute, T cell effector functions in acute rejection Elaine F. Reed, Antibody-mediated rejection of allografts Roslyn B. Mannon, NIDDK, NIH, Immune mediated development of late transplant graft failure Roslyn B. Mannon, NIDDK, NIH, How the transplant physician views basic science findings for patient care
Canadian Society for Immunology (CSI): The Role of Cytoskeleton and Membrane Dynamics in Immune Cell Activation Sunday, April 6: 10:15 AM, San Diego Convention Center, Room 32 Chair: Michael R. Gold, University of British Columbia, Vancouver Speakers Sergio Grinstein, Hosp. for Sick Children, Toronto, Membrane remodeling alters surface charge and dictates the distribution of signaling molecules during phagocytosis Katherine A. Siminovitch, Samuel Lunenfeld Research Institute, Toronto, Roles of actin regulatory proteins in immune cell migration Hanne L. Ostergaard, University of Alberta, Edmonton, Signals leading to cytotoxic T cell-mediated killing Michael R. Gold, University of British Columbia, Vancouver, The Rap1 GTPase regulates B cell morphology, immune synapse formation, and signaling by particulate BCR ligands
Chinese Society for Immunology (ChSI): Immunological Research in China Monday, April 7: 10:15 AM, San Diego Convention Center, Room 31 B/C Chairs: Xuetao Cao, President, Chinese Society for Immunology, Second Military Medical University Shanghai; Olivera (Olja) J. Finn, President, The American Association of Immunologists, University of Pittsburgh School of Medicine Speakers Xuetao Cao, Institute of Immunology, Second Military Medical University Shanghai, Immunological research in China: the past, current and future Zhigang Tian, Institute of Immunology, University of Science and Technology of China, Hefei, Regulatory innate lymphocytes in autoimmune liver injury Wei He, Department of Immunology, Chinese Academy of Medical Sciences, Beijing, Human gamma/delta T cells: molecular basis in CDR3 for antigenic recognition, new ligands for TCR gamma/delta and regulatory function in immune responses Bing Sun, Inst. Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, Trichosanthin is a novel Th2-type adjuvant for inducing airway inflammation Liwei Lu, Department of Pathology, The University of Hong Kong, B cell maturation and its dysregulation in autoimmunity
International Society of Developmental and Comparative Immunology (ISDCI): Symposium of Comparative Immunology, Celebrating the Careers of Jack Marchalonis and Rene Stet Tuesday, April 8: 12:30 PM, San Diego Convention Center, Room 31 B/C Chair: Kenneth Söderhäll, President, ISDCI , Uppsala University Speakers Kenneth Söderhäll, Uppsala University, The pro-PO system in innate immunity in the invertebrates Christopher J. Secombes, University of Aberdeen, How conserved are Th cytokine loci in vertebrates? Valerie S. Hohman, University of San Diego, Evolution of the J chain
John E. Butler,
University of Iowa Medical School,
Antibody repertoire
development in fetal and neonatal piglets
International Society of Neuroimmunology (ISNI): Regulatory Influences on CNS Autoimmune Disease Sunday, April 6: 2:45 PM, San Diego Convention Center, Room 31 B/C Chairs: Caroline C. Whitacre, Ohio State University; Benjamin M. Segal, University of Michigan Speakers: Benjamin M. Segal, University of Michigan, The role of the innate immune system in active regulation of CNS autoimmunity Amy E. Lovett-Racke, Ohio State University, Silencing T-bet suppresses Th1 and Th17 cell differentiation Amit Bar-Or, Montreal Neurological Institute of McGill University, B cells in multiple sclerosis
Caroline C. Whitacre,
Ohio
State University, Pregnancy: a
profound regulator of CNS autoimmune disease
PsychoNeuroImmunology Research Society (PNIRS): Neurotransmitters, Inflammation and Disease Sunday, April 6: 12:30 PM, San Diego Convention Center, Room 31 B/C Chair: Keith W. Kelley, University of Illinois College of Medicine Speakers Keith W. Kelley, University of Illinois College of Medicine, Overview: Neurotransmitters, inflammation and disease Serge Rivest, Laval University, Role of the innate immune system in brain diseases and repair Kevin J. Tracey, Feinstein Institute for Medical Research, Physiology and anatomy of the cholinergic anti-inflammatory pathway Steve W. Cole, UCLA School of Medicine, Stress and lymph mode innervation: impact on HIV/SIV replication Doina Ganea, Temple University School of Medicine, Immunosuppressive neuropeptides: role in peripheral and CNS inflammation
Society for Leukocyte Biology (SLB): Dendritic Cells and Immunoregulation in Infectious Diseases Monday, April 7: 2:45 PM, San Diego Convention Center, Room 32 Chair: Christopher L. Karp, Cincinnati Children’s Hospital Medical Center Speakers Julio C. Aliberti, Cincinnati Children’s Hospital Medical Center, Lipoxin-mediated control of innate immunity to infection Akiko Iwasaki, Yale University School of Medicine, Autophagy and antiviral immunity Joel D. Ernst, New York University School of Medicine, Dendritic cells as targets and hosts for M. tuberculosis in vivo David L. Sacks, NIAID, NIH, Influence of infected and apoptotic neutrophils on the immune response to leishmania
Sociedad Mexicana de Inmunología (SMI): Immunology in Mexico Monday, April 7: 10:15 AM, San Diego Convention Center, Room 32 Chairs: Constantino Lopez-Macias, Medical Research Unit on Immunochemistry; Centro Médico Nacional; Clara Gorodezky, Department of Immunology and Immunogenetics, InDRE, SSA Speakers José Moreno-Rodriguez, UIM en Enfermedades Autoinmunes, SOCS1 expression in systemic lupus erythematosus Constantino Lopez-Macias, Medical Research Unit on Immunochemistry, A novel adjuvant composed of Papaya Mosaic Virus promotes protection by translating innate response into long-lasting antibody responses Clara Gorodezky, Department of Immunology and Immunogenetics, InDRE, SSA, Epidemiological impact of MHC polymorphism: Mexican natives as an example
The Society for Mucosal Immunology (SMI): Immune Regulation and Mucosal Homeostasis Monday, April 7: 2:45 PM, San Diego Convention Center, Room 31 B/C Chairs: Charlotte S. Kaetzel, University of Kentucky; Leo Lefrançois, University of Connecticut Health Center Speakers Peter B. Ernst, University of Virginia, Adenosine: a new player in regulatory T cell biology Lynn Puddington, University of Connecticut Health Center, Maternal instructions during development of immune responsiveness
Atsushi Kitani,
NIAID, NIH, NOD-like receptors and
regulation of intestinal inflammation
The Society for Natural Immunity (SNI): Regulation of NK Cells and Innate Immunity—A Symposium in Memory of Paul Leibson Sunday, April 6: 8:00 AM, San Diego Convention Center, Room 32 Chairs: Eric O. Long, NIAID, NIH; Lewis L. Lanier, University of California, San Francisco Speakers Eric O. Long, NIAID, NIH, Signaling by inhibitory receptors Vinay Kumar, University of Chicago, Regulation of CD244 functions Ulrich von Andrian, Harvard Medical School, Innate immune responses in skin-draining lymph nodes and beyond
Lewis L. Lanier,
University of California, San Francisco, NK receptors and signaling |
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Submitted abstracts are programmed into oral or poster sessions; oral sessions are called Block Symposia. Each abstract selected for a Block Symposium will also be presented in a Poster Session. The following AAI Block Symposia will be presented at Experimental Biology 2008; all sessions will be held in the San Diego Convention Center. For a detailed Block Symposia schedule, click here.
Saturday, April 5
12:00 PM - 2:00 PM Cytokines in Autoimmunity and Hypersensitivity (Room 33 A/B) Host Immune Responses to Influenza Virus (Room 31 B/C) Thymopoiesis and T Cell Homeostasis (Room 30E)
2:45 PM - 4:45 PM Immune Modulation During Persistent Infections (Room 31 B/C)
Sunday, April 6
8:00 AM – 9:45 AM Early Cell Lineage Restrictions in Hematopoiesis (Room 31A)
8:00 AM– 10:00 AM T Cell Responses to Infection: From Recognition to Memory Formation (Room 31 B/C)
10:15 AM - 12:15 PM CD4 and CD8 Memory (Room 31 B/C) Immunological Impact of Antigen Processing and Presentation (Room 31A)
12:30 PM - 2:30 PM Tumor-Associated Immunosuppression, Mechanisms of Tumor Rejection and Modulation of the Immune Response (Room 31A)
2:45 PM - 4:45 PM T Cell Development (Room 33 A/B)
Monday, April 7
8:00 AM – 10:00 AM Genetic and Epigenetic Regulation of the Immune System I (Room 33 A/B) Immunotherapy of Cancer, Vaccine Development and Immune-Based Therapies (Room 31A) Mucosal Surfaces: Inflammation Control Centers (Room 32) Regulation of B Cell Responses (Room 30E) Regulation of Inflammatory Responses (Room 31 B/C)
12:30 PM - 2:30 PM IL-17 Family of Cytokines (Room 33 A/B) Mast Cell and Basophil Activation and Survival (Room 31 B/C) New Therapeutic Strategies For Autoimmune Diseases (Room 30E) T Cell Signaling (Room 32)
2:45 PM - 4:45 PM Anti-Tumor Effector Cells and Regulation of Tumor Immunity (Room 30E) Treg and Th17 Cells as Modulators of Autoimmunity (Room 33 A/B)
Tuesday, April 8
8:00 AM – 10:00 AM Leukocyte/Endothelial Cell Adhesion Mechanisms (Room 30E) Pathogenesis of Autoimmunity I: The Genetic Predisposition to Autoimmunity (Room 32) Regulation of Effector Function and Homeostasis by Cytokines (Room 33 A/B) Targets and Therapeutics in Allergic Disease (Room 31 B/C)
10:15 AM – 12:15 PM Immune Tolerance and Homeostasis (Room 33 A/B) Innate Immunity (Room 31 B/C) Leukocyte Migration in Innate and Adaptive Immunity (Room 31A) Pathogenesis of Autoimmunity II: Triggers of Autoimmunity (Room 32) Transplantation Immunology (Room 30E)
12:30 PM – 2:30 PM B Cell Development (Room 32) Friend or Foe? Mechanisms for Sampling Mucosal Microenvironments (Room 30E) Lymphocyte Activation, Signaling and Survival (Room 33 A/B)
2:45 PM – 4:45 PM Genetic and Epigenetic Regulation of the Immune System II (Room 33 A/B) Host Defense Against Parasitic and Fungal Pathogens (Room 30E) Regulatory T Cells (Room 32) Tumor-Associated Antigens and Pathobiology of the Immune System (Room 31 B/C)
Wednesday, April 9
8:00 AM – 8:45 AM Comparative Structure/Function of Antibody Molecules (Room 33 A/B)
9:00 AM – 10:00 AM Comparative Immunobiology of Host Cellular Responses (Room 33 A/B)
8:00 AM – 10:00 AM Development of Host Defense to Bacterial Infection (Room 30E) Mechanisms of T Cell Activation and Inactivation (Room 31A) Peripheral B Lineage Development and B Cell Immunity (Room 31 B/C) TLRs and Signaling Pathways (Room 32 A/B)
10:15 AM - 12:15 PM Cell Biology and Molecular Mechanisms of Antigen Processing and Presentation (Room 30E) Cellular Mechanisms of Hypersensitivity (Room 31 B/C) Dendritic Cell and Monocyte Regulation (Room 32) Enhancing Mucosal Immunity (Room 31A)
Vaccines and Immunotherapeutics Against Microbial
Infections (Room 33 A/B) |
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The most interactive part of the meeting! Discuss data and research issues firsthand with authors at the Poster Sessions. Posters will be displayed Sunday through Tuesday in the San Diego Convention Center, Exhibit Hall, from 7:30 AM – 6:00 PM, with authors present from 12:30-1:30 PM. AAI Poster sessions to be presented at Experimental Biology 2008 include: Sunday, April 6 AAI Education Committee-John H.
Wallace High School Teachers Workshop: Lessons in Immunology Monday, April 7 Antigen-Specific T Cell Responses to
Infection Tuesday, April 8 Anti Tumor Effector Cells and
Regulation of Tumor Immunity Wednesday, April 9
Late-Breaking Poster Sessions (TBA) |
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Submit an
Abstract --
AAI Annual Meeting (EB 2008)
Late-Breaking Abstract Submission Site
NOW OPEN |
The American Association of
Immunologists (AAI)
9650 Rockville Pike * Bethesda, MD 20814
301-634-7178 *
infoaai@aai.org
www.aai.org